A case report describing a suspected rivaroxaban hypersensitivity reaction in a surgical patient

2012 ◽  
Vol 38 (2) ◽  
pp. 159-161 ◽  
Author(s):  
J. Yates ◽  
M. Choudhry ◽  
G. Keys
2021 ◽  
pp. 379-383
Author(s):  
Meghan L. McPhie ◽  
Kevin Y.M. Ren ◽  
J. Michael Hendry ◽  
Sonja Molin ◽  
Thomas Herzinger

Tattoos have become increasingly popular worldwide making adverse effects from tattoos a growing concern. In our report, we present a 51-year-old man who developed an unusual allergic reaction to the red ink portions of his tattoos that coincided with the initiation of ledipasvir/sofosbuvir treatment for his hepatitis C. Clinical and histological features were consistent with a delayed-type hypersensitivity reaction to red ink.


2009 ◽  
Vol 28 (2) ◽  
pp. 185-186 ◽  
Author(s):  
Simona Potenza ◽  
Guglielmo Nasti ◽  
Ottaiano Alessandro ◽  
Amelia Filippelli ◽  
Francesco Rossi ◽  
...  

2019 ◽  
Vol 47 (9) ◽  
pp. 4537-4543 ◽  
Author(s):  
Lu Li ◽  
Sujun Zheng ◽  
Yu Chen

We present the case report of a 6-year-old patient who developed Stevens–Johnson syndrome (SJS) and acute vanishing bile duct syndrome (VBDS) after taking oral amoxicillin and naproxen. SJS, an immune complex-mediated hypersensitivity reaction involving the skin and mucosa, is usually drug-induced, and it can lead to systemic symptoms. Acute VBDS is rare, often presenting with progressive loss of the intrahepatic biliary tract. VBDS is an immune-mediated bile duct-associated disease, and immunological damage to the bile duct system is an important mechanism for VBDS. Serious drug-induced liver injury (DILI) is also associated with immunity. The drug acts as a hapten with keratin on the surface of biliary epithelial cells. The autoantibodies produced by this action can damage the bile duct epithelial cells and cause the bile duct to disappear. SJS is a serious type of polymorphic erythema that is mainly considered to be a hypersensitivity reaction to drugs, and it may involve multiple factors.  The patient in this case report was treated with glucocorticoids, plasma exchange, ursodeoxycholic acid, and traditional Chinese medicine. He recovered completely within 5 months. This case report indicates that caution should be used because amoxicillin and naproxen can cause SJS and VBDS in children.


2020 ◽  
Vol 130 (2) ◽  
pp. 156-160.e1 ◽  
Author(s):  
Elli Anna Kotsailidi ◽  
Eleni-Marina Kalogirou ◽  
Dimitrios Michelogiannakis ◽  
Dimitrios Vlachodimitropoulos ◽  
Konstantinos I. Tosios

2020 ◽  
Vol 27 (1) ◽  
pp. 158-159
Author(s):  
Sarmad Al-Araji ◽  
Olga Ciccarelli

Serum sickness is a type III delayed hypersensitivity reaction which causes deposition of immune-complexes in the tissues. It has been reported with rituximab, and in this issue of the journal, there is a case report of a patient with relapsing remitting multiple sclerosis who developed a possible serum sickness after the third infusion of ocrelizumab. In this commentary, we discuss the current literature on serum sickness, and how to diagnose and manage it. We provide our opinion on this particular case, and encourage neurologists and patients to remain vigilant of such a possibility.


2013 ◽  
Vol 20 (Suppl 1) ◽  
pp. A208.1-A208
Author(s):  
M Geneste ◽  
S Bourget ◽  
P Brun ◽  
I Dufrene ◽  
H Hida

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