scholarly journals Dose‐dependant acute or subacute disease caused by Burkholderia pseudomallei strain NCTC 13392 in a BALB/c aerosol model of infection

2019 ◽  
Vol 127 (4) ◽  
pp. 1224-1235
Author(s):  
S.G.P. Funnell ◽  
J.A. Tree ◽  
G.J. Hatch ◽  
S.R. Bate ◽  
G. Hall ◽  
...  
Keyword(s):  
Burkholderia Pseudomallei ◽  
Aerosol Model ◽  
Strain Nctc

scholarly journals Sequence Determination of Burkholderia pseudomallei Strain NCTC 13392 Colony Morphology Variants

2013 ◽  
Vol 1 (6) ◽  
Author(s):  
J. Vipond ◽  
J. Kane ◽  
G. Hatch ◽  
J. McCorrison ◽  
W. C. Nierman ◽  
...  
Keyword(s):  
Burkholderia Pseudomallei ◽  
Colony Morphology ◽  
Sequence Determination ◽  
Strain Nctc

ORISAM-TM4: a new global sectional multi-component aerosol model including SOA formation - Focus on carbonaceous BC and OC aerosols

Tellus B ◽  
2007 ◽  
Vol 59 (2) ◽  
Author(s):  
B. Guillaume ◽  
C. Liousse ◽  
R. Rosset ◽  
H. Cachier ◽  
P. Van Velthoven ◽  
...  
Keyword(s):  
Aerosol Model

scholarly journals Novel repurposing of a Laerdal Airway trainer to simulate aerosolisation

2021 ◽  
pp. bmjstel-2020-000802
Author(s):  
Sven Peter Oman ◽  
Scott Helgeson ◽  
Philip Lowman ◽  
Pablo Moreno Franco ◽  
Jonathan Tomshine ◽  
...  
Keyword(s):  
Airway Management ◽  
Ultraviolet Light ◽  
Healthcare Workers ◽  
Saline Solution ◽  
Size Range ◽  
Ambient Air ◽  
Airborne Particles ◽  
Exposure Risk ◽  
Aerosol Model ◽  
The Usa

COVID-19 has claimed over 200 000 lives in the USA and put healthcare workers at risk. Healthcare workers have an increased exposure risk from aerosol-generating procedures such as endotracheal intubation. New barrier designs such as the acrylic box and horizontal plastic drape have emerged to reduce exposure to airborne particles. Particle generating models are needed to test aerosol generating procedure (AGP) barrier designs. To achieve this, an aerosol model that generates a visible and measurable increase in particles which SARS-CoV-2 could travel on and that can also be intubated was created. The model was created using a Laerdal Airway Management Trainer (Laerdal Medical, Stavanger, Norway) combined with a nebuliser and Ambu bag-valve resuscitator (Ambu, Columbia, Maryland, USA). Nebulised Glo Germ (Glo Germ, Moab, Utah, USA) dissolved in saline solution was moved through the tubing and out of the mannequin’s mouth with compression of the Ambu bag. This nebulisation was visualised under ultraviolet light and the quantity of particles between 0.3 and 10.0 μm was measured with a particle counter. Nebulisation was visible exiting the mouth of the mannequin. Nebulised Glo Germ was visualised under ultraviolet light moving in the ambient air. Particles in the size range of 0.3–0.5 µm increased by 20-fold and 1–10 µm increased by 10 252%. SARS-CoV-2 can travel on aerosol and droplet particles and particle generating models are needed to visualise and measure exposure areas and the path particles take during AGPs. We used existing medical and simulation supplies to create a particle simulator.

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