scholarly journals Gender‐Specific Outcomes after Percutaneous Left Atrial Appendage Closure ‐ A Nationwide Readmission Database Analysis

2022 ◽  
Author(s):  
Neel Patel ◽  
Sagar Ranka ◽  
Adrija Hajra ◽  
Dhrubajyoti Bandyopadhyay ◽  
Birendra Amgai ◽  
...  
Keyword(s):  
Left Atrial ◽  
Left Atrial Appendage ◽  
Atrial Appendage ◽  
Left Atrial Appendage Closure ◽  
Database Analysis ◽  
Nationwide Readmission Database ◽  
Gender Specific

Gender-specific differences in patients who underwent left atrial appendage closure

2021 ◽  
Author(s):  
Issameddine Ajmi ◽  
Steffen Schnupp ◽  
Majdi Amami ◽  
Christian Mahnkopf
Keyword(s):  
Left Atrial ◽  
Left Atrial Appendage ◽  
Oral Anticoagulants ◽  
Self Care ◽  
Female Gender ◽  
Atrial Appendage ◽  
Health State ◽  
Left Atrial Appendage Closure ◽  
Gender Specific Differences ◽  
Gender Specific

Aim: We aimed to study gender-specific differences in patients who underwent left atrial appendage closure (LAAC). Materials & methods: A total of 201 consecutive patients who underwent LAAC were enrolled. The EQ-5D-3L questionnaire was employed before and 3 months post-LAAC to study the quality of life. Results: Women had a higher score for Anxiety/Depression before implantation. Three months after LAAC, both groups showed a significant improvement in mobility, self-care and usual activities. The female gender had a significant improvement in health state 3 months after implantation than their male counterparts. Conclusion: Our data shows an improvement in mobility, self-care, usual activities and the overall health state in all patients after LAAC. This potential improvement, most likely caused by the discontinuation of oral anticoagulants, should be considered an indication for LAAC.

scholarly journals Gender-Specific Outcomes after Percutaneous Left Atrial Appendage Closure - A Nationwide Readmission Database Analysis

2021 ◽  
Author(s):  
Neel Patel ◽  
Sagar Ranka ◽  
Adrija Hajra ◽  
Dhrubajyoti Bandyopadhyay ◽  
Birendra Amgai ◽  
...  
Keyword(s):  
Left Atrial ◽  
Left Atrial Appendage ◽  
Cox Regression ◽  
Atrial Appendage ◽  
Regression Analyses ◽  
Left Atrial Appendage Closure ◽  
Major Bleed ◽  
Procedural Complications ◽  
Accuracy Of Results ◽  
Nationwide Readmission Database

Background: Thromboembolism-associated stroke is the most feared complication of Atrial fibrillation (AF). Percutaneous left atrial appendage closure (pLAAC) is indicated for stroke prevention in patients with AF who can’t tolerate long-term anticoagulation. We aim to study gender differences in peri-procedural and readmissions outcomes in pLAAC patients. Methods: Using the national readmission database from January 2016 to December 2018, AF patients undergoing the pLAAC procedure were identified. We used multivariate logistic regression analyses and time-to-event Cox regression analyses to conduct the study. Propensity matching with the Greedy method was done for the accuracy of results. Result: 28,819 patients were included in our study. Among them 11,946 (41.5%) were women and 16,873 (58.6%) were men. The mean age of overall population was 76.1 ± 8.5 years, with women ~ 1 year older than men. The overall rate of complications was higher in women (8.6% vs 6.6%, P<0.001), primarily driven by bleeding-related complications i.e., Major bleed (OR: 1.32 95% CI: 1.03-1.69, p=0.029), blood transfusion (OR: 1.45, 95% CI: 1.06-1.97, p=0.019) and cardiac tamponade (OR: 1.80, 95% CI: 1.13-2.89, p=0.014). Women had two times higher peri-procedural ischemic stroke. There was no difference in peri-procedural mortality. Women remained at 20% and 13% higher risk for readmission at 30 days and 6 months of discharge. Conclusion: Women had higher peri-procedural complications and were at higher risk of readmissions at 30 days and six months. However, there was no difference in mortality during the index hospitalization. Further studies are necessary to determine causality.

scholarly journals RCA THROMBOEMBOLISM FOLLOWING LEFT ATRIAL APPENDAGE CLOSURE

2021 ◽  
Vol 77 (18) ◽  
pp. 2486
Author(s):  
Ravi A. Thakker ◽  
Abraham Lee ◽  
Benjamin Greiner ◽  
Lin Gao ◽  
Masood Ahmad ◽  
...  
Keyword(s):  
Left Atrial ◽  
Left Atrial Appendage ◽  
Atrial Appendage ◽  
Left Atrial Appendage Closure
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