scholarly journals Mediation effect of obesity on the association between triglyceride‐glucose index and hyperuricemia in Chinese hypertension adults

2021 ◽  
Author(s):  
Jin Sun ◽  
Mingyan Sun ◽  
Yongkang Su ◽  
Man Li ◽  
Shouyuan Ma ◽  
...  
Keyword(s):  
Mediation Effect ◽  
Triglyceride Glucose Index

scholarly journals Mediation effect of obesity on the association between triglyceride-glucose index and hyperuricemia in Chinese hypertension adults.

2021 ◽  
Author(s):  
Jin Sun ◽  
Yongkang Su ◽  
Man Li ◽  
Shouyuan Ma ◽  
Yan Zhang ◽  
...  
Keyword(s):  
Fasting Blood Glucose ◽  
Surrogate Marker ◽  
Cross Sectional Study ◽  
Han Chinese ◽  
Mediation Effect ◽  
Cross Sectional ◽  
Tyg Index ◽  
Triglyceride Glucose Index ◽  
The Relationship

Abstract Background and Aims: The triglyceride glucose (TyG) index was regarded as a simple surrogate marker of insulin resistance (IR). It is confirmed that IR was significantly associated with hyperuricemia, and obesity was the risk factor for IR and hyperuricemia. However, the relationship between the TyG index and hyperuricemia and the potential role of obesity in Han Chinese hypertension are not entirely elucidated.Methods and Results： A community-based cross-sectional study was conducted in 4551 hypertension patients aged 40-75 years with clinical and biochemical data. The TyG index was calculated as ln [fasting triglyceride (mg/dl) × fasting blood glucose (mg/dl)/2]. Hyperuricemia was determined as serum uric acid ≥357μmol/L (6 mg/dl) for females and ≥417μmol/L (7 mg/dl) for males. The TyG index was higher in patients with hyperuricemia than in those without (8.99±0.61, 8.70±0.59, P<0.001). The prevalence of hyperuricemia in patients with the lowest (≤8.32), second (8.33-8.66), third (8.67-9.07) and the highest quartile (≥9.08) of the TyG index was 6.0%, 10.4%, 15.4%, 21.4%, respectively. Logistic regression analysis suggested that the higher quartile of TyG index was associated with increased hyperuricemia risk whether in crude or adjusted models (P<0.05). Mediation analysis showed that all of our obesity indexes partially mediated the association between the TyG index and hyperuricemia to some extent.Conclusion：TyG index is significantly associated with hyperuricemia in hypertension patients among Han Chinese, obesity plays a partial mediation role in this relationship.

scholarly journals Mediation Effect of Obesity on the Association Between Triglyceride-glucose Index and Hyperuricemia in Chinese Hypertension Adults.

2021 ◽  
Author(s):  
Jin Sun ◽  
Yongkang Su ◽  
Man Li ◽  
Shouyuan Ma ◽  
Yan Zhang ◽  
...  
Keyword(s):  
Fasting Blood Glucose ◽  
Surrogate Marker ◽  
Cross Sectional Study ◽  
Han Chinese ◽  
Mediation Effect ◽  
Cross Sectional ◽  
Tyg Index ◽  
Triglyceride Glucose Index ◽  
Relationship Of

Abstract Background: The triglyceride glucose (TyG) index was regarded as a simple surrogate marker of insulin resistance (IR). It is confirmed that IR was significantly associated with hyperuricemia, and obesity was the risk factor for IR and hyperuricemia. However, the relationship of TyG index and hyperuricemia and the potential role of obesity in Han Chinese hypertension are not entirely elucidated.Method：A community-based cross-sectional study was conducted in 4551 hypertension patients aged 40-75 years with clinical and biochemical data. The TyG index was calculated as ln [fasting triglyceride (mg/dl) × fasting blood glucose (mg/dl)/2]. Hyperuricemia was determined as serum uric acid ≥357μmol/L (6 mg/dl) for females and ≥417μmol/L (7 mg/dl) for males. Body mass index (BMI), waist (WC) and hip circumference (HC) were regarded as obesity indexes, to evaluate the mediation effect of the association between TyG index and hyperuricemia.Result：The TyG index was higher in patients with hyperuricemia than in those without (8.99±0.61, 8.70±0.59, P<0.001). The prevalence of hyperuricemia in patients with the lowest (≤8.32), second (8.33-8.66), the third (8.67-9.07) and the highest quartile (≥9.08) of TyG index was 6.0%, 10.4%, 15.4%, 21.4%, respectively. Logistic regression analysis suggested that the higher quartile of TyG index were associated with increased hyperuricemia risk whether in crude or adjusted models (P<0.05). Mediation analysis showed that all of our obesity indexes partially mediated the association between TyG index and hyperuricemia to some extent.Conclusion：TyG index is significantly associated with hyperuricemia in hypertension patients among Han Chinese, obesity plays a partial mediation role in this relationship.

Men’s Hunger, Food Consumption, and Preferences for Female Body Types

2014 ◽  
Vol 45 (6) ◽  
pp. 495-497 ◽  
Author(s):  
Nicolas Guéguen
Keyword(s):  
Food Consumption ◽  
Female Body ◽  
The Body ◽  
Slender Body ◽  
Mediation Effect ◽  
Point Scale ◽  
Body Type ◽  
Experimental Conditions

Nelson and Morrison (2005 , study 3) reported that men who feel hungry preferred heavier women. The present study replicates these results by using real photographs of women and examines the mediation effect of hunger scores. Men were solicited while entering or leaving a restaurant and asked to report their hunger on a 10-point scale. Afterwards, they were presented with three photographs of a woman in a bikini: One with a slim body type, one with a slender body type, and one with a slightly chubby body. The participants were asked to indicate their preference. Results showed that the participants entering the restaurant preferred the chubby body type more while satiated men preferred the thinner or slender body types. It was also found that the relation between experimental conditions and the choices of the body type was mediated by men’s hunger scores.

Linking LMX to Performance via Engagement: Moderated Mediation Effect

2011 ◽  
Author(s):  
Fangyi Liao ◽  
Liu-Qin Yang ◽  
Mo Wang ◽  
Junqi Shi
Keyword(s):  
Moderated Mediation ◽  
Mediation Effect
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