Risk of Sudden Cardiac Death in Chronic Kidney Disease

2013 ◽  
Vol 25 (2) ◽  
pp. 222-231 ◽  
Author(s):  
DIMITRIOS POULIKAKOS ◽  
DEBASISH BANERJEE ◽  
MAREK MALIK
Keyword(s):  
Chronic Kidney Disease ◽  
Sudden Cardiac Death ◽  
Kidney Disease ◽  
Cardiac Death

scholarly journals Haptoglobin Genotype and Risk Markers of Cardiovascular Disease in Patients with Chronic Kidney Disease

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Charlotte Strandhave ◽  
My Svensson ◽  
Henrik Krarup ◽  
Jeppe Hagstrup Christensen
Keyword(s):  
Chronic Kidney Disease ◽  
Sudden Cardiac Death ◽  
Kidney Disease ◽  
Linear Regression ◽  
Regression Model ◽  
Linear Regression Model ◽  
Cardiac Death ◽  
Ckd Stage ◽  
Haptoglobin Genotype ◽  
Hs Crp

Sudden cardiac death and atherosclerosis have a major impact on cardiovascular mortality in chronic kidney disease (CKD). Inflammation with elevated high-sensitive C-reactive protein (hs-CRP) is involved in both sudden cardiac death and atherosclerosis, and decreased heart rate variability (HRV) is a predictor of both sudden cardiac death and atherosclerosis. Haptoglobin (Hp) is characterised by three genotypes (1-1, 2-1, and 2-2) with different antioxidant abilities. The aim was to examine whether HRV and hs-CRP were associated with Hp genotype in CKD patients. Fifty-six patients with CKD stage 2–5 were included. Hp genotype was determined by high-performance liquid chromatography. HRV was analysed from the 24 h Holter recordings. Hs-CRP was measured using an immunoturbidimetric assay. The results show that the HRV indices SDNN and SDANN were significantly lower in the Hp 2-2 patients (P=0.02and 0.04, resp.). In an adjusted linear regression model, Hp 2-2 was associated with both SDNN (P=0.005) and SDANN (P=0.01). Hs-CRP was higher in the Hp 2-2 patients (P=0.002). In an adjusted linear regression model, the association between Hp 2-2 and hs-CRP remained significant (P=0.003). In conclusion, a negative association was observed between Hp 2-2 and HRV, and Hp 2-2 was positively associated with hs-CRP in CKD patients.

scholarly journals Sudden cardiac death in non-dialysis chronic kidney disease patients

2016 ◽  
Vol 36 (4) ◽  
pp. 404-409
Author(s):  
Francisco Caravaca ◽  
Edgar Chávez ◽  
Raúl Alvarado ◽  
Guadalupe García-Pino ◽  
Enrique Luna
Keyword(s):  
Chronic Kidney Disease ◽  
Sudden Cardiac Death ◽  
Kidney Disease ◽  
Cardiac Death

scholarly journals Sympathetic Activation in Hypertensive Chronic Kidney Disease – A Stimulus for Cardiac Arrhythmias and Sudden Cardiac Death?

2020 ◽  
Vol 10 ◽  
Author(s):  
Márcio Galindo Kiuchi ◽  
Jan K. Ho ◽  
Janis Marc Nolde ◽  
Leslie Marisol Lugo Gavidia ◽  
Revathy Carnagarin ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Sudden Cardiac Death ◽  
Kidney Disease ◽  
Cardiac Arrhythmias ◽  
Cardiac Death ◽  
Sympathetic Activation

scholarly journals Prevention of sudden cardiac death in patients with chronic kidney disease

2012 ◽  
Vol 13 (1) ◽  
Author(s):  
Beata Franczyk-Skóra ◽  
Anna Gluba ◽  
Maciej Banach ◽  
Dariusz Kozłowski ◽  
Jolanta Małyszko ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Sudden Cardiac Death ◽  
Kidney Disease ◽  
Cardiac Death
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