Thromboembolic events and need for anticoagulation therapy following left atrial appendage occlusion in patients with electrical isolation of the appendage

2019 ◽  
Vol 30 (4) ◽  
pp. 511-516 ◽  
Author(s):  
Varuna K. Gadiyaram ◽  
Sanghamitra Mohanty ◽  
Carola Gianni ◽  
Chintan Trivedi ◽  
Amin Al‐Ahmad ◽  
...  
Keyword(s):  
Left Atrial ◽  
Left Atrial Appendage ◽  
Anticoagulation Therapy ◽  
Atrial Appendage ◽  
Thromboembolic Events ◽  
Electrical Isolation ◽  
Left Atrial Appendage Occlusion

scholarly journals ELIMINATION OF THE LEFT ATRIAL APPENDAGE IN THE PREVENTION OF THROMBOEMBOLIC EVENTS IN PATIENTS WITH ATRIAL FIBRILLATION

2019 ◽  
Vol 72 (9) ◽  
pp. 1829-1833
Author(s):  
Urszula Gancarczyk ◽  
Tadeusz Przewłocki ◽  
Piotr Podolec ◽  
Monika Komar
Keyword(s):  
Atrial Fibrillation ◽  
Left Atrial ◽  
Left Atrial Appendage ◽  
Adult Population ◽  
Anticoagulation Therapy ◽  
Atrial Appendage ◽  
Thromboembolic Events ◽  
Left Atrial Appendage Occlusion ◽  
Thromboembolism Events ◽  
Pharmacological Method

Atrial fibrillation (AF) is the most common cardiac arrhythmia in the adult population. Thromboembolic events are one of the reson of increased mortality in this group of patients. Oral anticoagulation therapy significantly reduces the risk of complications, however every tenth patient has contraindications to this treatment. Percutaneous left atrial appendage occlusion (LAAO) is effective, non-pharmacological method of treatment through elimination the source of thromi. This procedure is dedicated to patients with high risk of thromboembolism events and contraindications to anticoagulation.

scholarly journals ACHIEVING LOW RADIATION EXPOSURE AND CONTRAST USAGE WITHOUT COMPROMISING SAFETY AND EFFICACY DURING WATCHMAN LEFT ATRIAL APPENDAGE OCCLUSION DEVICE IMPLANT

2018 ◽  
Vol 7 (3) ◽  
pp. 6-11
Author(s):  
J. А. Reiss ◽  
D. A. Evans
Keyword(s):  
High Risk ◽  
Radiation Exposure ◽  
Left Atrial ◽  
Left Atrial Appendage ◽  
Anticoagulation Therapy ◽  
Atrial Appendage ◽  
Closure Device ◽  
Left Atrial Appendage Occlusion ◽  
Occlusion Device ◽  
Over Time

The study demonstrates the safety, feasibility and effectiveness of a comprehensive approach to minimize fluoroscopy and contrast use during Watchman left atrial closure device implantation.Background. The introduction of Watchman left atrial appendage occlusion device (WM) has provided an effective alternative to anticoagulation for patients with a high risk of cerebrovascular accidents (CVA) and high risk of bleeding and who are unable to take long-term anticoagulation therapy. Since its introduction, WM has been implanted more than 50,000 times worldwide. While the implant procedure is relatively safe, it involves the use of fluoroscopy and contrast and, as such, poses some associated risk to patient safety. The adoption of procedural techniques which reduce fluoroscopy exposure and contrast use have the potential to provide clinical patient benefit without compromising safety or efficacy. Aim To demonstrate that WM implant can be performed with minimal exposure to both ionizing radiation and IV contrast without compromising safety or efficacy.Methods. A retrospective chart review of all 75 consecutive Watchman implantations by a single operator at a single center between December 2015 and December 2017. Every effort to optimize the WM implant procedure and minimize radiation and contrast exposure was incorporated as implant techniques evolved. Contrast and radiation exposure data were collected and analyzed year-over-year.Results. Charts from 75 consecutive cases were reviewed with all cases at index procedure (100%), and included the majority of patients presenting in paroxysmal AF (63%). Baseline patient characteristics were consistent across years. Procedural characteristics also were consistent over time. The median absorbed radiation dose was low (75 mGy in 2015) and did not change significantly over time. Similarly, the median fluoroscopy time used after the initial case was low (2.8 minutes) and did not vary. 73 of 75 (97%) of procedures resulted in successful implantation. There were no procedural complications; notably, no cases resulted in stroke, death, pericardial effusion, vascular accidents or device embolization.Conclusion.The current generation of WM can be successfully implanted using low fluoroscopy and contrast without compromising safety or efficacy using the techniques described.

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