scholarly journals A bioreactor for studying negative pressure wound therapy on skin grafts

2021 ◽  
Author(s):  
Gabrielle Notorgiacomo ◽  
Justin Klug ◽  
Scott Rapp ◽  
Steven T. Boyce ◽  
Stacey C. Schutte
Keyword(s):  
Negative Pressure ◽  
Negative Pressure Wound Therapy ◽  
Skin Grafts ◽  
Wound Therapy

scholarly journals Full circumference lower extremity degloving injury treated with hydrosurgical debridement and negative-pressure wound therapy with gauze wound filler for fixation of avulsed flap skin grafts

2020 ◽  
Vol 2020 (12) ◽  
Author(s):  
Tae Nagama ◽  
Natsuko Kakudo ◽  
Atsuyuki Kuro ◽  
Yujiro Ozaki ◽  
Yasuko Shirasawa ◽  
...  
Keyword(s):  
Lower Extremity ◽  
Negative Pressure ◽  
Negative Pressure Wound Therapy ◽  
Traumatic Injury ◽  
Skin Grafts ◽  
Wound Therapy ◽  
Left Lower Extremity ◽  
Degloving Injury ◽  
Severe Traumatic Injury ◽  
Degloving Injuries

Abstract Degloving, a skin and subcutis avulsion, is a severe traumatic injury sometimes caused by rolling wheels or machines. Although avulsed flaps are often readapted to its original site, most of these tissues become necrotic. Due to the extensive skin and soft tissue deficiency caused by necrosis, treatment becomes difficult. Skin grafts harvested from avulsed flaps may be used to treat degloving injuries, while negative pressure wound therapy (NPWT) is used to secure the grafts. Commonly used porous polyurethane foam wound fillers are difficult to set in circumferential extremity degloving injuries; gauze-based wound fillers are easier to use and cause less pain during dressing changes. We present a case of an extensive, full-circumference left lower-extremity degloving injury, treated using NPWT with gauze-based wound fillers for fixation of skin grafts harvested from avulsed flaps after hydrosurgical debridement. For complex wound geometries, gauze-based wound fillers can be easily applied for skin graft immobilization.

Negative pressure wound therapy using polyvinyl alcohol foam to bolster full-thickness mesh skin grafts in dogs

2017 ◽  
Vol 46 (3) ◽  
pp. 389-395 ◽  
Author(s):  
Matan Or ◽  
Bart Van Goethem ◽  
Adriaan Kitshoff ◽  
Annika Koenraadt ◽  
Ilona Schwarzkopf ◽  
...  
Keyword(s):  
Polyvinyl Alcohol ◽  
Negative Pressure ◽  
Negative Pressure Wound Therapy ◽  
Skin Grafts ◽  
Full Thickness ◽  
Wound Therapy

scholarly journals An Alternative Treatment Strategy for Complicated Chronic Wounds: Negative Pressure Therapy over Mesh Skin Graft

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Michele Maruccia ◽  
Maria G. Onesti ◽  
Valentina Sorvillo ◽  
Antonio Albano ◽  
Luca A. Dessy ◽  
...  
Keyword(s):  
Skin Graft ◽  
Negative Pressure ◽  
Negative Pressure Wound Therapy ◽  
Tissue Growth ◽  
Real Problem ◽  
Skin Defect ◽  
Skin Grafts ◽  
Wound Therapy ◽  
Pressure Therapy ◽  
Mesh Skin Graft

Extensive skin defect represents a real problem and major challenge in plastic and reconstructive surgery. On one hand, skin grafts offer a practical method to deal with skin defects despite their unsuitability for several complicated wounds. On the other hand, negative pressure wound therapy (NPWT), applied before skin grafting, promotes granulation tissue growth. The aim of the study is to evaluate the improvement in wound healing given by the merger of these two different approaches. We treated 23 patients for large wounds of multiple factors. Of these, 15 were treated with the application of V.A.C.® Therapy (KCI Medical S.r.l., Milan, Italy), in combination with skin grafts after a prior unsuccessful treatment of 4 weeks with mesh skin grafts and dressings. Another 8 were treated with only mesh skin graft. Pain reduction and wound area reduction were found statistically significant (p<0.0009,p<0.0001). Infection was resolved in almost all patients. According to our study, the use of the negative pressure wound therapy over mesh skin grafts is significantly effective especially in wounds resistant to conventional therapies, thereby improving the rate of skin graft take.

