scholarly journals Aerobic exercise training rescues protein quality control disruption on white skeletal muscle induced by chronic kidney disease in rats

2017 ◽  
Vol 22 (3) ◽  
pp. 1452-1463 ◽  
Author(s):  
Wilson Max Almeida Monteiro De Moraes ◽  
Pamella Ramona Moraes de Souza ◽  
Nathalie Alves da Paixão ◽  
Luís Gustavo Oliveira de Sousa ◽  
Daniel Araki Ribeiro ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Chronic Kidney Disease ◽  
Quality Control ◽  
Kidney Disease ◽  
Exercise Training ◽  
Aerobic Exercise ◽  
Protein Quality ◽  
Protein Quality Control ◽  
Aerobic Exercise Training

scholarly journals Is aerobic exercise training during hemodialysis a reliable intervention for autonomic dysfunction in individuals with chronic kidney disease? A prospective longitudinal clinical trial

2019 ◽  
Vol Volume 12 ◽  
pp. 711-718 ◽  
Author(s):  
Mauro José de Deus Morais ◽  
Luiz Carlos de Abreu ◽  
Fabiano Santana de Oliveira ◽  
Italla Maria Pinheiro Bezerra ◽  
Rodrigo Daminello Raimundo ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Exercise Training ◽  
Aerobic Exercise ◽  
Autonomic Dysfunction ◽  
Aerobic Exercise Training ◽  
Prospective Longitudinal

scholarly journals Age-associated declines in mitochondrial biogenesis and protein quality control factors are minimized by exercise training

2012 ◽  
Vol 303 (2) ◽  
pp. R127-R134 ◽  
Author(s):  
Erika Koltai ◽  
Nikolett Hart ◽  
Albert W. Taylor ◽  
Sataro Goto ◽  
Jenny K. Ngo ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Quality Control ◽  
Exercise Training ◽  
Mitochondrial Biogenesis ◽  
Protein Quality ◽  
Mitochondrial Protein ◽  
Protein Quality Control ◽  
Treadmill Running ◽  
Common Finding ◽  
Moderate Intensity

A decline in mitochondrial biogenesis and mitochondrial protein quality control in skeletal muscle is a common finding in aging, but exercise training has been suggested as a possible cure. In this report, we tested the hypothesis that moderate-intensity exercise training could prevent the age-associated deterioration in mitochondrial biogenesis in the gastrocnemius muscle of Wistar rats. Exercise training, consisting of treadmill running at 60% of the initial V̇o2max, reversed or attenuated significant age-associated (detrimental) declines in mitochondrial mass (succinate dehydrogenase, citrate synthase, cytochrome- c oxidase-4, mtDNA), SIRT1 activity, AMPK, pAMPK, and peroxisome proliferator-activated receptor gamma coactivator 1-α, UCP3, and the Lon protease. Exercise training also decreased the gap between young and old animals in other measured parameters, including nuclear respiratory factor 1, mitochondrial transcription factor A, fission-1, mitofusin-1, and polynucleotide phosphorylase levels. We conclude that exercise training can help minimize detrimental skeletal muscle aging deficits by improving mitochondrial protein quality control and biogenesis.

scholarly journals Reductions in skeletal muscle mitochondrial mass are not restored following exercise training in patients with chronic kidney disease

2019 ◽  
Vol 34 (1) ◽  
pp. 1755-1767 ◽  
Author(s):  
Emma L. Watson ◽  
Luke A. Baker ◽  
Thomas J. Wilkinson ◽  
Douglas W. Gould ◽  
Matthew P.M. Graham‐Brown ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Exercise Training ◽  
Mitochondrial Mass
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