scholarly journals Comparative efficacy of Chinese herbal injections combined with azithromycin for mycoplasma pneumonia in children: A Bayesian network meta‐analysis of randomized controlled trials

2019 ◽  
Vol 44 (5) ◽  
pp. 675-684 ◽  
Author(s):  
Xiaojiao Duan ◽  
Kaihuan Wang ◽  
Jiarui Wu ◽  
Dan Zhang ◽  
Xinkui Liu ◽  
...  
Keyword(s):  
Bayesian Network ◽  
Randomized Controlled Trials ◽  
Meta Analysis ◽  
Controlled Trials ◽  
Comparative Efficacy ◽  
Randomized Controlled ◽  
Chinese Herbal ◽  
Mycoplasma Pneumonia

scholarly journals Comparative Efficacy of Chinese Herbal Injections for Treating Pediatric Bronchopneumonia: A Bayesian Network Meta-Analysis of Randomized Controlled Trials

2020 ◽  
Vol 2020 ◽  
pp. 1-12
Author(s):  
Xiaojiao Duan ◽  
Haojia Wang ◽  
Jiarui Wu ◽  
Yubo Guo ◽  
Kaihuan Wang ◽  
...  
Keyword(s):  
Randomized Controlled Trials ◽  
Western Medicine ◽  
Respiratory Diseases ◽  
Meta Analysis ◽  
Controlled Trials ◽  
Comparative Efficacy ◽  
Randomized Controlled ◽  
Chinese Herbal ◽  
Disappearance Time ◽  
The Common

Introduction. Pediatric bronchopneumonia is one of the common respiratory diseases in pediatrics. Chinese herbal injections (CHIs) are widely used to treat pediatric bronchopneumonia. In this study, we examined the efficacy of CHIs in the treatment of pediatric bronchopneumonia using a network meta-analysis (NMA). Methods. Randomized controlled trials (RCTs) of CHIs combined western medicine (WM) versus WM were searched from electronic databases. WinBUGS 1.4.3 and Stata 13.0 were adopted to compute calculations and prepare graphs, respectively. Results. 168 RCTs with 21917 patients were included. The results revealed that Xixinnao injection (XXN) + WM had the most probability to be the best intervention in the four aspects of rate of clinical efficacy, antipyretic time, cough disappearance time, and lung shadow disappearance time. While as to lung shadow disappearance time, asthma disappearance time, and hospitalization time, Yanhuning injection (YHN) + WM could be the best intervention. The safety of CHIs needs to be further assessed. Conclusions. Based on this NMA, XXN + WM and YHN + WM were potential optimal therapies in pediatric bronchopneumonia, and their safety should be strictly monitored.

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