A retrospective analysis of securing autologous split-thickness skin grafts with negative pressure wound therapy in paediatric burn patients

Burns ◽  
2014 ◽  
Vol 40 (6) ◽  
pp. 1116-1120 ◽  
Author(s):  
Michael Hoeller ◽  
Michael Valentin Schintler ◽  
Klaus Pfurtscheller ◽  
Lars-Peter Kamolz ◽  
Norbert Tripolt ◽  
...  
Keyword(s):  
Retrospective Analysis ◽  
Negative Pressure ◽  
Negative Pressure Wound Therapy ◽  
Burn Patients ◽  
Skin Grafts ◽  
Wound Therapy ◽  
Thickness Skin

scholarly journals Effects of Negative Pressure Wound Therapy on Healing of Free Full-Thickness Skin Grafts in Dogs

2013 ◽  
Vol 42 (5) ◽  
pp. 511-522 ◽  
Author(s):  
Bryden J. Stanley ◽  
Kathryn A. Pitt ◽  
Christian D. Weder ◽  
Michele C. Fritz ◽  
Joe G. Hauptman ◽  
...  
Keyword(s):  
Negative Pressure ◽  
Negative Pressure Wound Therapy ◽  
Skin Grafts ◽  
Full Thickness ◽  
Wound Therapy ◽  
Full Thickness Skin ◽  
Thickness Skin

scholarly journals Management of large chronic venous leg ulcers with negative pressure wound therapy

2017 ◽  
Vol 4 (2) ◽  
pp. 17
Author(s):  
Dominik Andrzej Walczak ◽  
Michał Wojtyniak ◽  
Rajmund Jaguścik ◽  
Joanna Jadwiga Porzeżyńska ◽  
Wojciech Fałek ◽  
...  
Keyword(s):  
Negative Pressure ◽  
Negative Pressure Wound Therapy ◽  
Adult Population ◽  
Complete Healing ◽  
Leg Ulcers ◽  
Skin Grafts ◽  
Wound Therapy ◽  
Venous Leg Ulcers ◽  
Venous Ulcers ◽  
The Mean

Introduction: Venous leg ulcers (VLU) occur in 1\% of the adult population and are associated with chronic disability, diminished quality of life and high health-care costs. Treatment is often slow, difficult and recurrence is high because of inappropriate conditions of the wound bed. Patients and Methods: This study involves 14 patients with chronic venous ulcers larger than 100 cm\textsuperscript{2} treated with negative pressure wound therapy (NPWT). Patients underwent a radical debridement of all devitalized tissues and partial stripping of an insufficient great saphenous vein in the first operation. After adequate haemostasis, NPWT kit was applied. Once the wounds were determined to be clean and adequate granulation tissue formation was achieved, split-thickness skin grafts were applied. Dressing impregnated with neutral triglycerides and silver ions was used as a first layer and the black polyurethane NPWT foam was applied over it. The pain assessment was performed for 7 patients using 10 cm visual analog scale (VAS). Results: The mean number of NPWT dressing changes prior to grafting was 5.8. The mean number of NPWT foam changes was 2.8 after skin grafting. We accomplished complete healing of 92\% of applied skin grafts surface. One patient had recurrence of venous ulcers in the follow-up period. Moreover, one patient required regrafting. Conclusions: The application of NPWT provides quick wound-bed preparation and high graft take in venous ulcer treatment.

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