scholarly journals Matrix metalloproteinase inhibition attenuates right ventricular dysfunction and improves responses to dobutamine during acute pulmonary thromboembolism

2013 ◽  
Vol 17 (12) ◽  
pp. 1588-1597 ◽  
Author(s):  
Evandro M. Neto‐Neves ◽  
Ozelia Sousa‐Santos ◽  
Karina C. Ferraz ◽  
Elen Rizzi ◽  
Carla S. Ceron ◽  
...  
2012 ◽  
Vol 26 (S1) ◽  
Author(s):  
Evandro Manoel Neto Neves ◽  
Ozelia Sousa Santos ◽  
Karina Coutinho Ferraz ◽  
Carla Speroni Ceron ◽  
Minna Dias Romano ◽  
...  

2018 ◽  
Vol 24 (9_suppl) ◽  
pp. 56S-62S ◽  
Author(s):  
Murat Gök ◽  
Alparslan Kurtul ◽  
Murat Harman ◽  
Meryem Kara ◽  
Muhammed Süleymanoglu ◽  
...  

In this study, the association between the right ventricular dysfunction (RVD) and CHA2DS2-VASc (C: congestive heart failure or left ventricular systolic dysfunction, H: hypertension, A: age of ≥ 75 years, D: diabetes mellitus, S: previous stroke, V: vascular disease, A: age between 65 and 74 years, Sc: female gender) scores was investigated in patients with acute pulmonary thromboembolism (PTE). The patients have been assigned to 3 subgroups as massive, submassive, and nonmassive PTE. The CHA2DS2-VASc scores were calculated for all of the patients, and the scores have been classified into 3 groups as the scores between 0 and 1, the scores of 2, and the scores of 3 and over. The independent predictors of the RVD were investigated by the univariate and multivariate regression analyses. The independent predictors of the RVD were determined to be the CHA2DS2-VASc scores ( P = .034), the systolic pulmonary artery pressure ( P < .001), the presence of acute deep vein thrombosis ( P = .007), high simplified Pulmonary Embolism Severity Index ( P < .001), D-dimer ( P < .006), and the mean platelet volume ( P < .001). The CHA2DS2-VASc scores predicted the RVD with 70% sensitivity and 50% specificity as determined by the receiver operating characteristic analysis. The CHA2DS2-VASc score is an independent predictor of the RVD in patients with acute PTE.


2021 ◽  
Vol 55 (3/2021) ◽  
pp. 315-330
Author(s):  
ION ALEXANDRU CRISTIAN ◽  
BUSNATU ȘTEFAN ◽  
BADIU CRISTINEL DUMITRU ◽  
PARTAS-CIOLAN ROXANA-VIOLETA ◽  
SINESCU JULIETA ◽  
...  

2015 ◽  
Vol 17 (6) ◽  
pp. 293
Author(s):  
Edvin Prifti ◽  
Edmond Nuellari ◽  
Albana Doko

A 60-year-old woman was admitted due to massive bilateral pulmonary thromboembolism and entrapped thrombus in the patent foramen ovale and severe right ventricular dysfunction. The patient underwent on-pump/beating heart removal of the intracardiac thrombus and bilateral pulmonary embolectomy. The postoperative course was uneventful. The chosen surgical strategy seems to offer excellent outcome in patients with severe right ventricular dysfunction.


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