scholarly journals Age‐related alterations in cardiac and arterial structure and function in hypertensive women and men

Author(s):  
Anping Cai ◽  
Dan Zhou ◽  
Lin Liu ◽  
Yingling Zhou ◽  
Songtao Tang ◽  
...  
1998 ◽  
Vol 18 (7) ◽  
pp. 1149-1156 ◽  
Author(s):  
Barry P. McGrath ◽  
Yu-Lu Liang ◽  
Helena Teede ◽  
Louise M. Shiel ◽  
James D. Cameron ◽  
...  

2008 ◽  
Vol 65 (6) ◽  
pp. 412-419 ◽  
Author(s):  
R Schutte ◽  
T Nawrot ◽  
T Richart ◽  
L Thijs ◽  
H A Roels ◽  
...  

2007 ◽  
Vol 28 (2) ◽  
pp. 277-291 ◽  
Author(s):  
Wen-Bin He ◽  
Jun-Long Zhang ◽  
Jin-Feng Hu ◽  
Yun Zhang ◽  
Takeo Machida ◽  
...  

Oncotarget ◽  
2016 ◽  
Vol 7 (8) ◽  
pp. 8532-8545 ◽  
Author(s):  
Ahmed S. Ibrahim ◽  
Suchreet Mander ◽  
Khaled A. Hussein ◽  
Nehal M. Elsherbiny ◽  
Sylvia B. Smith ◽  
...  

2001 ◽  
Vol 37 (1) ◽  
pp. 224-230 ◽  
Author(s):  
Mark A Sader ◽  
Kaye A Griffiths ◽  
Robyn J McCredie ◽  
David J Handelsman ◽  
David S Celermajer

2017 ◽  
pp. 1576-1617
Author(s):  
Charis Styliadis ◽  
Panagiotis Kartsidis ◽  
Evangelos Paraskevopoulos

Advances in the field of neuroimaging have allowed for the examination of the effects of age-related changes on cognitive capacity in elderly populations. Structural techniques are now routinely used to report cortical atrophic rates in aging and particularly within the context of the Alzheimer's disease, and may be integrated with functional techniques which examine the functional characteristics of the cortex at rest and during the performance of a task. Despite advancing age cognitive function remains highly plastic, allowing for interventions that aim to maintain or even remediate its capacity and the mechanisms by which structure and function are altered among seniors. Overall, information on the integrity of the cerebral structure and function aid in the early detection and treatment of the Alzheimer's disease as well as the evaluation and track of the disease's progression. In this chapter, neuroimaging methods are presented along with findings that are particularly relevant for the study of neuroplasticity in the aging brain.


2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Monika Hunjadi ◽  
Claudia Lamina ◽  
Patrick Kahler ◽  
Tamara Bernscherer ◽  
Jorma Viikari ◽  
...  

Abstract The atherogenic process begins already in childhood and progresses to symptomatic condition with age. We investigated the association of cholesterol efflux capacity (CEC) and vascular markers of subclinical atherosclerosis in healthy, young adults. CEC was determined in 2282 participants of the Young Finns study using cAMP treated 3H-cholesterol-labeled J774 cells. The CEC was correlated to baseline and 6-year follow-up data of cardiovascular risk factors and ultrasound measurements of arterial structure and function. CEC was higher in women, correlated with total cholesterol, HDL-C, and apolipoprotein A-I, but not with LDL-C or apolipoprotein B. Compared to the lowest CEC quartile, the highest CEC quartile was significantly associated with high CRP levels and inversely associated with adiponectin. At baseline, high CEC was associated with decreased flow-mediated dilation (FMD) and carotid artery distensibility, as well as an increased Young's modulus of elasticity, indicating adverse changes in arterial structure, and function. The association reversed with follow-up FMD data, indicating the interaction of preclinical parameters over time. A higher CEC was directly associated with a lower risk of subclinical atherosclerosis at follow-up. In young and healthy subjects, CEC was associated with important lipid risk parameters at baseline, as in older patients and CAD patients, but inversely with early risk markers for subclinical atherosclerosis.


Sign in / Sign up

Export Citation Format

Share Document