scholarly journals Memory CD8 + T cells exhibit tissue imprinting and non‐stable exposure‐dependent reactivation characteristics following blood‐stage Plasmodium berghei ANKA infections

Immunology ◽  
2021 ◽  
Author(s):  
Tovah N. Shaw ◽  
Michael J. Haley ◽  
Rebecca S. Dookie ◽  
Jenna J. Godfrey ◽  
Antonn J. Cheeseman ◽  
...  
Keyword(s):  
T Cells ◽  
Cd8 T Cells ◽  
Plasmodium Berghei ◽  
Blood Stage ◽  
Plasmodium Berghei Anka ◽  
Memory Cd8 T Cells

scholarly journals Efficient Development ofPlasmodiumLiver Stage–Specific Memory CD8+T Cells during the Course of Blood‐Stage Malarial Infection

2007 ◽  
Vol 196 (12) ◽  
pp. 1827-1835 ◽  
Author(s):  
Julius C. R. Hafalla ◽  
Urvashi Rai ◽  
Dabeiba Bernal‐Rubio ◽  
Ana Rodriguez ◽  
Fidel Zavala
Keyword(s):  
T Cells ◽  
Cd8 T Cells ◽  
Blood Stage ◽  
Memory Cd8 T Cells ◽  
Malarial Infection ◽  
Specific Memory

scholarly journals Development of Memory CD8+T Cells and Their Recall Responses during Blood-Stage Infection withPlasmodium bergheiANKA

2012 ◽  
Vol 189 (9) ◽  
pp. 4396-4404 ◽  
Author(s):  
Mana Miyakoda ◽  
Daisuke Kimura ◽  
Kiri Honma ◽  
Kazumi Kimura ◽  
Masao Yuda ◽  
...  
Keyword(s):  
T Cells ◽  
Cd8 T Cells ◽  
Blood Stage ◽  
Memory Cd8 T Cells ◽  
Blood Stage Infection ◽  
Stage Infection

scholarly journals Inducible Costimulator Expressing T Cells Promote Parasitic Growth During Blood Stage Plasmodium berghei ANKA Infection

2018 ◽  
Vol 9 ◽  
Author(s):  
Gajendra M. Jogdand ◽  
Soumya Sengupta ◽  
Gargee Bhattacharya ◽  
Santosh Kumar Singh ◽  
Prakash Kumar Barik ◽  
...  
Keyword(s):  
T Cells ◽  
Plasmodium Berghei ◽  
Blood Stage ◽  
Plasmodium Berghei Anka ◽  
Inducible Costimulator

scholarly journals Comparative Study of Brain CD8+ T Cells Induced by Sporozoites and Those Induced by Blood-Stage Plasmodium berghei ANKA Involved in the Development of Cerebral Malaria

2004 ◽  
Vol 72 (5) ◽  
pp. 2817-2826 ◽  
Author(s):  
Sébastien Bagot ◽  
Fatima Nogueira ◽  
Alexis Collette ◽  
Virgilio do Rosario ◽  
François Lemonier ◽  
...  
Keyword(s):  
T Cells ◽  
Cerebral Malaria ◽  
Cd8 T Cells ◽  
Plasmodium Berghei ◽  
Blood Stage ◽  
Necrosis Factor Alpha ◽  
Histocompatibility Complex ◽  
Blood Stage Infection ◽  
Factor Alpha ◽  
Necrosis Factor

ABSTRACT To obtain insight into the mechanisms that contribute to the pathogenesis of Plasmodium infections, we developed an improved rodent model that mimics human malaria closely by inducing cerebral malaria (CM) through sporozoite infection. We used this model to carry out a detailed study on isolated T cells recruited from the brains of mice during the development of CM. We compared several aspects of the immune response related to the experimental model of Plasmodium berghei ANKA infection induced by sporozoites in C57BL/6 mice and those related to a blood-stage infection. Our data show that in both models, oligoclonal TCRVβ4+, TCRVβ6+, TCRVβ8.1+, and TCRVβ11+ major histocompatibility complex class I-restricted CD8 T cells were present in the brains of CM+ mice. These CD8+ T cells display an activated phenotype, do not undergo apoptosis, secrete gamma interferon or tumor necrosis factor alpha, and are associated with the development of the neurological syndrome.

Antigen cross-presentation in the liver generates protective memory CD8+ T cells in the absence of inflammation

2012 ◽  
Vol 50 (01) ◽  
Author(s):  
JP Böttcher ◽  
D Stabenow ◽  
S Debey-Pascher ◽  
A Staratschek-Jox ◽  
J Grell ◽  
...  
Keyword(s):  
T Cells ◽  
Cd8 T Cells ◽  
Memory Cd8 T Cells ◽  
Cross Presentation
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