scholarly journals Nocturnal dipping status and the association of morning blood pressure surge with subclinical target organ damage in untreated hypertensives

2019 ◽  
Vol 21 (9) ◽  
pp. 1286-1294 ◽  
Author(s):  
Shenzhen Gong ◽  
Kai Liu ◽  
Runyu Ye ◽  
Jiangbo Li ◽  
Changqiang Yang ◽  
...  
2011 ◽  
Vol 29 ◽  
pp. e443
Author(s):  
A. Prejbisz ◽  
K. Jozwik-Plebanek ◽  
E. Florczak ◽  
M. Makowiecka-Ciesla ◽  
B. Pucilowska-Jankowska ◽  
...  

2019 ◽  
Vol 104 (11) ◽  
pp. 5170-5180 ◽  
Author(s):  
Ondřej Petrák ◽  
Ján Rosa ◽  
Robert Holaj ◽  
Branislav Štrauch ◽  
Zuzana Krátká ◽  
...  

Abstract Context Impaired diurnal blood pressure (BP) variability is related to higher cardiovascular risk. Objective To assess diurnal variability of BP and its relation to target organ damage (TOD) and catecholamine phenotype in a consecutive sample of pheochromocytoma/paraganglioma (PPGL). Design We included 179 patients with PPGL All patients underwent 24 hours of ambulatory BP monitoring to determine dipping status. Differences in plasma metanephrine or urine adrenaline were used to distinguish catecholamine biochemical phenotype. To evaluate TOD, renal functions, presence of left ventricle hypertrophy (LVH), and the subgroup (n = 111) carotid-femoral pulse wave velocity (PWV) were assessed. Structural equation modeling was used to find the relationship among nocturnal dipping, catecholamine phenotype, and TOD parameters. Results According to the nocturnal dipping, patients were divided into the three groups: dippers (28%), nondippers (40%), and reverse dippers (32%). Reverse dippers were older (P < 0.05), with a higher proportion of noradrenergic (NA) phenotype (P < 0.05), a higher prevalence of diabetes mellitus (P < 0.05), and sustained arterial hypertension (P < 0.01) and its duration (P < 0.05), as opposed to the other groups. All parameters of TOD were more pronounced only in reverse dippers compared with nondippers and dippers. The presence of NA phenotype (=absence of adrenaline production) was associated with reverse dipping and TOD (LVH and PWV). Conclusions Patients with reverse dipping had more substantial TOD compared with other groups. The NA phenotype plays an important role, not only in impaired diurnal BP variability but also independently from dipping status in more pronounced TOD of heart and vessels.


2019 ◽  
Vol 37 (7) ◽  
pp. 1427-1436 ◽  
Author(s):  
Runyu Ye ◽  
Kai Liu ◽  
Shenzhen Gong ◽  
Jiangbo Li ◽  
Ying Xu ◽  
...  

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