Occurrence and risk indicators of medication-related osteonecrosis of the jaw after dental extraction: a systematic review and meta-analysis

2015 ◽  
Vol 42 (10) ◽  
pp. 922-932 ◽  
Author(s):  
Elise Gaudin ◽  
Laurence Seidel ◽  
Miljana Bacevic ◽  
Eric Rompen ◽  
France Lambert
2016 ◽  
Vol 4;19 (4;5) ◽  
pp. 215-228 ◽  
Author(s):  
Mark J. Elzey

Background: Opioid overdose continues to be a significant and growing cause of preventable mortality and morbidity. Studies suggest that unintentional, non-fatal overdose from prescription opioid analgesics constitutes a large portion of total overdose events. The societal burden associated with these events is a frequently overlooked public health concern. Objectives: To evaluate unintentional, non-fatal prescription opioid overdoses, including the identification of risk factors, societal burden, and knowledge gaps where further study is warranted. Study Design: Systematic review of the literature for unintentional, non-fatal opioid overdose. Methods: Preferred reporting items for systematic reviews and meta-analyses guidelines were used in constructing this systematic review. To determine the scope of the existing literature, a systematic search was conducted using the MEDLINE, CINAHL, PsycINFO, and Web of Science databases. Results: This systematic review analyzes 24 articles (21 retrospective descriptive analyses, 2 prospective analyses, one phase III trial, and one meta-analysis). Articles were reviewed by authors and relevant data examined. Results show that opioid overdose morbidity is significantly more prevalent than mortality and sequelae of non-fatal events should be studied in more detail. Limitations: The limitations of this systematic review include the range of study populations and opioids discussed and the broad and variable definitions of “opioid overdose” in the literature. Conclusion(s): Opioid overdose morbidity and mortality is seen across the entire spectrum of inpatient and outpatient use with significant numbers of adverse events occurring in population segments not identified by high risk indicators. Increased physician awareness and a multi-modal approach could help mitigate the overdose epidemic while maintaining effective pain control for patients. Key words: Prescription, opioid, accidental drug overdose, unintentional overdose, drug poisoning, fentanyl, oxycodone, hydrocodone, methadone, oxymorphone, hydromorphone


Author(s):  
Akanksha Srivastava ◽  
Graciela M. Nogueras Gonzalez ◽  
Yimin Geng ◽  
Alexander M. Won ◽  
Maria E. Cabanillas ◽  
...  

Gerodontology ◽  
2019 ◽  
Vol 36 (4) ◽  
pp. 313-324 ◽  
Author(s):  
Shinichiro Kuroshima ◽  
Muneteru Sasaki ◽  
Hiroshi Murata ◽  
Takashi Sawase

2019 ◽  
Vol 49 (3) ◽  
pp. 190-200 ◽  
Author(s):  
Alejandro I. Lorenzo‐Pouso ◽  
Mario Pérez‐Sayáns ◽  
Cintia Chamorro‐Petronacci ◽  
Pilar Gándara‐Vila ◽  
Pía López‐Jornet ◽  
...  

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