scholarly journals Lower Insulin Secretion Is Associated with Hippocampal and Parahippocampal Gyrus Atrophy in Elderly Patients with Type 2 Diabetes Mellitus

2021 ◽  
Author(s):  
Yuko Adachi ◽  
Kazuki Ota ◽  
Isao Minami ◽  
Tetsuya Yamada ◽  
Takayuki Watanabe
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Insulin Secretion ◽  
Elderly Patients ◽  
Parahippocampal Gyrus

572-P: Lower Insulin Secretion Is Associated with Parahippocampal Gyrus Atrophy in Elderly Patients with Type 2 Diabetes Mellitus

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 572-P
Author(s):  
YUKO ADACHI ◽  
KAZUKI OTA ◽  
RYOKO ISHII ◽  
KEIHO CHO ◽  
YUKI HIRAMATSU ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Insulin Secretion ◽  
Elderly Patients ◽  
Parahippocampal Gyrus

Abstract #295 GLP-1 Receptor Agonists and Death From Any Cause in Elderly Patients with Type 2 Diabetes Mellitus: A Post-Hoc Analysis

2018 ◽  
Vol 24 ◽  
pp. 80-81
Author(s):  
Konstantinos Toulis ◽  
Krishna Gokhale ◽  
G. Neil Thomas ◽  
Wasim Hanif ◽  
Krishnarajah Nirantharakumar ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Elderly Patients ◽  
Post Hoc Analysis ◽  
Receptor Agonists ◽  
Post Hoc

Echinops Spp. Polysaccharide B Ameliorates Metabolic Abnormalities in a Rat Model of Type 2 Diabetes Mellitus

2020 ◽  
Vol 19 (1) ◽  
pp. 106-114
Author(s):  
Guang Hao ◽  
Xiaoyu Ma ◽  
Mengru Jiang ◽  
Zhenzhen Gao ◽  
Ying Yang
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Insulin Secretion ◽  
Insulin Receptor ◽  
Skeletal Muscles ◽  
Insulin Receptor Substrate ◽  
Sprague Dawley

This study examined the in vivo effects of Echinops spp. polysaccharide B on type 2 diabetes mellitus in Sprague-Dawley rats. We constructed a type 2 diabetes mellitus Sprague-Dawley rat models by feeding a high-fat and high-sugar diet plus intraperitoneal injection of a small dose of streptozotocin. Using this diabetic rat model, different doses of Echinops polysaccharide B were administered orally for seven weeks. Groups receiving Xiaoke pill and metformin served as positive controls. The results showed that Echinops polysaccharide B treatment normalized the weight and blood sugar levels in the type 2 diabetes mellitus rats, increased muscle and liver glycogen content, improved glucose tolerance, increased insulin secretion, and reduced glucagon and insulin resistance indices. More importantly, Echinops polysaccharide B treatment upregulated the expression of insulin receptor in the liver, skeletal muscles, and pancreas, and significantly improved the expression levels of insulin receptor substrate-2 protein in the liver and pancreas, as well as it increased insulin receptor substrate-1 expression in skeletal muscles. These two proteins play crucial roles in increasing insulin secretion and in controlling type 2 diabetes mellitus. The findings of the present study suggest that Echinops polysaccharide B could improve the status of diabetes in type 2 diabetes mellitus rats, which may be achieved by improving insulin resistance. Our study provides a new insight into the development of a natural drug for the control of type 2 diabetes mellitus.

Kcne2 deletion impairs insulin secretion and causes type 2 diabetes mellitus

2017 ◽  
Vol 31 (6) ◽  
pp. 2674-2685 ◽  
Author(s):  
Soo Min Lee ◽  
Jasmine Baik ◽  
Dara Nguyen ◽  
Victoria Nguyen ◽  
Shiwei Liu ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Insulin Secretion

scholarly journals The effect of pharmaceutical care in the elderly patients with type 2 diabetes mellitus

2016 ◽  
Vol 11 (1) ◽  
pp. 93-94 ◽  
Author(s):  
Win Myat Maw ◽  
Mi Mi Saw ◽  
Theingi Kyaw ◽  
Khin Ohnmar Kyaing ◽  
Zaw Min Latt ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Elderly Patients ◽  
Pharmaceutical Care ◽  
The Elderly

scholarly journals Link between vitamin B12, type 2 diabetes mellitus, and bone mineral density in elderly patients

2015 ◽  
Vol 6 (4) ◽  
pp. 120-124 ◽  
Author(s):  
Moatassem S. Amer ◽  
Randa Ali-Labib ◽  
Tamer M. Farid ◽  
Doha Rasheedy ◽  
Mohammad F. Tolba
Keyword(s):  
Diabetes Mellitus ◽  
Bone Mineral Density ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Elderly Patients ◽  
Vitamin B12 ◽  
Bone Mineral ◽  
Mineral Density
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