scholarly journals Silver colloidal nanoparticles: effect on matrix composition and structure of Candida albicans and Candida glabrata biofilms

2013 ◽  
Vol 114 (4) ◽  
pp. 1175-1183 ◽  
Author(s):  
D.R. Monteiro ◽  
S. Silva ◽  
M. Negri ◽  
L.F. Gorup ◽  
E.R. de Camargo ◽  
...  
Keyword(s):  
Candida Albicans ◽  
Candida Glabrata ◽  
Matrix Composition ◽  
Colloidal Nanoparticles ◽  
Composition And Structure ◽  
Silver Colloidal Nanoparticles

scholarly journals Environmental pH modulates biofilm formation and matrix composition in Candida albicans and Candida glabrata

Biofouling ◽  
2020 ◽  
Vol 36 (5) ◽  
pp. 621-630
Author(s):  
Bruna Gonçalves ◽  
Liliana Fernandes ◽  
Mariana Henriques ◽  
Sónia Silva
Keyword(s):  
Candida Albicans ◽  
Biofilm Formation ◽  
Candida Glabrata ◽  
Matrix Composition

FORMACIÓN DE BIOPELÍCULAS Y SENSIBILIDAD A ANTIFÚNGICOS DE Candida albicans, Candida tropicalis Y Candida glabrata

2021 ◽  
pp. 93-105
Author(s):  
Alejandra Paula Espinosa Texis ◽  
Débora Vázquez Domínguez ◽  
David Iván Loaiza Toscuento ◽  
Teresita Spezzia Mazzocco
Keyword(s):  
Candida Albicans ◽  
Candida Tropicalis ◽  
Candida Glabrata

scholarly journals Antifungal Activity of a Hydroethanolic Extract From Astronium urundeuva Leaves Against Candida albicans and Candida glabrata

2019 ◽  
Vol 10 ◽  
Author(s):  
Bruna Vidal Bonifácio ◽  
Taissa Vieira Machado Vila ◽  
Isadora Fantacini Masiero ◽  
Patrícia Bento da Silva ◽  
Isabel Cristiane da Silva ◽  
...  
Keyword(s):  
Candida Albicans ◽  
Antifungal Activity ◽  
Candida Glabrata ◽  
Hydroethanolic Extract

Hormones modulate Candida vaginal isolates biofilm formation and decrease their susceptibility to azoles and hydrogen peroxide

2019 ◽  
Vol 58 (3) ◽  
pp. 341-350
Author(s):  
Bruna Gonçalves ◽  
Nuno Miguel Azevedo ◽  
Mariana Henriques ◽  
Sónia Silva
Keyword(s):  
Hydrogen Peroxide ◽  
Candida Albicans ◽  
Biofilm Formation ◽  
Candida Glabrata ◽  
The Other ◽  
Environmental Cues ◽  
Intrauterine Devices ◽  
Normal Cycle ◽  
Acidic Conditions ◽  
High Adaptation

Abstract Vulvovaginal candidiasis (VVC) is an infection usually caused by Candida albicans and increasingly by Candida glabrata, which has an intrinsically high resistance to commonly used antifungals. Candida species possess virulence factors that contribute to VVC development, as the ability to form biofilms in vaginal walls and intrauterine devices. It is known that VVC is promoted by conditions that increase the hormones levels, during pregnancy, however, the effects of hormones on Candida cells are poorly studied, especially in C. glabrata. Thus, the influence of progesterone and β-estradiol, at normal cycle and pregnancy concentrations, on biofilm formation and resistance of C. albicans and C. glabrata vaginal isolates, was analyzed using acidic conditions (pH 4). Biofilms of C. albicans developed in the presence of hormones presented reduced biomass (up to 65%) and impaired cells ability to produce filamentous forms. On the other hand, C. glabrata presented high adaptation to the presence of hormones, which did not affect its biofilm formation. Additionally, hormones impaired the susceptibility of C. albicans and C. glabrata cells to azoles, with potential clinical significance in the presence of pregnancy hormone levels. A similar result was obtained for the susceptibility to hydrogen peroxide, a biological vaginal barrier against Candida growth. Overall, the results of this study suggest that hormones may act as environmental cues promoting Candida protection from vaginal defenses and harmful conditions, what may have implications in Candida vaginal pathogenicity and treatment of VVC, especially in C. glabrata infections due to its high adaptability to vaginal conditions.

scholarly journals The The Effects of Cinnamaldehyde (Cinnamon Derivatives) and Nystatin on Candida Albicans and Candida Glabrata

2019 ◽  
Vol 7 (7) ◽  
pp. 1067-1070 ◽  
Author(s):  
Sedigheh Bakhtiari ◽  
Soudeh Jafari ◽  
Jamileh Bigom Taheri ◽  
Tahereh Sadat Jafarzadeh Kashi ◽  
Zahra Namazi ◽  
...  
Keyword(s):  
Candida Albicans ◽  
Minimum Inhibitory Concentration ◽  
Candida Species ◽  
Candida Glabrata ◽  
Inhibitory Concentration ◽  
Fungal Infections ◽  
Fungal Growth ◽  
Minimum Fungicidal Concentration ◽  
Microdilution Method

BACKGROUND: Candida species are the most common opportunistic fungal infections. Today, cinnamon plants have been considered for anti-Candida properties. AIM: This study aimed to investigate the effectiveness of cinnamaldehyde extract (from cinnamon derivatives) on Candida albicans and Candida glabrata species and comparison with nystatin. MATERIAL AND METHODS: In this study, cinnamaldehyde and nystatin were used. The specimens included Candida albicans and Candida glabrata. Minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) were measured for each one by the microdilution method. This experiment was repeated three times. RESULTS: Cinnamaldehyde extract at a concentration of 62.5 μl/ml was able to prevent the growth of Candida albicans, at a concentration of 93.7 μl/ml, causing Candida albicans to disappear, at 48.8 μl/ml, to prevent the growth of Candida glabrata, and in the concentration of 62.5 μl/ml, causes the loss of Candida glabrata. In comparison, nystatin at 0.5 μg/ml concentration prevented the growth of Candida albicans, at concentrations of 1 μg/ml causing Candida albicans to be destroyed, at 4 μg/ml concentration to prevent the growth of Candida glabrata, and at a concentration of 8 μg/ml causes the loss of Candida glabrata. The results were the same every three times. CONCLUSIONS: Although cinnamaldehyde extract had an effect on fungal growth in both Candida albicans and Candida glabrata with a fatal effect; the effect on these two species was lower than nystatin.

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