scholarly journals Investigating the role of dachshund b in the development of the pancreatic islet in zebrafish

2021 ◽  
Author(s):  
Lingling Yang ◽  
Sarah E. Webb ◽  
Nana Jin ◽  
Heung Man Lee ◽  
Ting Fung Chan ◽  
...  
Keyword(s):  
Pancreatic Islet

The Role of Islet Neogeneis-Associated Protein (INGAP) in Pancreatic Islet Neogenesis

2009 ◽  
Vol 10 (1) ◽  
pp. 37-45 ◽  
Author(s):  
Gary Pittenger ◽  
David Taylor-Fishwick ◽  
Aaron Vinik
Keyword(s):  
Pancreatic Islet ◽  
Islet Neogenesis

Increased islet blood flow in obese rats: role of the autonomic nervous system

1992 ◽  
Vol 262 (5) ◽  
pp. E736-E740 ◽  
Author(s):  
N. Atef ◽  
A. Ktorza ◽  
L. Picon ◽  
L. Penicaud
Keyword(s):  
Blood Flow ◽  
Insulin Secretion ◽  
Pancreatic Islet ◽  
Ventromedial Hypothalamus ◽  
Zucker Rats ◽  
Islet Blood Flow ◽  
Obese Rats ◽  
Increased Sensitivity ◽  
Obese Zucker Rats

Hyperinsulinemia, a main feature of both human and animal obesity, has been demonstrated to be due to both an increased sensitivity to nutrient secretagogues and an impairment of the nervous regulation of insulin secretion. Recent studies have shown that pancreatic islet blood flow increases under conditions associated with an enhanced insulin secretion. The aim of this study was to determine whether or not changes in islet blood flow are present in hyperinsulinemic obese rats. Using the nonradioactive microsphere technique, we were able to show a significantly higher islet blood flow in obese rats either of the Zucker strain or Wistar rats after lesion of the ventromedial hypothalamus than in their respective lean controls. Subdiaphragmatic vagotomy had no significant effect on basal islet blood flow of lean rats, whereas it decreased significantly that of obese Zucker rats. Conversely, clonidine, an alpha 2-adrenergic agonist, induced a higher decrease of islet blood flow in obese than in lean Zucker rats. The injection of an intravenous bolus of glucose (375 mg/kg iv) increased significantly more islet blood flow in obese than in lean Zucker rats. It is concluded that obese rats present an increased pancreatic islet blood flow, which may result, at least in part, from exaggerated parasympathetic activity and lower than normal sympathetic activity. This could participate in the hyperinsulinemia observed in these rats.

Expression and role of ionotropic glutamate receptors in pancreatic islet cells

1995 ◽  
Vol 9 (8) ◽  
pp. 686-691 ◽  
Author(s):  
Nobuya Inagaki ◽  
Hiroshi Kuromi ◽  
Tohru Gonoi ◽  
Yoshimasa Okamoto ◽  
Hitoshi Ishida ◽  
...  
Keyword(s):  
Glutamate Receptors ◽  
Pancreatic Islet ◽  
Islet Cells ◽  
Ionotropic Glutamate Receptors ◽  
Pancreatic Islet Cells

Technique, Complications, and Therapeutic Efficacy of Percutaneous Transplantation of Human Pancreatic Islet Cells in Type 1 Diabetes: The Role of US

Radiology ◽  
2005 ◽  
Vol 234 (2) ◽  
pp. 617-624 ◽  
Author(s):  
Massimo Venturini ◽  
Enzo Angeli ◽  
Paola Maffi ◽  
Paolo Fiorina ◽  
Federico Bertuzzi ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Pancreatic Islet ◽  
Therapeutic Efficacy ◽  
Islet Cells ◽  
Pancreatic Islet Cells ◽  
Human Pancreatic Islet

scholarly journals Role of caspases in the regulation of apoptotic pancreatic islet beta-cells death

2004 ◽  
Vol 200 (2) ◽  
pp. 177-200 ◽  
Author(s):  
Hongxiang Hui ◽  
Francesco Dotta ◽  
Umberto Di Mario ◽  
Riccardo Perfetti
Keyword(s):  
Beta Cells ◽  
Pancreatic Islet ◽  
Islet Beta Cells ◽  
Pancreatic Islet Beta Cells ◽  
Cells Death
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