Enamel Matrix Derivative as an Adjunct to Minimally Invasive Non‐Surgical Treatment of Intrabony Defects: A randomized clinical trial

2021 ◽  
Author(s):  
Styliani Anoixiadou ◽  
Andreas Parashis ◽  
Ioannis Vouros
Keyword(s):  
Clinical Trial ◽  
Surgical Treatment ◽  
Minimally Invasive ◽  
Randomized Clinical Trial ◽  
Enamel Matrix Derivative ◽  
Enamel Matrix ◽  
Intrabony Defects ◽  
Non Surgical Treatment ◽  
Matrix Derivative

Enamel matrix derivative proteins for the treatment of proximal class II furcation involvements: a prospective 24-month randomized clinical trial

2010 ◽  
Vol 37 (12) ◽  
pp. 1100-1109 ◽  
Author(s):  
Renato Corrêa Viana Casarin ◽  
Érica Del Peloso Ribeiro ◽  
Francisco Humberto Nociti ◽  
Antônio Wilson Sallum ◽  
Gláucia Maria Bovi Ambrosano ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Class Ii ◽  
Enamel Matrix Derivative ◽  
Enamel Matrix ◽  
Matrix Derivative

Hydroxyapatite/β-tricalcium phosphate and enamel matrix derivative for treatment of proximal class II furcation defects: a randomized clinical trial

2013 ◽  
Vol 40 (3) ◽  
pp. 252-259 ◽  
Author(s):  
Maria F. S. Peres ◽  
Érica D. P. Ribeiro ◽  
Renato C. V. Casarin ◽  
Karina G. S. Ruiz ◽  
Francisco H. N. Junior ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Tricalcium Phosphate ◽  
Class Ii ◽  
Enamel Matrix Derivative ◽  
Enamel Matrix ◽  
Furcation Defects ◽  
Matrix Derivative

scholarly journals Two-year randomized clinical trial of enamel matrix derivative treated infrabony defects: radiographic analysis

2014 ◽  
Vol 14 (1) ◽  
Author(s):  
Mariana Schutzer Ragghianti Zangrando ◽  
Daniela Chambrone ◽  
Ivan Munhoz Pasin ◽  
Marina Clemente Conde ◽  
Cláudio Mendes Pannuti ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Enamel Matrix Derivative ◽  
Radiographic Analysis ◽  
Enamel Matrix ◽  
Infrabony Defects ◽  
Matrix Derivative

scholarly journals The role of surgical flap design (minimally invasive flap vs. extended flap with papilla preservation) on the healing of intrabony defects treated with an enamel matrix derivative: a 12-month two-center randomized controlled clinical trial

2021 ◽  
Author(s):  
Peter Windisch ◽  
Vincenzo Iorio-Siciliano ◽  
Daniel Palkovics ◽  
Luca Ramaglia ◽  
Andrea Blasi ◽  
...  
Keyword(s):  
Surgical Technique ◽  
Minimally Invasive ◽  
Test Group ◽  
Enamel Matrix Derivative ◽  
Control Group ◽  
Enamel Matrix ◽  
Intrabony Defects ◽  
Minimally Invasive Surgical ◽  
And Control ◽  
Matrix Derivative

Abstract Objectives Minimally invasive flap designs have been introduced to enhance blood clot stability and support wound healing. Limited data appear to suggest, that in intrabony defects, better clinical outcomes can be achieved by means of minimally invasive flap compared to more extended flaps. The aim of this study was to evaluate the healing of intrabony defects treated with either minimally invasive surgical flaps or with modified or simplified papilla preservation techniques in conjunction with the application of an enamel matrix derivative (EMD). Materials and methods Forty-seven subjects were randomly assigned to either test (N = 23) or control (N = 24) procedures. In the test group, the intrabony defects were accessed by means of either minimally invasive surgical technique (MIST) or modified minimally invasive surgical technique (M-MIST) according to the defect localization while the defects in the control group were treated with either the modified or simplified papilla preservation (MPP) or the simplified papilla preservation technique (SPP). EMD was used as regenerative material in all defects. The following clinical parameters were recorded at baseline and after 12 months: full-mouth plaque score (FMPS), full-mouth bleeding score (FMBS), probing depths (PD), clinical attachment level (CAL), and gingival recession (GR). Early healing index (EHI) score was assessed in both groups 1 week following the surgery. CAL gain was set as primary outcome. Results After 12 months follow-up, the CAL gain was 4.09 ± 1.68 mm in test group and 3.79 ± 1.67 mm in control group, while the PD reduction was 4.52 ± 1.34 mm and 4.04 ± 1.62 mm for test and control sites. In both groups, a minimal GR increase (0.35 ± 1.11 mm and 0.25 ± 1.03 mm) was noted. No residual PDs ≥ 6 mm were recorded in both groups. CAL gains of 4–5 mm were achieved in 30.4% and in 29.2% of test and control group, respectively. Moreover, CAL gains ≥ 6 mm were recorded in 21.7% of experimental sites and in 20.8% of control sites. No statistically significant differences in any of the evaluated parameters were found between the test and control procedures (P > 0.05). After 1 week post-surgery, a statistically significant difference (P < 0.05) between the groups was found in terms of EHI score. Conclusions Within the limits of this pilot RCT, the results have failed to show any differences in the measured parameters following treatment of intrabony defects with EMD, irrespective of the employed surgical technique. Clinical relevance In intrabony defects, the application of EMD in conjunction with either MIST/M-MIST or M-PPT/SPPT resulted in substantial clinical improvements.

Enamel matrix derivative effects on palatal mucosa wound healing: Randomized clinical trial

2021 ◽  
Author(s):  
Manuela Maria Viana Miguel ◽  
Ingrid Fernandes Mathias‐Santamaria ◽  
Amanda Rossato ◽  
Laís Fernanda Ferreira Ferraz ◽  
Thiago Perez Rangel ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Wound Healing ◽  
Randomized Clinical Trial ◽  
Enamel Matrix Derivative ◽  
Enamel Matrix ◽  
Palatal Mucosa ◽  
Matrix Derivative
Sign in / Sign up

Export Citation Format

Share Document