scholarly journals Anticholinergic drug use and its association with self-reported symptoms among older persons with and without diabetes

2018 ◽  
Vol 44 (2) ◽  
pp. 229-235
Author(s):  
Niina-Mari Inkeri ◽  
Merja Karjalainen ◽  
Maija Haanpää ◽  
Hannu Kautiainen ◽  
Juha Saltevo ◽  
...  
Drugs & Aging ◽  
2017 ◽  
Vol 34 (10) ◽  
pp. 785-792 ◽  
Author(s):  
Benoit Cossette ◽  
Maimouna Bagna ◽  
Modou Sene ◽  
Caroline Sirois ◽  
Gabrielle P. Lefebvre ◽  
...  

1979 ◽  
Vol 9 (1) ◽  
pp. 5-26 ◽  
Author(s):  
David M. Petersen ◽  
Frank J. Whittington ◽  
Elizabeth T. Beer

There is no dearth of speculation about the use and misuse of drugs among older persons in American society. Scattered reports have indicated that the elderly increasingly use and misuse a wide variety of drugs, and in very recent years much public attention and concern has been directed toward this problem in the older population. Factual information, however, particularly incidence of use and factors related to elderly drug misuse, is scarce. This paper presents both a review of the relevant literature and a summation of available research evidence with particular reference to patterns of use of legal drugs, the types and extent of misuse of legal drugs, and the issue of illegal drug abuse by the elderly. Conclusions are provided as to what is known at this time regarding elderly drug use and misuse as well as some suggestions regarding future research that might contribute to an understanding of drug-using behavior among the elderly.


Medicina ◽  
2021 ◽  
Vol 57 (10) ◽  
pp. 1115
Author(s):  
Krzysztof Wilczyński ◽  
Marta Gorczyca ◽  
Jagna Gołębiowska ◽  
Jan Szewieczek

Background and Objectives: Anticholinergic drug use in the pharmacotherapy of elderly persons is common despite the increased risk of side effects. We examined the prevalence of anticholinergic drug use and total anticholinergic drug burden among patients admitted to an acute care geriatric ward in Poland. Materials and Methods: Cross-sectional study of 329 subjects hospitalized at the geriatric ward. Patient condition was assessed with a comprehensive geriatric assessment. The Anticholinergic Cognitive Burden (ACB) scale was used to estimate the total anticholinergic load. Results: Mean patient age was 79.61 ± 6.82 years. 40.73% of them were burdened with at least one anticholinergic drug. The clinically significant anticholinergic burden was observed in 13.98% of subjects. Patients with dementia, risk of falls, and severe disability had significantly higher total ACB scores compared to other groups. The receiver operating characteristics (ROC) curve revealed that the total ACB score ≥ 1 was significantly associated with dementia and the risk of falls. Total ACB score ≥ 2 was significantly associated with severe disability. Conclusions: Patients admitted to an acute care geriatric ward had an anticholinergic cognitive burden score comparable to other patient populations. We found associations at both low and elevated levels of anticholinergic burden with dementia and risk of falls. At elevated anticholinergic burden levels, we found associations with severe disability. Despite recommendations against the use of anticholinergics in older adults these medications are still commonly prescribed. Further study is necessary to define the characteristics of anticholinergic medication most closely associated with negative outcomes in elderly populations.


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