scholarly journals Effects of temperature and medium composition on inhibitory activities of gossypol-related compounds against aflatoxigenic fungi

2013 ◽  
Vol 115 (1) ◽  
pp. 179-186 ◽  
Author(s):  
J.E. Mellon ◽  
M.K. Dowd ◽  
S.B. Beltz
Keyword(s):  
Medium Composition ◽  
Aflatoxigenic Fungi ◽  
Inhibitory Activities ◽  
Effects Of Temperature ◽  
Related Compounds

scholarly journals Phytogrowth-Inhibitory Activities of .BETA.-Dolabrin and .GAMMA.-Thujaplicin, Hinokitiol-Related Compounds and Constituents of Thujopsis dolabrata Sieb. et Zucc. var hondai MAKINO.

2000 ◽  
Vol 23 (5) ◽  
pp. 645-648 ◽  
Author(s):  
Yoshikazu SAKAGAMI ◽  
Yoshihiko INAMORI ◽  
Nami ISOYAMA ◽  
Hiroshi TSUJIBO ◽  
Toshihiro OKABE ◽  
...  
Keyword(s):  
Inhibitory Activities ◽  
Related Compounds

scholarly journals Inhibitory activities and inhibition specificities of caffeic acid derivatives and related compounds toward 5-lipoxygenase.

1989 ◽  
Vol 37 (4) ◽  
pp. 1039-1043 ◽  
Author(s):  
Masanori SUGIURA ◽  
Youichiro NAITO ◽  
Yasunari YAMAURA ◽  
Chikara FUKAYA ◽  
Kazumasa YOKOYAMA
Keyword(s):  
Caffeic Acid ◽  
Caffeic Acid Derivatives ◽  
Inhibitory Activities ◽  
Related Compounds

Growth-inhibitory activities of some 1,4-naphthoquinones and related compounds on Staphylococcus aureus and Escherichia coli

1968 ◽  
Vol 14 (6) ◽  
pp. 661-666 ◽  
Author(s):  
G. J. Leahy ◽  
D. J Currie ◽  
H. L. Holmes ◽  
J. R. Maltman
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Electron Transport ◽  
Electron Transport Chain ◽  
Growth Inhibitory ◽  
Transport Chain ◽  
Half Wave ◽  
Inhibitory Activities ◽  
Related Compounds

Growth-inhibitory activities of some or all of 98 1,4-naphthoquinones and 16 related compounds on Escherichia coli and two strains of Staphylococcus aureus were determined alone or in combination. These values, when plotted against their polarographic half-wave potentials and those of their C2-n-butylthio analogs support the hypothesis that these compounds, or the products resulting from their reaction with a protein nucleophile, function by short-circuiting one or other of the quinones present in the electron-transport chain.

scholarly journals New inhibitors of methane production by rumen micro-organisms. Development and testing of inhibitors in vitro

1975 ◽  
Vol 34 (3) ◽  
pp. 429-446 ◽  
Author(s):  
J. W. Czerkawski ◽  
Grace Breckenridge
Keyword(s):  
Methane Production ◽  
Trichloroacetic Acid ◽  
Physical State ◽  
Pivalic Acid ◽  
Relative Activity ◽  
State Density ◽  
Inhibitory Activities ◽  
Micro Organisms ◽  
Related Compounds

1. A procedure is described for assaying in vitro the activity of various inhibitors of methane production by rumen micro-organisms.2. Methods of preparation of various inhibitors are described together with attempts to characterize these compounds by determining their physical properties (physical state, density, chromatographic behaviour), their hydrolysis by rumen contents and their relative potency as inhibitors.3. The results of preliminary studies with trichloroethanol and its ester with pivalic acid are given.4. The inhibitory activities of several groups of related compounds are reported. These include the polyhalogenated alcohols and their esters with pivalic acid, the esters of trihalogenated alcohols and monobasic fatty acids from C2to C16and the trihalogenated alcohol esters of dibasic acids. The results of experiments with esters of alcohols and polyhalogenated carboxylic and sulphonic acids are also given.5. It is concluded that the mechanism of action of the inhibitors might be similar to that of known polyhalogenated methane analogues (e.g. chloroform). The relative activity of various compounds might be partly governed by the ease of their absorption into the microbial cells and by the extent to which the esters can be hydrolysed by rumen contents.6. The results show that some substances are very poor inhibitors, unless they are esterified (e.g. trichloroacetic acid) but on the whole the esters in which the polyhalogen grouping is on the alcohol portion of the molecule are better inhibitors than those in which it is on the acid portion of the molecule.

The inhibitory activities of 480156-S and its related compounds on prostaglandin synthetase.

1987 ◽  
Vol 90 (5) ◽  
pp. 295-302 ◽  
Author(s):  
Toshiro YAMAGUCHI ◽  
Katsumi HIROSE ◽  
Yutaka NAKAMURA ◽  
Koichi SUGENO
Keyword(s):  
Prostaglandin Synthetase ◽  
Inhibitory Activities ◽  
Related Compounds

scholarly journals Effects of Temperature, Salinity, and Medium Composition on Compatible Solute Accumulation byThermococcus spp

1998 ◽  
Vol 64 (10) ◽  
pp. 3591-3598 ◽  
Author(s):  
Pedro Lamosa ◽  
Lígia O. Martins ◽  
Milton S. Da Costa ◽  
Helena Santos
Keyword(s):  
Compatible Solutes ◽  
Medium Composition ◽  
Compatible Solute ◽  
Resonance Spectroscopy ◽  
Thermococcus Litoralis ◽  
Solute Accumulation ◽  
Organic Solute ◽  
Low Levels ◽  
Effects Of Temperature ◽  
Thermococcus Celer

ABSTRACT The effects of salinity and growth temperature on the accumulation of intracellular organic solutes were examined by nuclear magnetic resonance spectroscopy (NMR) in Thermococcus litoralis,Thermococcus celer, Thermococcus stetteri, andThermococcus zilligii (strain AN1). In addition, the effects of growth stage and composition of the medium were studied inT. litoralis. A novel compound identified as β-galactopyranosyl-5-hydroxylysine was detected in T. litoralis grown on peptone-containing medium. Besides this newly discovered compound, T. litoralis accumulated mannosylglycerate, aspartate, α-glutamate, di-myo-inositol-1,1′(3,3′)-phosphate, hydroxyproline, and trehalose. The hydroxyproline and β-galactopyranosyl-5-hydroxylysine were probably derived from peptone, while the trehalose was derived from yeast extract; none of these three compounds was detected in the other Thermococcus strains examined. Di-myo-inositol-1,1′(3,3′)-phosphate, aspartate, and mannosylglycerate were detected in T. celer and T. stetteri, and the latter organism also accumulated α-glutamate. The only nonmarine species studied, T. zilligii, accumulated very low levels of α-glutamate and aspartate. The levels of mannosylglycerate and aspartate increased in T. litoralis, T. celer, and T. stetteri in response to salt stress, while di-myo-inositol-1,1′(3,3′)-phosphate was the major intracellular solute at supraoptimal growth temperatures. The phase of growth had a strong influence on the types and levels of compatible solutes in T. litoralis; mannosylglycerate and aspartate were the major solutes during exponential growth, while di-myo-inositol-1,1′(3,3′)-phosphate was the predominant organic solute during the stationary phase of growth. This work revealed an unexpected ability of T. litoralis to scavenge suitable components from the medium and to use them as compatible solutes.

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