scholarly journals Factors associated with incidence of stroke and heart failure among people living with HIV in Ghana: Evaluating Vascular Event Risk while on Long‐Term Antiretroviral Suppressive Therapy (EVERLAST) Study

Author(s):  
Fred Stephen Sarfo ◽  
Betty Norman ◽  
Lambert Appiah ◽  
Bruce Ovbiagele
2019 ◽  
Vol 15 ◽  
pp. 100189 ◽  
Author(s):  
Fred Stephen Sarfo ◽  
Michelle Nichols ◽  
Mulugeta Gebregziabher ◽  
Raelle Tagge ◽  
Shadrack Osei Asibey ◽  
...  

AIDS Care ◽  
2021 ◽  
pp. 1-3
Author(s):  
Maria Mazzitelli ◽  
Branca Isabel Pereira ◽  
Graeme Moyle ◽  
David Asboe ◽  
Anton Pozniak ◽  
...  

2020 ◽  
Vol 23 ◽  
pp. S570
Author(s):  
E. Foglia ◽  
B. Menzaghi ◽  
G. Rizzardini ◽  
E. Garagiola ◽  
L.B. Ferrario ◽  
...  

2021 ◽  
Author(s):  
Lisa Van de Wijer ◽  
Wouter van der Heijden ◽  
Mike van Verseveld ◽  
Mihai Netea ◽  
Quirijn de Mast ◽  
...  

AbstractContradictory data have been reported concerning neuropsychiatric side effects of the first-line antiretroviral drug dolutegravir, which may be partly due to lack of control groups or psychiatric assessment tools. Using validated self-report questionnaires, we compared mood and anxiety (DASS-42), impulsivity (BIS-11), and substance use (MATE-Q) between dolutegravir-treated and dolutegravir-naive people living with HIV (PLHIV). We analyzed 194, mostly male, PLHIV on long-term treatment of whom 82/194 (42.3%) used dolutegravir for a median (IQR) of 280 (258) days. Overall, 51/194 (26.3%) participants reported DASS-42 scores above the normal cut-off, 27/194 (13.5%) were classified as highly impulsive, and 58/194 (29.9%) regularly used recreational drugs. Regular substance use was positively associated with depression (p = 0.012) and stress scores (p = 0.045). We observed no differences between dolutegravir-treated and dolutegravir-naive PLHIV. Our data show that depressed and anxious moods and impulsivity are common in PLHIV and associate with substance use and not with dolutegravir use.


2017 ◽  
Vol 31 (1) ◽  
pp. 109-138 ◽  
Author(s):  
Mark J. Siedner

Objective: The number of people living with HIV (PLWH) over 50 years old in sub-Saharan Africa is predicted to triple in the coming decades, to 6-10 million. Yet, there is a paucity of data on the determinants of health and quality of life for older PLWH in the region. Methods: A review was undertaken to describe the impact of HIV infection on aging for PLWH in sub-Saharan Africa. Results: We (a) summarize the pathophysiology and epidemiology of aging with HIV in resource-rich settings, and (b) describe how these relationships might differ in sub-Saharan Africa, (c) propose a conceptual framework to describe determinants of quality of life for older PLWH, and (d) suggest priority research areas needed to ensure long-term gains in quality of life for PLWH in the region. Conclusions: Differences in traditional, lifestyle, and envirnomental risk factors, as well as unique features of HIV epidemiology and care delivery appear to substantially alter the contribution of HIV to aging in sub-Saharan Africa. Meanwhile, unique preferences and conceptualizations of quality of life will require novel measurement and intervention tools. An expanded research and public health infrastructure is needed to ensure that gains made in HIV prevention and treamtent are translated into long-term benefits in this region.


AIDS Care ◽  
2018 ◽  
Vol 31 (7) ◽  
pp. 885-892
Author(s):  
Sarah Kesselring ◽  
Charles Osborne ◽  
Andrea Bever ◽  
Kate Salters ◽  
Zishan Cui ◽  
...  

AIDS Care ◽  
2017 ◽  
Vol 29 (8) ◽  
pp. 1074-1078 ◽  
Author(s):  
Nuno Nobre ◽  
Marco Pereira ◽  
Risto P. Roine ◽  
Harri Sintonen ◽  
Jussi Sutinen

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