Cognitive Behavioural Treatment for Anger in Adults with Intellectual Disabilities: A Systematic Review and Meta-analysis

2012 ◽  
Vol 26 (1) ◽  
pp. 47-62 ◽  
Author(s):  
Matthew Nicoll ◽  
Nigel Beail ◽  
David Saxon
Keyword(s):  
Systematic Review ◽  
Intellectual Disabilities ◽  
Meta Analysis ◽  
Behavioural Treatment ◽  
Cognitive Behavioural Treatment ◽  
Cognitive Behavioural ◽  
Adults With Intellectual Disabilities

scholarly journals The Effectiveness of Cognitive Behavioural Treatment for Non-Specific Low Back Pain: A Systematic Review and Meta-Analysis

PLoS ONE ◽  
2015 ◽  
Vol 10 (8) ◽  
pp. e0134192 ◽  
Author(s):  
Helen Richmond ◽  
Amanda M. Hall ◽  
Bethan Copsey ◽  
Zara Hansen ◽  
Esther Williamson ◽  
...  
Keyword(s):  
Systematic Review ◽  
Low Back Pain ◽  
Back Pain ◽  
Meta Analysis ◽  
Low Back ◽  
Behavioural Treatment ◽  
Cognitive Behavioural Treatment ◽  
Cognitive Behavioural

scholarly journals Association between epilepsy and psychiatric disorders in adults with intellectual disabilities: systematic review and meta-analysis

BJPsych Open ◽  
2021 ◽  
Vol 7 (3) ◽  
Author(s):  
Basma Akrout Brizard ◽  
Bharati Limbu ◽  
Carolina Baeza-Velasco ◽  
Shoumitro Deb
Keyword(s):  
Systematic Review ◽  
Intellectual Disabilities ◽  
Psychiatric Disorders ◽  
Depressive Disorders ◽  
Psychotic Disorders ◽  
Meta Analysis ◽  
Risk Of Bias ◽  
Control Group ◽  
Pool Data ◽  
Adults With Intellectual Disabilities

Background Psychiatric disorders, such as depression and anxiety, are commonly associated with epilepsy in the general population, but the relationship between psychiatric disorders and epilepsy among adults with intellectual disabilities is unclear. Aims To conduct a systematic review and meta-analysis to assess whether epilepsy is associated with an increased rate of psychiatric disorders in adults with intellectual disabilities. Method We included literature published between 1985 and 2020 from four databases, and hand-searched six relevant journals. We assessed risk of bias by using SIGN 50 and the Cochrane risk of bias tool. Several meta-analyses were carried out. Results We included 29 papers involving data on 9594 adults with intellectual disabilities, 3180 of whom had epilepsy and 6414 did not. Of the 11 controlled studies that compared the overall rate of psychiatric disorders between the epilepsy and non-epilepsy groups, seven did not show any significant inter-group difference. Meta-analysis was possible on pooled data from seven controlled studies, which did not show any significant inter-group difference in the overall rate of psychiatric disorders. The rates of psychotic disorders, depressive disorders and anxiety disorders were significantly higher in the non-epilepsy control groups compared with the epilepsy group, with effect sizes of 0.29, 0.47 and 0.58, respectively. Epilepsy-related factors did not show any definite association with psychiatric disorders. Conclusions It is difficult to pool data from such heterogeneous studies and draw any definitive conclusion because most studies lacked an appropriately matched control group, which will be required for future studies.

scholarly journals Association between epilepsy and challenging behaviour in adults with intellectual disabilities: systematic review and meta-analysis

BJPsych Open ◽  
2020 ◽  
Vol 6 (5) ◽  
Author(s):  
Shoumitro Deb ◽  
Basma Akrout Brizard ◽  
Bharati Limbu
Keyword(s):  
Systematic Review ◽  
Intellectual Disabilities ◽  
Large Scale ◽  
Meta Analysis ◽  
Effect Sizes ◽  
Published Data ◽  
Challenging Behaviour ◽  
Intergroup Difference ◽  
Significant Intergroup Difference ◽  
Adults With Intellectual Disabilities

Background Previous systematic reviews showed no significant association between epilepsy and challenging behaviours in adults with intellectual disabilities. Aims To identify whether there is an association between epilepsy and challenging behaviour in adults with intellectual disabilities by carrying out a systematic review of published data. PROSPERO registration number: CRD42020178092. Method We searched five databases and hand-searched six journals. Two authors independently screened titles, abstracts and full articles using a standardised eligibility checklist. Several meta-analyses were carried out. Results The narrative analysis of data from 34 included articles (14 168 adults with intellectual disabilities, 4781 of whom also had epilepsy) showed no significant association between epilepsy and challenging behaviour. Meta-analysis was possible on data from 16 controlled studies. This showed no significant intergroup difference but after sensitivity analysis meta-analysis of 10 studies showed a significantly higher rate of overall challenging behaviour in the epilepsy group (effect size: 0.16) compared with the non-epilepsy group. Aggression and self-injurious behaviour both showed a statistically significant higher rate in the epilepsy group, with very small effect sizes (0.16 and 0.28 respectively). No significant intergroup difference was observed in the rate of stereotypy. Conclusions The findings are contradictory and must be interpreted with caution because of the difficulty in pooling data from varied studies, which is likely to introduce confounding. Where significant differences were found, effect sizes are small and may not be clinically significant, and there are major methodological flaws in the included studies, which should be addressed in future large-scale properly controlled studies.

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