scholarly journals Does the breakdown of the detoxification system for aldehydes as a result of aldose reductase upregulation lead to alcohol‐induced liver injury in humans and mice?

2020 ◽  
Vol 11 (6) ◽  
pp. 1426-1430
Author(s):  
Nigishi Hotta ◽  
Takahiko Kawamura ◽  
Toshitaka Umemura
Keyword(s):  
Liver Injury ◽  
Aldose Reductase ◽  
Detoxification System

988 - Aldose Reductase Null Mice are Protected Against Alcohol-Induced Hepatic ER Stress, Apoptosis and Liver Injury

2018 ◽  
Vol 154 (6) ◽  
pp. S-1111-S-1112
Author(s):  
Min Wang ◽  
Wei-Yang Chen ◽  
Leila Gobejishvili ◽  
Shirish Barve ◽  
Craig J. McClain ◽  
...  
Keyword(s):  
Liver Injury ◽  
Er Stress ◽  
Aldose Reductase

scholarly journals Aldose reductase functions as a detoxification system for lipid peroxidation products in vasculitis

1999 ◽  
Vol 103 (7) ◽  
pp. 1007-1013 ◽  
Author(s):  
Heike L. Rittner ◽  
Verena Hafner ◽  
Piotr A. Klimiuk ◽  
Luke I. Szweda ◽  
Jörg J. Goronzy ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Aldose Reductase ◽  
Lipid Peroxidation Products ◽  
Detoxification System

Effects of Steroids on Fetal Rat Liver

1969 ◽  
Vol 27 ◽  
pp. 350-351
Author(s):  
F. G. Zaki
Keyword(s):  
Liver Injury ◽  
Rat Liver ◽  
Fetal Liver ◽  
Dosage Level ◽  
Maternal Plasma ◽  
Methyl Prednisolone ◽  
Fetal Rat ◽  
Toxic Agents ◽  
Fetal Rat Liver ◽  
Neonatal Liver

Fetal and neonatal liver injury induced by agents circulating in maternal plasma, even though well recognized, its morphological manifestations are not yet established. As part of our studies of fetal and neonatal liver injury induced by maternal nutritional disorders, metabolic impairment and toxic agents, the effects of two anti-inflammatory steroids have been recently inves tigated.Triamcinolone and methyl prednisolone were injected each in a group of rats during pregnancy at a-dosage level of 2 mgm three times a week. Fetal liver was studied at 18 days of gestation. Litter size and weight markedly decreased than those of control rats. Stillbirths and resorption were of higher incidence in the triamcinolone group than in those given the prednisolone.

Proteinase activated receptor (PAR)-2 agonistic peptide protects from Th-1 mediated liver injury in mice

2001 ◽  
Vol 120 (5) ◽  
pp. A27-A27
Author(s):  
S FLORUCCI ◽  
A MENCARELLI ◽  
B PALAZZETTI ◽  
E DISTRUTTI ◽  
G CIRINO ◽  
...  
Keyword(s):  
Liver Injury ◽  
Th 1

Toll-like receptor 2 signaling is important for fas ligand on NKT cells, may contribute to liver injury induced by Salmonella infection

2001 ◽  
Vol 120 (5) ◽  
pp. A357-A357
Author(s):  
H SHIMIZU ◽  
Y FUKUDA ◽  
I NAKANO ◽  
Y KATANO ◽  
K NAGANO ◽  
...  
Keyword(s):  
Liver Injury ◽  
Fas Ligand ◽  
Nkt Cells ◽  
Toll Like Receptor ◽  
Salmonella Infection ◽  
Toll Like Receptor 2

Oral contraceptives worsen endotoxin induced liver injury in rats

2001 ◽  
Vol 120 (5) ◽  
pp. A116-A116
Author(s):  
A KONNO ◽  
N ENOMOTO ◽  
M HIROSE ◽  
K IKEJIMA ◽  
S MATSUYAMA ◽  
...  
Keyword(s):  
Liver Injury ◽  
Oral Contraceptives

Alterations of Glucose Metabolism in Viral and Toxic Liver Injury

1964 ◽  
Vol 46 (4) ◽  
pp. 424-433 ◽  
Author(s):  
Kurt J. Isselbacher ◽  
Wallace A. Jones
Keyword(s):  
Glucose Metabolism ◽  
Liver Injury ◽  
Toxic Liver Injury
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