scholarly journals Seasonality and clinical impact of human parainfluenza viruses

2018 ◽  
Vol 12 (6) ◽  
pp. 706-716 ◽  
Author(s):  
Philip Maykowski ◽  
Marie Smithgall ◽  
Philip Zachariah ◽  
Matthew Oberhardt ◽  
Celibell Vargas ◽  
...  
Keyword(s):  
Clinical Impact ◽  
Parainfluenza Viruses ◽  
Human Parainfluenza Viruses

scholarly journals Distribution and Trends of Human Parainfluenza Viruses in Hospitalised Children

2016 ◽  
Vol 83 (10) ◽  
pp. 1109-1113 ◽  
Author(s):  
M. Anjaneya Swamy ◽  
Bharti Malhotra ◽  
P. V. Janardhan Reddy ◽  
Neeraj Kumar ◽  
Jitendra Kumar Tiwari ◽  
...  
Keyword(s):  
Parainfluenza Viruses ◽  
Human Parainfluenza Viruses

The landscape of extrapulmonary manifestations of human parainfluenza viruses: A systematic narrative review

2020 ◽  
Author(s):  
Mohammad Farahmand ◽  
Somayeh Shatizadeh Malekshahi ◽  
Mohammad Reza Jabbari ◽  
Mohammad Shayestehpour
Keyword(s):  
Narrative Review ◽  
Parainfluenza Viruses ◽  
Human Parainfluenza Viruses

scholarly journals Parainfluenza Viruses

2003 ◽  
Vol 16 (2) ◽  
pp. 242-264 ◽  
Author(s):  
Kelly J. Henrickson
Keyword(s):  
Respiratory Infections ◽  
Chronically Ill ◽  
The Elderly ◽  
Structure And Function ◽  
Medium Size ◽  
Parainfluenza Viruses ◽  
And Function ◽  
Negative Sense ◽  
Human Parainfluenza Viruses ◽  
Molecular Structure And Function

SUMMARY Human parainfluenza viruses (HPIV) were first discovered in the late 1950s. Over the last decade, considerable knowledge about their molecular structure and function has been accumulated. This has led to significant changes in both the nomenclature and taxonomic relationships of these viruses. HPIV is genetically and antigenically divided into types 1 to 4. Further major subtypes of HPIV-4 (A and B) and subgroups/genotypes of HPIV-1 and HPIV-3 have been described. HPIV-1 to HPIV-3 are major causes of lower respiratory infections in infants, young children, the immunocompromised, the chronically ill, and the elderly. Each subtype can cause somewhat unique clinical diseases in different hosts. HPIV are enveloped and of medium size (150 to 250 nm), and their RNA genome is in the negative sense. These viruses belong to the Paramyxoviridae family, one of the largest and most rapidly growing groups of viruses causing significant human and veterinary disease. HPIV are closely related to recently discovered megamyxoviruses (Hendra and Nipah viruses) and metapneumovirus.

scholarly journals Simultaneous Detection and Identification of Human Parainfluenza Viruses 1, 2, and 3 from Clinical Samples by Multiplex PCR

1998 ◽  
Vol 36 (5) ◽  
pp. 1388-1391 ◽  
Author(s):  
Juan E. Echevarría ◽  
Dean D. Erdman ◽  
Ella M. Swierkosz ◽  
Brian P. Holloway ◽  
Larry J. Anderson
Keyword(s):  
Simultaneous Detection ◽  
Clinical Samples ◽  
Rt Pcr ◽  
Negative Results ◽  
Parainfluenza Viruses ◽  
Detection And Identification ◽  
Serotype 1 ◽  
Pcr Assays ◽  
Syncytial Virus ◽  
Human Parainfluenza Viruses

Reverse transcription (RT)-PCR assays have been widely described for use in the diagnosis of human parainfluenza viruses (HPIVs) and other respiratory virus pathogens. However, these assays are mostly monospecific, requiring separate amplifications for each HPIV type. In the present work, we describe multiplex RT-PCR assays that detect and differentiate HPIV serotypes 1, 2, and 3 in a combined reaction. Specifically, a mixture of three pairs of primers to conserved regions of the hemagglutinin-neuraminidase gene of each HPIV serotype was used for primary amplification, yielding amplicons with similar sizes. For typing, a second amplification was performed with a mixture of nested primers, yielding amplicons with sizes easily differentiated by agarose gel electrophoresis. A modified single-amplification RT-PCR assay with fluorescence-labeled nested primers, followed by analysis of the labeled products on an automated sequencing gel, was also evaluated. Fifteen temporally and geographically diverse HPIV isolates from the Centers for Disease Control and Prevention archives and 26 of 30 (87%) previously positive nasopharyngeal specimens (8 of 10 positive for HPIV serotype 1 [HPIV1], 9 of 10 positive for HPIV2, and 9 of 10 positive for HPIV3) were positive and were correctly typed by both assays. Negative results were obtained with naso- or oropharyngeal specimens and/or culture isolates of 33 unrelated respiratory tract pathogens, including HPIV4, enterovirus, rhinovirus, respiratory syncytial virus, adenovirus, influenza virus, and Streptococcus pneumoniae. Our multiplex RT-PCR assays provide sensitive, specific, and simplified tools for the rapid diagnosis of HPIV infections.

scholarly journals Survival of human parainfluenza viruses in the South Polar environment.

1983 ◽  
Vol 46 (4) ◽  
pp. 901-905 ◽  
Author(s):  
A J Parkinson ◽  
H G Muchmore ◽  
E N Scott ◽  
L V Scott
Keyword(s):  
The South ◽  
Parainfluenza Viruses ◽  
Polar Environment ◽  
Human Parainfluenza Viruses ◽  
South Polar

Upper respiratory tract infections, including influenza

2018 ◽  
Author(s):  
Pippa Newton
Keyword(s):  
Natural History ◽  
Respiratory Tract ◽  
Respiratory Tract Infections ◽  
Upper Respiratory Tract Infections ◽  
Upper Respiratory Tract ◽  
Type B ◽  
Parainfluenza Viruses ◽  
Upper Respiratory ◽  
Tract Infections ◽  
Human Parainfluenza Viruses

Infections of the nasal cavity, sinuses, pharynx, epiglottis, and larynx are termed upper respiratory tracts infections. These include acute coryza, pertussis, sinusitis, pharyngitis, tonsillitis, epiglottitis, laryngitis, laryngotracheobronchitis, and influenza. Rhinoviruses and coronaviruses account for the majority of acute coryzal illnesses. Acute sinusitis (<4 weeks duration) is also usually viral in origin. About 70% of pharyngitis and tonsillitis cases are viral in etiology. Haemophilus influenzae (Type B) is responsible for most cases of epiglottitis. Acute laryngitis and laryngotracheobronchitis are usually caused by human parainfluenza viruses. This chapter focuses on upper respiratory tract infections, including their etiology, symptoms, demographics, natural history, complications, diagnosis, prognosis, and treatment.

Structural and antigenic properties of human parainfluenza viruses

1985 ◽  
Vol 3 ◽  
pp. 78
Author(s):  
R.D. Barry ◽  
J.A. Cowley ◽  
O.T. Chisholm ◽  
S.G. Richards
Keyword(s):  
Parainfluenza Viruses ◽  
Antigenic Properties ◽  
Human Parainfluenza Viruses
Sign in / Sign up

Export Citation Format

Share Document