Efficacy and Tolerability of Quinidine as Salvage Therapy for Monomorphic Ventricular Tachycardia in patients with Structural Heart Disease

2021 ◽  
Author(s):  
Amrish Deshmukh ◽  
John Larson ◽  
Michael Ghannam ◽  
Mohammed Saeed ◽  
Ryan Cunnane ◽  
...  
Keyword(s):  
Heart Disease ◽  
Ventricular Tachycardia ◽  
Salvage Therapy ◽  
Structural Heart Disease ◽  
Monomorphic Ventricular Tachycardia

Sustained monomorphic ventricular tachycardia: the role of catheter ablation

ESC CardioMed ◽  
2018 ◽  
pp. 2279-2288
Author(s):  
Tilman Maurer ◽  
William G. Stevenson ◽  
Karl-Heinz Kuck
Keyword(s):  
Heart Disease ◽  
Ventricular Tachycardia ◽  
Catheter Ablation ◽  
Sudden Cardiac Death ◽  
Cardiac Death ◽  
Therapeutic Option ◽  
Structural Heart Disease ◽  
Premature Ventricular Contractions ◽  
Monomorphic Ventricular Tachycardia ◽  
Premature Beats

Monomorphic ventricular tachycardia (VT) may occur in the presence or absence of structural heart disease. The standard therapy for patients with structural heart disease at high risk of sudden cardiac death due to VT is the implantable cardioverter defibrillator (ICD). While ICDs effectively terminate VT and prevent sudden cardiac death, they do not prevent recurrent episodes of VT, since the underlying arrhythmogenic substrate remains unchanged. However, shocks from an ICD increase mortality and impair quality of life. These limitations as well as continuous advancements in technology have made catheter ablation an important treatment strategy for patients with structural heart disease presenting with VT. Idiopathic ventricular arrhythmias include premature ventricular contractions and VT occurring in the absence of overt structural heart disease. In this setting, catheter ablation has evolved as the primary therapeutic option for symptomatic ventricular premature beats and sustained VTs and is curative in most cases. This chapter presents an overview of the principles of invasive diagnosis and treatment of monomorphic VTs in patients with and without structural heart disease and delineates the clinical outcome of catheter ablation. Finally, the chapter provides an outlook to the future, discussing potential directions and upcoming developments in the field of catheter ablation of monomorphic VT.

Sustained monomorphic ventricular tachycardia associated with structural heart disease: classification, assessment, and initial treatment

ESC CardioMed ◽  
2018 ◽  
pp. 2265-2270
Author(s):  
Fernando M. Contreras-Valdes ◽  
Peter J. Zimetbaum
Keyword(s):  
Heart Disease ◽  
Ventricular Tachycardia ◽  
Sudden Death ◽  
Beta Blockers ◽  
Substantial Reduction ◽  
Structural Heart Disease ◽  
Disease Classification ◽  
Implantable Cardioverter Defibrillators ◽  
Monomorphic Ventricular Tachycardia ◽  
Cardioverter Defibrillators

Sustained monomorphic ventricular tachycardia occurs in patients with structural heart disease and may lead to syncope, haemodynamic collapse, or sudden death. The diagnosis is established by the electrocardiogram, with cardiac imaging used to determine the underlying substrate. Initial management requires a combination of electrical cardioversion and antiarrhythmic drugs, mainly amiodarone and beta blockers. Nonetheless, implantable cardioverter defibrillators provide the most substantial reduction in sudden death, with catheter ablation becoming an increasingly favoured strategy to minimize shocks and possibly lower mortality from ventricular arrhythmias in this population.

scholarly journals Mechanisms and Clinical Management of Ventricular Arrhythmias following Blunt Chest Trauma

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Daniel H. Wolbrom ◽  
Aleef Rahman ◽  
Cory M. Tschabrunn
Keyword(s):  
Heart Disease ◽  
Ventricular Tachycardia ◽  
Ventricular Arrhythmias ◽  
Blunt Chest Trauma ◽  
Chest Trauma ◽  
Motor Vehicle ◽  
Structural Heart Disease ◽  
Chest Injury ◽  
Chronic Stage ◽  
Chest Wall Injury

Nonpenetrating, blunt chest trauma is a serious medical condition with varied clinical presentations and implications. This can be the result of a dense projectile during competitive and recreational sports but may also include other etiologies such as motor vehicle accidents or traumatic falls. In this setting, the manifestation of ventricular arrhythmias has been observed both acutely and chronically. This is based on two entirely separate mechanisms and etiologies requiring different treatments. Ventricular fibrillation can occur immediately after chest wall injury (commotio cordis) and requires rapid defibrillation. Monomorphic ventricular tachycardia can develop in the chronic stage due to underlying structural heart disease long after blunt chest injury. The associated arrhythmogenic tissue may be complex and provides the necessary substrate to form a reentrant VT circuit. Ventricular tachycardia in the absence of overt structural heart disease appears to be focal in nature with rapid termination during ablation. Regardless of the VT mechanism, patients with recurrent episodes, despite antiarrhythmic medication in the chronic stage following blunt chest injury, are likely to require ablation to achieve VT control. This review article will describe the mechanisms, pathophysiology, and treatment of ventricular arrhythmias that occur in both the acute and chronic stages following blunt chest trauma.

scholarly journals Combined Endocardial-Epicardial Versus Endocardial Catheter Ablation Alone for Ventricular Tachycardia in Structural Heart Disease

2019 ◽  
Vol 5 (1) ◽  
pp. 13-24 ◽  
Author(s):  
Jorge Romero ◽  
Roberto C. Cerrud-Rodriguez ◽  
Luigi Di Biase ◽  
Juan Carlos Diaz ◽  
Isabella Alviz ◽  
...  
Keyword(s):  
Heart Disease ◽  
Ventricular Tachycardia ◽  
Catheter Ablation ◽  
Structural Heart Disease

scholarly journals Management of ventricular tachycardia storm in patients with structural heart disease

2017 ◽  
Vol 9 (6) ◽  
pp. 521 ◽  
Author(s):  
Daniele Muser ◽  
Pasquale Santangeli ◽  
Jackson J Liang
Keyword(s):  
Heart Disease ◽  
Ventricular Tachycardia ◽  
Structural Heart Disease

scholarly journals Is the time domain signal-averaged electrocardiogram helpful in patients with ventricular tachycardia without apparent structural heart disease?

1995 ◽  
Vol 18 (10) ◽  
pp. 568-572 ◽  
Author(s):  
Yelena S. K. Orlov ◽  
Michael A. Brodsky ◽  
Michael V. Orlov ◽  
Byron J. Allen ◽  
Rex J. Winters
Keyword(s):  
Heart Disease ◽  
Ventricular Tachycardia ◽  
Time Domain ◽  
Structural Heart Disease ◽  
Time Domain Signal ◽  
The Time Domain

Short Term Variability of Repolarization Predicts Ventricular Tachycardia and Sudden Cardiac Death in Patients with Structural Heart Disease

Heart Rhythm ◽  
2010 ◽  
Vol 7 (11) ◽  
pp. 1720-1721
Author(s):  
Peter Oosterhoff ◽  
Larisa G. Tereshchenko ◽  
Marcel A.G. van der Heyden ◽  
Raja N. Ghanem ◽  
Paul J. De Groot ◽  
...  
Keyword(s):  
Heart Disease ◽  
Ventricular Tachycardia ◽  
Sudden Cardiac Death ◽  
Cardiac Death ◽  
Structural Heart Disease ◽  
Short Term ◽  
Short Term Variability
Sign in / Sign up

Export Citation Format

Share Document