scholarly journals Effect of renal impairment on cognitive function during a 3-year follow up in elderly patients with type 2 diabetes: Association with microinflammation

2014 ◽  
Vol 5 (5) ◽  
pp. 597-605 ◽  
Author(s):  
Takahiko Kawamura ◽  
Toshitaka Umemura ◽  
Hiroyuki Umegaki ◽  
Rui Imamine ◽  
Naoko Kawano ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Cognitive Function ◽  
Renal Impairment ◽  
Elderly Patients

scholarly journals Effectiveness of Solution-based Therapy on Self-Compassion and Reducing Blood Glucose in Elderly Patients with Type 2 Diabetes

2020 ◽  
pp. 158-164
Keyword(s):  
Type 2 Diabetes ◽  
Blood Glucose ◽  
Elderly Patients ◽  
Control Group ◽  
Old Patients ◽  
Statistical Population ◽  
Self Compassion ◽  
Effect Of Treatment

Introduction and Objectives: One of the problems of diabetes in the elderly is the likelihood of another condition that makes it more difficult to control blood sugar. This study aimed to investigate the effectiveness of solution-based therapy on self-compassion and blood glucose reduction in elderly patients with type 2 diabetes. Materials and Methods: This quasi-experimental study was conducted based on a pretest-posttest design with a control group and follow-up. The statistical population of the study consisted of 60-75-year-old patients with type 2 diabetes referring to Iranian Diabetes Association treatment centers in Tehran, Iran. A total of 36 patients were selected and randomly assigned into two groups of experimental and control. The data were collected using a self-compassion questionnaire and glycated hemoglobin test (HbA1c). The HbA1c test was also administered two months after the end of the training to follow-up and evaluate the sustainability of the treatment effects. The data were analyzed in SPSS software (version 26) through repeated measure ANOVA. Results: The results showed that the solution-based therapy increased self-compassion in the posttest phase (P<0.01), and the effect of treatment was maintained after two months (P<0.01). Moreover, solution-based therapy reduced blood glucose levels in the posttest phase (P<0.01) and retained the effect of treatment after two months (P<0.01). Conclusion: It can be concluded that solution-based therapy has effects on self-compassion and hyperglycemia in elderly patients with type 2 diabetes; moreover, it can be used in treatment centers to improve the status of patients with diabetes.

scholarly journals Impact of Obstructive Sleep Apnea Complicated With Type 2 Diabetes on Long‐term Cardiovascular Risks and All-cause Mortality in Elderly Patients

2021 ◽  
Author(s):  
Xiaofeng Su ◽  
JianHua Li ◽  
Yinghui Gao ◽  
Kaibing Kaibing Chen ◽  
Yan Gao ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Elderly Patients ◽  
Unstable Angina ◽  
Kaplan Meier ◽  
Obstructive Sleep ◽  
All Cause Mortality

