A drug utilization study of oral anticoagulants in five representative cities of China between 2015 and 2019

2021 ◽  
Author(s):  
Xiaojiao Gong ◽  
Qiuyi He ◽  
Jiajia Yan ◽  
Jie Chen ◽  
Xiao Chen ◽  
...  
Keyword(s):  
Drug Utilization ◽  
Oral Anticoagulants ◽  
Drug Utilization Study

scholarly journals Proton-pump inhibitors among adults: a nationwide drug-utilization study

2018 ◽  
Vol 11 ◽  
pp. 175628481877794 ◽  
Author(s):  
Óskar Ö. Hálfdánarson ◽  
Anton Pottegård ◽  
Einar S. Björnsson ◽  
Sigrún H. Lund ◽  
Margret H. Ogmundsdottir ◽  
...  
Keyword(s):  
Drug Utilization ◽  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Oral Anticoagulants ◽  
Population Based ◽  
Annual Incidence ◽  
Drug Utilization Study ◽  
Duration Of Treatment ◽  
Entire Study ◽  
Inflammatory Drugs

Background: The use of proton-pump inhibitors (PPIs) has grown worldwide, and there are concerns about increased unsubstantiated long-term use. The aim of the study was to describe the real-world use of PPIs over the past decade in an entire national population. Methods: This was a nationwide population-based drug-utilization study. Patterns of outpatient PPI use among adults in Iceland between 2003 and 2015 were investigated, including annual incidence and prevalence, duration of use, and dose of tablet used (lower versus higher), as well as the proportion of PPI use attributable to gastroprotection. Results: We observed 1,372,790 prescription fills over the entire study period, of which 95% were for higher-dose PPIs. Annual incidence remained stable across time (3.3–4.1 per 100 persons per year), while the annual prevalence increased from 8.5 per 100 persons to 15.5 per 100 persons. Prevalence increased with patient age and was higher among women than men. Duration of treatment increased with patients’ age (36% of users over 80 years remained on treatment after 1 year compared with 13% of users aged 19–39 years), and was longer among those initiating on a higher dose compared with a lower dose. The proportion of PPI users concurrently using nonsteroidal anti-inflammatory drugs decreased over the study period, while the proportion concurrently using acetylsalicylic acid, oral anticoagulants, or platelet inhibitors increased. Conclusions: In this nationwide study, a considerable increase in overall outpatient use of PPIs over a 13-year period was observed, particularly among older adults. Patients were increasingly treated for longer durations than recommended by clinical guidelines and mainly with higher doses.

A drug utilization study of oral hypoglycemic drugs and insulin in diabetic patients: Face to face with reality

2019 ◽  
Vol 11 (3) ◽  
pp. 25-29
Author(s):  
Suyog S Chopade ◽  
◽  
Rahul P Bhavsar ◽  
Devendra R Chaudhari ◽  
Bapurao M Bite ◽  
...  
Keyword(s):  
Drug Utilization ◽  
Diabetic Patients ◽  
Drug Utilization Study ◽  
Face To Face ◽  
Oral Hypoglycemic Drugs

scholarly journals Drug utilization study of antihypertensive drugs and prevalence of blood pressure control in adult hypertensive patients based on JNC VIII guidelines in a tertiary care hospital: a cross sectional study

2019 ◽  
Vol 8 (2) ◽  
pp. 245
Author(s):  
Saumya Ramadas ◽  
M. B. Sujatha ◽  
M. A. Andrews ◽  
Sanalkumar K. B.
Keyword(s):  
Blood Pressure ◽  
Combination Therapy ◽  
Drug Utilization ◽  
Antihypertensive Drug ◽  
Blood Pressure Control ◽  
Antihypertensive Drugs ◽  
Pressure Control ◽  
Antihypertensive Drug Therapy ◽  
Care Hospital ◽  
Drug Utilization Study

Background: Hypertension is a major independent risk factor for coronary artery disease, congestive heart failure, stroke, chronic kidney disease and peripheral vascular diseases if left untreated. Drug utilization study of antihypertensive drugs and the study on prevalence of blood pressure control would help in reducing the burden of the disease and health expenditure.Methods: The study was conducted in the Outpatient Department of Medicine in Government Medical College, Thrissur. Patients aged 18yrs or above diagnosed with hypertension, on antihypertensive drugs were enrolled in the study. Patients suffering from secondary hypertension and acutely ill were excluded. Patients were enrolled after taking an informed consent. Demographic data, present treatment for hypertension, associated co- morbid conditions if any, and treatment of the same were recorded. BP was recorded, and cost of treatment was calculated using CIMS.Results: A total of 250 patients were included in the study. Mono therapy was used in 64.8% patients and combination therapy in 35.2%. Overall drug utilization pattern showed that CCBs (42.8%) were most commonly prescribed, followed by ACEIs (32.4%) and ARBs (29.2%). Most commonly prescribed combination therapy was ACE I + BB (29.3%), followed by ARB + CCB (21.3%). Mean cost of antihypertensive drug therapy was 3057.8 Rs / yr. Recommended target BP was achieved in 49.6% of patients.Conclusions: The prescription pattern of antihypertensive drug was in accordance to the JNC-VIII guidelines. The blood pressure target was achieved only in less than 50% of patients.

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