scholarly journals Reversible lacrimal gland-protective regulatory T-cell dysfunction underlies male-specific autoimmune dacryoadenitis in the non-obese diabetic mouse model of Sjögren syndrome

Immunology ◽  
2015 ◽  
Vol 145 (2) ◽  
pp. 232-241 ◽  
Author(s):  
Scott M. Lieberman ◽  
Portia A. Kreiger ◽  
Gary A. Koretzky
Keyword(s):  
T Cell ◽  
Mouse Model ◽  
Lacrimal Gland ◽  
Regulatory T Cell ◽  
Diabetic Mouse ◽  
Sjögren Syndrome ◽  
Sjogren Syndrome ◽  
Cell Dysfunction ◽  
T Cell Dysfunction ◽  
Male Specific

scholarly journals CD8 T cells contribute to lacrimal gland pathology in the nonobese diabetic mouse model of Sjögren syndrome

2017 ◽  
Vol 95 (8) ◽  
pp. 684-694 ◽  
Author(s):  
Jennifer Y Barr ◽  
Xiaofang Wang ◽  
David K Meyerholz ◽  
Scott M Lieberman
Keyword(s):  
T Cells ◽  
Mouse Model ◽  
Lacrimal Gland ◽  
Cd8 T Cells ◽  
Diabetic Mouse ◽  
Sjögren Syndrome ◽  
Sjogren Syndrome ◽  
Nonobese Diabetic Mouse ◽  
Nonobese Diabetic

scholarly journals Mechanisms of PD-L1/PD-1–mediated CD8 T-cell dysfunction in the context of aging-related immune defects in the Eµ-TCL1 CLL mouse model

Blood ◽  
2015 ◽  
Vol 126 (2) ◽  
pp. 212-221 ◽  
Author(s):  
Fabienne McClanahan ◽  
John C. Riches ◽  
Shaun Miller ◽  
William P. Day ◽  
Eleni Kotsiou ◽  
...  
Keyword(s):  
T Cells ◽  
T Cell ◽  
Mouse Model ◽  
Cd8 T Cell ◽  
Effector Functions ◽  
Cell Dysfunction ◽  
Key Points ◽  
T Cell Dysfunction ◽  
Immune Defects

Key Points PD-L1/PD-1–mediated CD8 T-cell dysfunction develops with CLL in different organs, and similarities to aging-related immune defects exist. PD-1+ normal T cells have markedly different effector functions than PD-1+ CLL T cells.

scholarly journals Exacerbation of Endometriosis Due To Regulatory T-Cell Dysfunction

2017 ◽  
Vol 102 (9) ◽  
pp. 3206-3217 ◽  
Author(s):  
Yukiko Tanaka ◽  
Taisuke Mori ◽  
Fumitake Ito ◽  
Akemi Koshiba ◽  
Osamu Takaoka ◽  
...  
Keyword(s):  
T Cell ◽  
Regulatory T Cell ◽  
Cell Dysfunction ◽  
T Cell Dysfunction

scholarly journals In colorectal cancer mast cells contribute to systemic regulatory T-cell dysfunction

2010 ◽  
Vol 107 (14) ◽  
pp. 6430-6435 ◽  
Author(s):  
N. R. Blatner ◽  
A. Bonertz ◽  
P. Beckhove ◽  
E. C. Cheon ◽  
S. B. Krantz ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
T Cell ◽  
Mast Cells ◽  
Regulatory T Cell ◽  
Cell Dysfunction ◽  
T Cell Dysfunction

scholarly journals Regulatory T cell dysfunction in type 1 diabetes: what’s broken and how can we fix it?

Diabetologia ◽  
2017 ◽  
Vol 60 (10) ◽  
pp. 1839-1850 ◽  
Author(s):  
Caroline M. Hull ◽  
Mark Peakman ◽  
Timothy I. M. Tree
Keyword(s):  
Type 1 Diabetes ◽  
T Cell ◽  
Regulatory T Cell ◽  
Cell Dysfunction ◽  
T Cell Dysfunction

scholarly journals Regulatory T cell dysfunction in subjects with common variable immunodeficiency complicated by autoimmune disease

2009 ◽  
Vol 131 (2) ◽  
pp. 240-253 ◽  
Author(s):  
Grace P. Yu ◽  
David Chiang ◽  
Steven J. Song ◽  
Elisabeth G. Hoyte ◽  
Jennifer Huang ◽  
...  
Keyword(s):  
T Cell ◽  
Autoimmune Disease ◽  
Common Variable Immunodeficiency ◽  
Regulatory T Cell ◽  
Cell Dysfunction ◽  
T Cell Dysfunction ◽  
Common Variable

scholarly journals Development of Inflammatory Bowel Disease in Long-Evans Cinnamon Rats Based on CD4+CD25+Foxp3+ Regulatory T Cell Dysfunction

2008 ◽  
Vol 180 (10) ◽  
pp. 6997-7008 ◽  
Author(s):  
Naozumi Ishimaru ◽  
Akiko Yamada ◽  
Masayuki Kohashi ◽  
Rieko Arakaki ◽  
Tetsuyuki Takahashi ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
T Cell ◽  
Bowel Disease ◽  
Regulatory T Cell ◽  
Cell Dysfunction ◽  
T Cell Dysfunction ◽  
Inflammatory Bowel ◽  
Long Evans
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