Abstract BackgroundThe prognostic significance of obstructive sleep apnea (OSA) in elderly patients with type 2 diabetes is unclear. The aim of this study was to determine the risk of cardiovascular disease (CVD) and mortality in elderly patients with OSA complicated with type 2 diabetes compared to patients with OSA without type 2 diabetes.MethodsFrom January 2015 to October 2017, 1113 eligible elderly patients with OSA were enrolled in this consecutive multicentre prospective cohort study. An apnoea-hypopnoea index of ≥5 events per hour recorded by polysomnography was defined as the diagnostic criterion for OSA. We collected baseline demographics, clinical characteristics, sleep parameters and follow-up outcomes. The primary aim of this study was to determine the risk of incident major adverse cardiovascular events (MACE). Secondary outcomes were all-cause mortality, components of MACE and a composite of all events. Kaplan-Meier survival analysis and Cox proportional hazards models were used to evaluate whether type 2 diabetes was associated with incident events.ResultsA total of 266 (23.9%) patients had OSA complicated with type 2 diabetes. MACE occurred in 97 patients during the median 42-month follow-up. Kaplan-Meier survival curves indicated a significant relationship between OSA and MACE (log-rank P=0.003). Multivariable Cox regression analysis showed that type 2 diabetes increased the risk of MACE (HR=1.68, 95% CI:1.10-2.58, P=0.018), hospitalisation for unstable angina (HR=1.87, 95% CI:1.03-3.39, P=0.038) and a composite of all events in elderly patients with OSA (HR=1.72, 95% CI:1.12-2.64, P=0.012). However, there were no significant differences in the incidence of cardiovascular death, all-cause mortality, MI and hospitalisation for heart failure between patients with and without diabetes (P>0.05). The subgroup analysis demonstrated that females (AHR=2.50, 95% CI:1.15-5.43, P=0.021), ≥ 70 years (AHR=1.99, 95% CI:1.08-3.65, P=0.027), overweight and obese (AHR=1.75, 95% CI:1.10-2.80, P=0.019) with mild OSA (AHR=2.30, 95% CI: 1.01-5.26, P=0.49) were at a higher risk for MACE by diabetes.ConclusionOSA and type 2 diabetes are interrelated and synergistic with MACE, hospitalisation for unstable angina and a composite of all events development. Overweight and obese females, ≥ 70 years with mild OSA combined with type 2 diabetes presented a significantly high MACE risk.

scholarly journals The Ratio of Serum Eicosapentaenoic Acid to Arachidonic Acid Is Associated With Renal Impairment and Diabetic Macroangiopathies in Elderly Patients With Type 2 Diabetes: Figure 1

Diabetes Care ◽  
2013 ◽  
Vol 37 (1) ◽  
pp. e7-e8 ◽  
Author(s):  
Hiroyuki Ito ◽  
Hiroshi Ohira ◽  
Toshiya Chinen ◽  
Takashi Omoto ◽  
Masahiro Shinozaki ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Arachidonic Acid ◽  
Renal Impairment ◽  
Elderly Patients ◽  
Eicosapentaenoic Acid

scholarly journals Decreased systolic blood pressure is associated with increased risk of all-cause mortality in patients with type 2 diabetes and renal impairment: A nationwide longitudinal observational study of 27,732 patients based on the Swedish National Diabetes Register

2017 ◽  
Vol 14 (3) ◽  
pp. 226-235 ◽  
Author(s):  
Maria K Svensson ◽  
Henri Afghahi ◽  
Stefan Franzen ◽  
Staffan Björk ◽  
Soffia Gudbjörnsdottir ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Renal Impairment ◽  
Confidence Interval ◽  
Systolic Blood Pressure ◽  
Hazard Ratio ◽  
All Cause Mortality ◽  
Diabetes Register

Background: Previous studies have shown a U-shaped relationship between systolic blood pressure and risk of all-cause of mortality in patients with type 2 diabetes and renal impairment. Aims: To evaluate the associations between time-updated systolic blood pressure and time-updated change in systolic blood pressure during the follow-up period and risk of all-cause mortality in patients with type 2 diabetes and renal impairment. Patients and methods: A total of 27,732 patients with type 2 diabetes and renal impairment in the Swedish National Diabetes Register were followed for 4.7 years. Time-dependent Cox models were used to estimate risk of all-cause mortality. Time-updated mean systolic blood pressure is the average of the baseline and the reported post-baseline systolic blood pressures. Results: A time-updated systolic blood pressure < 130 mmHg was associated with a higher risk of all-cause mortality in patients both with and without a history of chronic heart failure (hazard ratio: 1.25, 95% confidence interval: 1.13–1.40 and hazard ratio: 1.26, 1.17–1.36, respectively). A time-updated decrease in systolic blood pressure > 10 mmHg between the last two observations was associated with higher risk of all-cause mortality (−10 to −25 mmHg; hazard ratio: 1.24, 95% confidence interval: 1.17–1.32). Conclusion: Both low systolic blood pressure and a decrease in systolic blood pressure during the follow-up are associated with a higher risk of all-cause mortality in patients with type 2 diabetes and renal impairment.

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