scholarly journals Long noncoding RNA MALAT 1 enhances the docetaxel resistance of prostate cancer cells via miR‐145‐5p‐mediated regulation of AKAP 12

2018 ◽  
Vol 22 (6) ◽  
pp. 3223-3237 ◽  
Author(s):  
Dong Xue ◽  
Hao Lu ◽  
Han‐Yan Xu ◽  
Cui‐Xing Zhou ◽  
Xiao‐Zhou He
Keyword(s):  
Prostate Cancer ◽  
Cancer Cells ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Prostate Cancer Cells ◽  
Docetaxel Resistance

The function of long noncoding RNA HOTAIRM1 in the progression of prostate cancer cells

Andrologia ◽  
2020 ◽  
Author(s):  
Lei Wang ◽  
Longning Wang ◽  
Qingfen Wang ◽  
Bahman Yosefi ◽  
Sen Wei ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Cells ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Prostate Cancer Cells

Knockdown of long noncoding RNA AC245100.4 inhibits the tumorigenesis of prostate cancer cells via the STAT3/NR4A3 axis

Epigenomics ◽  
2021 ◽  
Author(s):  
Chi Liu ◽  
Ping Lin ◽  
Jiabin Zhao ◽  
Hui Xie ◽  
Rou Li ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Cells ◽  
Rna Sequencing ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Transcriptional Repressor ◽  
Sequencing Analysis ◽  
Loss Of Function ◽  
Prostate Cancer Cells ◽  
Rna Immunoprecipitation

Aim: To explore the role and mechanism of long noncoding RNA AC245100.4 and NR4A3 in prostate cancer (PCa). Methods: RNA-sequencing analysis was used to detect the downstream genes of AC245100.4. A series of gain- and loss-of-function approaches were used to investigate the roles of AC245100.4 and NR4A3. RNA immunoprecipitation was performed to examine the interaction between AC245100.4 and STAT3. Results: AC245100.4 was significantly upregulated in PCa cells and tissues. Knockdown of AC21500.4 significantly inhibited the tumorigenesis of PCa cells. Mechanistically, AC245100.4 deregulated the transcription of NR4A3 via increasing p-STAT3, which acted as a transcriptional repressor of NR4A3. Conclusion: Knockdown of lncRNA AC245100.4 inhibits the tumorigenesis of PCa cells via the STAT3/ NR4A3 axis.

scholarly journals Long noncoding RNA PCA3 regulates glycolysis, viability and apoptosis by mediating the miR-1/CDK4 axis in prostate cancer

RSC Advances ◽  
2018 ◽  
Vol 8 (66) ◽  
pp. 37564-37572 ◽  
Author(s):  
Shuo Gu ◽  
Xiaobing Niu ◽  
Fei Mao ◽  
Zongyuan Xu
Keyword(s):  
Prostate Cancer ◽  
Cancer Cells ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Aerobic Glycolysis ◽  
Prostate Cancer Cells

We proved that PCA3 regulated aerobic glycolysis, viability and apoptosis by regulating the miR-1/CDK4 axis in prostate cancer cells.

scholarly journals PCA3 long noncoding RNA modulates the expression of key cancer-related genes in LNCaP prostate cancer cells

Tumor Biology ◽  
2016 ◽  
Vol 37 (8) ◽  
pp. 11339-11348 ◽  
Author(s):  
Ana Emília Goulart Lemos ◽  
Luciana Bueno Ferreira ◽  
Nadia Maria Batoreu ◽  
Paula Priscilla de Freitas ◽  
Martin Hernan Bonamino ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Cells ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Prostate Cancer Cells

scholarly journals MicroRNA-181a promotes docetaxel resistance in prostate cancer cells

The Prostate ◽  
2017 ◽  
Vol 77 (9) ◽  
pp. 1020-1028 ◽  
Author(s):  
Cameron M. Armstrong ◽  
Chengfei Liu ◽  
Wei Lou ◽  
Alan P. Lombard ◽  
Christopher P. Evans ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Cells ◽  
Prostate Cancer Cells ◽  
Docetaxel Resistance
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