scholarly journals A doggy tale: Risk of zoonotic infection with Bordetella bronchiseptica for cystic fibrosis (CF) patients from live licenced bacterial veterinary vaccines for cats and dogs

2021 ◽  
Author(s):  
John E. Moore ◽  
Jacqueline C. Rendall ◽  
Beverley C. Millar
Keyword(s):  
Cystic Fibrosis ◽  
Bordetella Bronchiseptica ◽  
Zoonotic Infection

scholarly journals Bordetella bronchiseptica in a Paediatric Cystic Fibrosis Patient: Possible Transmission from a Household Cat

2012 ◽  
Vol 59 (4) ◽  
pp. 246-250 ◽  
Author(s):  
K. B. Register ◽  
N. Sukumar ◽  
E. L. Palavecino ◽  
B. K. Rubin ◽  
R. Deora
Keyword(s):  
Cystic Fibrosis ◽  
Cystic Fibrosis Patient ◽  
Bordetella Bronchiseptica

scholarly journals Bordetella bronchiseptica in non-cystic fibrosis bronchiectasis

2018 ◽  
Vol 25 ◽  
pp. 187-188
Author(s):  
Elham Karamooz ◽  
Vanessa L. Yap ◽  
Alan F. Barker ◽  
Mark L. Metersky
Keyword(s):  
Cystic Fibrosis ◽  
Bordetella Bronchiseptica

scholarly journals Persistent Bordetella bronchiseptica infection in a child with cystic fibrosis: Relationship to bacterial phenotype

2015 ◽  
Vol 14 (5) ◽  
pp. E13-E15 ◽  
Author(s):  
Nevine El Khatib ◽  
Agnes Ferroni ◽  
Muriel Le Bourgeois ◽  
Frederique Chedevergne ◽  
Marlene Clairicia ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Bordetella Bronchiseptica

scholarly journals Bordetella bronchiseptica in a pediatric Cystic Fibrosis center

2014 ◽  
Vol 13 (1) ◽  
pp. 43-48 ◽  
Author(s):  
Cynthia Brady ◽  
Patricia Ackerman ◽  
Mahrya Johnson ◽  
John McNamara
Keyword(s):  
Cystic Fibrosis ◽  
Bordetella Bronchiseptica

scholarly journals Comparative Analyses of a Cystic Fibrosis Isolate of Bordetella bronchiseptica Reveal Differences in Important Pathogenic Phenotypes

2014 ◽  
Vol 82 (4) ◽  
pp. 1627-1637 ◽  
Author(s):  
Neelima Sukumar ◽  
Tracy L. Nicholson ◽  
Matt S. Conover ◽  
Tridib Ganguly ◽  
Rajendar Deora
Keyword(s):  
Cystic Fibrosis ◽  
Gene Expression Pattern ◽  
Infection Process ◽  
Bordetella Bronchiseptica ◽  
Zoonotic Transmission ◽  
Infection Model ◽  
Phenotypic Traits ◽  
Content Type ◽  
Cystic Fibrosis Isolate

ABSTRACTBordetella bronchisepticais a Gram-negative bacterium that infects and causes disease in a wide variety of animals.B. bronchisepticaalso infects humans, thereby demonstrating zoonotic transmission. An extensive characterization of humanB. bronchisepticaisolates is needed to better understand the distinct genetic and phenotypic traits associated with these zoonotic transmission events. Using whole-genome transcriptome and CGH analysis, we report that aB. bronchisepticacystic fibrosis isolate, T44625, contains a distinct genomic content of virulence-associated genes and differentially expresses these genes compared to the sequenced model laboratory strain RB50, a rabbit isolate. The differential gene expression pattern correlated with unique phenotypes exhibited by T44625, which included lower motility, increased aggregation, hyperbiofilm formation, and an increasedin vitrocapacity to adhere to respiratory epithelial cells. Using a mouse intranasal infection model, we found that although defective in establishing high bacterial burdens early during the infection process, T44625 persisted efficiently in the mouse nose. By documenting the unique genomic and phenotypic attributes of T44625, this report provides a blueprint for understanding the successful zoonotic potential ofB. bronchisepticaand other zoonotic bacteria.

Pregnancy in cystic fibrosis of the pancreas

JAMA ◽  
1966 ◽  
Vol 195 (12) ◽  
pp. 993-1000 ◽  
Author(s):  
R. J. Grand
Keyword(s):  
Cystic Fibrosis

Freeze-Fracture Examination of Tight Junctions of Human Eccrine Sweat Glands

1980 ◽  
Vol 38 ◽  
pp. 634-635
Author(s):  
J. V. Briggman ◽  
J. Bigelow ◽  
H. Bank ◽  
S. S. Spicer
Keyword(s):  
Cystic Fibrosis ◽  
Freeze Fracture ◽  
Sweat Glands ◽  
Hypertonic Solution ◽  
Dark Cells ◽  
Clear Cells ◽  
Junctional Complexes ◽  
Secretory Coil ◽  
Eccrine Sweat Glands ◽  
Eccrine Sweat

The prevalence of strands shown by freeze-fracture in the zonula occludens of junctional complexes is thought to correspond closely with the transepi-thelial electrical resistance and with the tightness of the junction and its obstruction to paracellular flow.1 The complexity of the network of junc¬tional complex strands does not appear invariably related to the degree of tightness of the junction, however, as rabbit ileal junctions have a complex network of strands and are permeable to lanthanum. In human eccrine sweat glands the extent of paracellular relative to transcellular flow remains unknown, both for secretion of the isotonic precursor fluid by the coil and for resorption of a hypertonic solution by the duct. The studies reported here undertook, therefore, to determine with the freeze-fracture technique the complexity of the network of ridges in the junctional complexes between cells in the secretory coil and the sweat ducts. Glands from a patient with cystic fibrosis were also examined because an alteration in junctional strands could underlie the decreased Na+ resorption by sweat ducts in this disease. Freeze-fracture replicas were prepared by standard procedures on isolated coil and duct segments of human sweat glands. Junctional complexes between clear cells, between dark cells and between clear and dark cells on the main lumen, and between clear cells on intercellular canaliculi of the coil con¬tained abundant anastomosing closely spaced strands averaging 6.4 + 0.7 (mean + SE) and 9.0 +0.5 (Fig. 1) per complex, respectively. Thus, the junctions in the intercellular canaliculi of the coil appeared comparable in complexity to those of tight epithlia. Occasional junctions exhibited, in addition, 2 to 5 widely spaced anastomosing strands in a very close network basal to the compact network. The fewer junctional complexes observed thus far between the superficial duct cells consisted on the average of 6 strands arranged in a close network and 1 to 4 underlying strands that lay widely separated from one another (Fig. 2). The duct epitelium would, thus, be judged slightly more "leaky" than the coil. Infrequent junctional complexes observed to date in the secretory coil segment of a cystic fibrosis specimen disclosed rela¬tively few closely crowded strands.

Chronic airway colonization by Penicillium emersonii in a patient with cystic fibrosis

1999 ◽  
Vol 37 (4) ◽  
pp. 291-293 ◽  
Author(s):  
B. Cimon ◽  
J. Carrere ◽  
J. P. Chazalette ◽  
J. F. Vinatier ◽  
D. Chabasse ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Airway Colonization ◽  
Chronic Airway
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