scholarly journals Biodistribution of adeno‐associated virus type 2 carrying multi‐characteristic opsin in dogs following intravitreal injection

2021 ◽  
Vol 25 (18) ◽  
pp. 8676-8686
Author(s):  
Kissaou T. Tchedre ◽  
Subrata Batabyal ◽  
Melissa Galicia ◽  
Darryl Narcisse ◽  
Sourajit Mitra Mustafi ◽  
...  
Keyword(s):  
Intravitreal Injection ◽  
Virus Type ◽  
Adeno Associated Virus

Biologically active Rep proteins of adeno-associated virus type 2 produced as fusion proteins in Escherichia coli.

1994 ◽  
Vol 68 (2) ◽  
pp. 797-804 ◽  
Author(s):  
J A Chiorini ◽  
M D Weitzman ◽  
R A Owens ◽  
E Urcelay ◽  
B Safer ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Virus Type ◽  
Fusion Proteins ◽  
Biologically Active ◽  
Adeno Associated Virus ◽  
Rep Proteins

scholarly journals Adeno-Associated Virus Type 2 and Hepatocellular Carcinoma?

2015 ◽  
Vol 26 (12) ◽  
pp. 779-781 ◽  
Author(s):  
Kenneth I. Berns ◽  
Barry J. Byrne ◽  
Terence R. Flotte ◽  
Guangping Gao ◽  
William W. Hauswirth ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Virus Type ◽  
Adeno Associated Virus

Induction of an Antitumoral Immune Response by Wild-Type Adeno-Associated Virus Type 2 in an In Vivo Model of Pancreatic Carcinoma

Pancreas ◽  
2007 ◽  
Vol 35 (1) ◽  
pp. 63-72 ◽  
Author(s):  
Sven Eisold ◽  
Jan Schmidt ◽  
Eduard Ryschich ◽  
Michael Gock ◽  
Ernst Klar ◽  
...  
Keyword(s):  
Immune Response ◽  
Pancreatic Carcinoma ◽  
Virus Type ◽  
In Vivo Model ◽  
Wild Type ◽  
Adeno Associated Virus

scholarly journals Presence of atrs-Like Motif Promotes Rep-Mediated Wild-Type Adeno-Associated Virus Type 2 Integration

2015 ◽  
Vol 89 (14) ◽  
pp. 7428-7432 ◽  
Author(s):  
Karl Petri ◽  
Richard Gabriel ◽  
Leticia Agundez ◽  
Raffaele Fronza ◽  
Saira Afzal ◽  
...  
Keyword(s):  
Virus Type ◽  
Integration Site ◽  
Dermal Fibroblasts ◽  
Wild Type ◽  
Mobility Shift ◽  
Adeno Associated Virus ◽  
Rep Protein ◽  
Electrophoretic Mobility Shift Assays ◽  
First Time

High-throughput integration site (IS) analysis of wild-type adeno-associated virus type 2 (wtAAV2) in human dermal fibroblasts (HDFs) and HeLa cells revealed that juxtaposition of a Rep binding site (RBS) and terminal resolution site (trs)-like motif leads to a 4-fold-increased probability of wtAAV integration. Electrophoretic mobility shift assays (EMSAs) confirmed binding of Rep to off-target RBSs. For the first time, we show Rep protein off-target nicking activity, highlighting the importance of the nicking substrate for Rep-mediated integration.

scholarly journals Charge-to-Alanine Mutagenesis of the Adeno-Associated Virus Type 2 Rep78/68 Proteins Yields Temperature-Sensitive and Magnesium-Dependent Variants

2000 ◽  
Vol 74 (1) ◽  
pp. 591-591
Author(s):  
Denise K. Gavin ◽  
Samuel M. Young ◽  
Weidong Xiao ◽  
Brenda Temple ◽  
Corinne R. Abernathy ◽  
...  
Keyword(s):  
Virus Type ◽  
Temperature Sensitive ◽  
Adeno Associated Virus

scholarly journals Genetic modifications of the adeno-associated virus type 2 capsid reduce the affinity and the neutralizing effects of human serum antibodies

Gene Therapy ◽  
2003 ◽  
Vol 10 (26) ◽  
pp. 2139-2147 ◽  
Author(s):  
N A Huttner ◽  
A Girod ◽  
L Perabo ◽  
D Edbauer ◽  
J A Kleinschmidt ◽  
...  
Keyword(s):  
Human Serum ◽  
Virus Type ◽  
Serum Antibodies ◽  
Adeno Associated Virus ◽  
Genetic Modifications

scholarly journals Adeno-Associated Virus Type 2 Rep40 Modulates the Proliferation Rate of Rep52-Expressing HeLa Cells

Intervirology ◽  
2003 ◽  
Vol 46 (2) ◽  
pp. 127-134
Author(s):  
Donglan Li ◽  
Saburo Kashii ◽  
Toshiyuki Sahara ◽  
Kazuhiko Ito
Keyword(s):  
Virus Type ◽  
Hela Cells ◽  
Proliferation Rate ◽  
Adeno Associated Virus

scholarly journals Integrin αVβ5 Is Not Involved in Adeno-Associated Virus Type 2 (AAV2) Infection

Virology ◽  
1999 ◽  
Vol 264 (2) ◽  
pp. 436-440 ◽  
Author(s):  
Jianming Qiu ◽  
Kevin E. Brown
Keyword(s):  
Virus Type ◽  
Adeno Associated Virus
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