Two single nucleotide polymorphisms in the promoter of the ovine myostatin gene (MSTN ) and their effect on growth and carcass muscle traits in New Zealand Romney sheep

2015 ◽  
Vol 133 (3) ◽  
pp. 219-226 ◽  
Author(s):  
J. Wang ◽  
H. Zhou ◽  
J. Hu ◽  
S. Li ◽  
Y. Luo ◽  
...  
Keyword(s):  
New Zealand ◽  
Single Nucleotide Polymorphisms ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Myostatin Gene ◽  
Effect On Growth

scholarly journals Effect of ageing and single nucleotide polymorphisms associated with the risk of aggressive prostate cancer in a New Zealand population

2017 ◽  
Vol 13 (10) ◽  
pp. 1967-1980 ◽  
Author(s):  
Venkatesh Vaidyanathan ◽  
Vijay Naidu ◽  
Nishi Karunasinghe ◽  
Chi Hsiu-Juei Kao ◽  
Radha Pallati ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
New Zealand ◽  
Single Nucleotide Polymorphisms ◽  
Molecular Diagnostics ◽  
Genetic Interactions ◽  
Nucleotide Polymorphisms ◽  
Behavioral Factors ◽  
Single Nucleotide ◽  
Health Concerns ◽  
Male Health

Prostate cancer is one of the most significant male health concerns worldwide. Various researchers carrying out molecular diagnostics have indicated that genetic interactions with biological and behavioral factors play an important role in the overall risk and prognosis of this disease. These will be discussed in details with New Zealand perspective.

Single nucleotide polymorphisms of myostatin gene in Chinese domestic horses

Gene ◽  
2014 ◽  
Vol 538 (1) ◽  
pp. 150-154 ◽  
Author(s):  
Ran Li ◽  
Dong-Hua Liu ◽  
Chun-Na Cao ◽  
Shao-Qiang Wang ◽  
Rui-Hua Dang ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Myostatin Gene ◽  
Domestic Horses

scholarly journals Polymorphic status and phylogenetic analysis of myostatin gene in pak-thoroughbred

Genetika ◽  
2020 ◽  
Vol 52 (3) ◽  
pp. 1281-1290
Author(s):  
Zeshan Raza ◽  
Asif Nadeem ◽  
Maryam Javed ◽  
Faiz-Ul Hassan ◽  
Wasim Shehzad ◽  
...  
Keyword(s):  
Phylogenetic Analysis ◽  
Single Nucleotide Polymorphisms ◽  
Nucleotide Polymorphisms ◽  
Coding Region ◽  
Single Nucleotide ◽  
Exon 2 ◽  
Myostatin Gene ◽  
Thoroughbred Horse ◽  
Mstn Gene ◽  
Thoroughbred Horses

Myostatin is a protein translated by the the MSTN gene (also known as GDF8), is responsible for limiting muscle growth and strength. In thoroughbred horse (Equus Caballus), limited studies have been designed to examine the variants in the coding region of MSTN gene. However, no data is available regarding the single nucleotide polymorphisms (SNPs) of the MSTN about racing performance in thoroughbred horses of Pakistan. In this study blood samples of fifteen Pakistani thoroughbred horses were collected from Race Club Lahore and immediately transferred into the ice box. The DNA was extracted by using phenol-chloroform method. Primers were designed for the amplification of all exons of the MSTN gene. The amplified PCR products were precipitated and sequenced for the identification of SNPs. SNPs were identified by visualizing the peaks of sequenced data by using Chromas Software. Phylogenetic analysis of MSTN gene in Pak-thoroughbred with racing species and some breeds of horses like Marwari Indian breed, Sindhi breed, Kathlawari breed, Italian breed and Chines breed was done separately by using MEGA 6 software. The analysis of identified SNPs were carried out by software SNPator. The sequenced data with altered protein was published in GenBank with accession number MN604194. Results have shown a total of 3 single nucleotide polymorphisms through Blast with reference sequences. Two SNPs were found in exon 2 at position of 2406 (C/T) and 2408 (C/T) respectively. One SNP (T/C) was detected in exon 3 at the position of 4661. In conclusion, Pak-thoroughbred horse population has 3 polymorphisms in their coding region which can be used as a biological marker for athletic abilities in Pak- thoroughbred.

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