scholarly journals Infants born full term and preterm increase the height of anti‐gravity leg movements during a kick‐activated mobile task using a scaffolded task environment

Infancy ◽  
2020 ◽  
Vol 26 (1) ◽  
pp. 168-183
Author(s):  
Jeong Ah Kim ◽  
Linda Fetters ◽  
Masayoshi Kubo ◽  
Sandrah P. Eckel ◽  
Barbara Sargent
2020 ◽  
Vol 100 (12) ◽  
pp. 2217-2226
Author(s):  
Barbara Sargent ◽  
Kathryn L Havens ◽  
Jessica L Wisnowski ◽  
Tai-Wei Wu ◽  
Masayoshi Kubo ◽  
...  

Abstract Objective Children with spastic cerebral palsy (CP) have gait impairments resulting from decreased selective motor control, an inability to move the leg joints independently of one another, relying on excessive flexion or extension coupling across the 3 joints. Infants with white matter injury are at high risk of CP and have decreased selective motor control as early as 1 month corrected age. An in-home kicking-activated mobile task was developed to motivate more selective hip-knee control of infants at high risk of CP. The purposes of this study were to determine the feasibility of the in-home mobile task and to determine whether infants at high risk of CP and infants with typical development (TD) learn the association between their leg movements and mobile activation. Methods Ten infants at high risk of CP based on neuroimaging and 11 infants with TD participated in this cohort study at 3.5 to 4.5 months corrected age. Each infant participated in the in-home kicking-activated mobile task for 8 to 10 min/d, 5 d/wk, for 6 weeks. Learning was assessed weekly based on an increase in the time that the infant demonstrated the reinforced leg actions when interacting with the kicking-activated mobile compared with spontaneous kicking. Results With regard to feasibility, participation averaged 92% for infants at high risk of CP and 99% for infants with TD. With regard to learning, the group at high risk of CP demonstrated learning of the task for 2 of 6 weeks, whereas the group with TD demonstrated learning for all 6 weeks. Conclusions Infants at high risk of CP demonstrated learning of the kicking-activated mobile task but at a reduced amount compared with infants with TD. Further research is necessary to determine whether the kicking-activated mobile task has potential as an intervention to motivate more selective hip-knee control and improve walking outcomes of infants at high risk of CP. Impact This study investigated the feasibility of an in-home kicking-activated mobile task, a discovery learning task designed to motivate infants at high risk of CP to engage in the intensive task practice necessary to promote their learning abilities and selective motor control. Lay Summary CP is a lifelong disorder of movement caused by abnormal development or early damage to the brain. If an in-home infant kicking-activated mobile task could be used to motivate certain types of age-appropriate leg movements of infants who are at high risk of CP, the task could help improve walking outcomes, which eventually could contribute to improving children’s ability to participate in daily life. This study showed that infants at high risk of CP did learn the infant kicking-activated mobile task but at a much reduced amount compared with infants who are developing typically; so, this is a first step in determining whether the task has potential to motivate more age-appropriate leg movements in infants at high risk of cerebral palsy.


1996 ◽  
Vol 29 (4) ◽  
pp. 335-351 ◽  
Author(s):  
Julia J. Geerdink ◽  
Brian Hopkins ◽  
Wiero J. Beek ◽  
Carolyn B. Heriza
Keyword(s):  

2012 ◽  
Author(s):  
R. Montirosso ◽  
S. Moriconi ◽  
B. Riccardi ◽  
G. Reni ◽  
F. Arrigoni ◽  
...  

2002 ◽  
Author(s):  
Wayne C. Harris ◽  
Raja Parasuraman ◽  
Marla Zinni ◽  
Peter A. Hancock ◽  
Scot C. Harris
Keyword(s):  

1978 ◽  
Vol 39 (03) ◽  
pp. 751-758 ◽  
Author(s):  
B L Sheppard ◽  
J Bonnar

SummaryThe fibrinolytic activity of the intimal cells of decidual spiral arteries and the syncytium of placental villi was studied by electron microscopy in ten normal full-term human pregnancies using a modification of the fibrin slide technique. Endothelial cells lining the intima of the decidual spiral arteries showed a considerably greater fibrinolytic activity than intimal cytotrophoblast and the syncytiotrophoblast showed no activity.The replacement of endothelial cells by an intimal lining of cytotrophoblast, and the presence of cytotrophoblast in the media, appears to play an important role in the reduction of the fibrinolytic activity of the vessel. This inhibition of fibrinolytic activity in the utero-placental arteries may be the physiological mechanism which controls fibrin deposition in these vessels and on the placental villi.


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