scholarly journals Asprin‐loaded strontium‐containing α‐calcium sulphate hemihydrate/nano‐hydroxyapatite composite promotes regeneration of critical bone defects

2020 ◽  
Vol 24 (23) ◽  
pp. 13690-13702
Author(s):  
Yi Jiang ◽  
Hanjun Qin ◽  
Haoyang Wan ◽  
Jun Yang ◽  
Qi Yu ◽  
...  
Keyword(s):  
Calcium Sulphate ◽  
Bone Defects ◽  
Hydroxyapatite Composite ◽  
Critical Bone Defects ◽  
Calcium Sulphate Hemihydrate

scholarly journals In VivoOsteogenesis of Vancomycin Loaded Nanohydroxyapatite/Collagen/Calcium Sulfate Composite for Treating Infectious Bone Defect Induced by Chronic Osteomyelitis

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Xiaojie Lian ◽  
Kezheng Mao ◽  
Xi Liu ◽  
Xiumei Wang ◽  
Fuzhai Cui
Keyword(s):  
Bone Graft ◽  
Bone Defect ◽  
Calcium Sulfate ◽  
Chronic Osteomyelitis ◽  
Rabbit Model ◽  
Calcium Sulphate ◽  
Bone Defects ◽  
Bone Graft Substitute ◽  
Calcium Sulphate Hemihydrate

A novel antibacterial bone graft substitute was developed to repair bone defects and to inhibit related infections simultaneously. This bone composite was prepared by introducing vancomycin (VCM) to nanohydroxyapatite/collagen/calcium sulphate hemihydrate (nHAC/CSH). XRD, SEM, and CCK-8 tests were used to characterize the structure and morphology and to investigate the adhesion and proliferation of murine osteoblastic MC3T3-E1 cell on VCM/nHAC/CSH composite. The effectiveness in restoring infectious bone defects was evaluatedin vivousing a rabbit model of chronic osteomyelitis. Ourin vivoresults implied that the VCM/nHAC/CSH composite performed well both in antibacterial ability and in bone regeneration. This novel bone graft substitute should be very promising for the treatment of bone defect-related infection in orthopedic surgeries.

The reactivity of calcium sulphate hemihydrate

1966 ◽  
Vol 16 (3) ◽  
pp. 78-80
Author(s):  
M. J. Ridge ◽  
H. Surkevicius
Keyword(s):  
Calcium Sulphate ◽  
Calcium Sulphate Hemihydrate

3D-printed Poly-Lactic Co-Glycolic Acid (PLGA) scaffolds in non-critical bone defects impede bone regeneration in rabbit tibia bone

2021 ◽  
pp. 1-7
Author(s):  
Jin Xi Lim ◽  
Min He ◽  
Alphonsus Khin Sze Chong
Keyword(s):  
Computed Tomography ◽  
Bone Regeneration ◽  
Bone Defect ◽  
Volume Ratio ◽  
Bone Defects ◽  
Control Group ◽  
Micro Computed Tomography ◽  
Rabbit Tibia ◽  
3D Printed ◽  
Critical Bone Defects

BACKGROUND: An increasing number of bone graft materials are commercially available and vary in their composition, mechanism of action, costs, and indications. OBJECTIVE: A commercially available PLGA scaffold produced using 3D printing technology has been used to promote the preservation of the alveolar socket after tooth extraction. We examined its influence on bone regeneration in long bones of New Zealand White rabbits. METHODS: 5.0-mm-diameter circular defects were created on the tibia bones of eight rabbits. Two groups were studied: (1) control group, in which the bone defects were left empty; (2) scaffold group, in which the PLGA scaffolds were implanted into the bone defect. Radiography was performed every two weeks postoperatively. After sacrifice, bone specimens were isolated and examined by micro-computed tomography and histology. RESULTS: Scaffolds were not degraded by eight weeks after surgery. Micro-computed tomography and histology showed that in the region of bone defects that was occupied by scaffolds, bone regeneration was compromised and the total bone volume/total volume ratio (BV/TV) was significantly lower. CONCLUSION: The implantation of this scaffold impedes bone regeneration in a non-critical bone defect. Implantation of bone scaffolds, if unnecessary, lead to a slower rate of fracture healing.

Osteoblast adherence and resorption activity of isolated osteoclasts on calcium sulphate hemihydrate

Biomaterials ◽  
1995 ◽  
Vol 16 (17) ◽  
pp. 1327-1332 ◽  
Author(s):  
M. Sidqui ◽  
P. Collin ◽  
C. Vitte ◽  
N. Forest
Keyword(s):  
Calcium Sulphate ◽  
Calcium Sulphate Hemihydrate

Hydration of Calcium Sulphate Hemihydrate

Nature ◽  
1964 ◽  
Vol 204 (4953) ◽  
pp. 70-71 ◽  
Author(s):  
M. J. RIDGE
Keyword(s):  
Calcium Sulphate ◽  
Calcium Sulphate Hemihydrate

The monoclinic I2 structure of bassanite, calcium sulphate hemihydrate (CaSO4 0.5H2O)

2001 ◽  
Vol 13 (5) ◽  
pp. 985-993 ◽  
Author(s):  
Paolo Ballirano ◽  
Adriana Maras ◽  
Simone Meloni ◽  
Ruggero Caminiti
Keyword(s):  
Calcium Sulphate ◽  
Calcium Sulphate Hemihydrate

Hydration of calcium sulphate hemihydrate. II. Acceleration by neutral salts

2007 ◽  
Vol 12 (6) ◽  
pp. 252-256 ◽  
Author(s):  
M. J. Ridge ◽  
H. Surkevicius ◽  
K. I. Lardner
Keyword(s):  
Calcium Sulphate ◽  
Calcium Sulphate Hemihydrate
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