Low serum albumin levels predict short‐ and long‐term mortality risk in patients hospitalised to general surgery wards

2020 ◽  
Vol 50 (8) ◽  
pp. 977-984 ◽  
Author(s):  
Amit Akirov ◽  
Alexander Gorshtein ◽  
Chagit Adler‐Cohen ◽  
Tali Steinmetz ◽  
Tzipora Shochat ◽  
...  
Keyword(s):  
Serum Albumin ◽  
Mortality Risk ◽  
General Surgery ◽  
Short And Long Term ◽  
Low Serum ◽  
Long Term Mortality

Short- and Long-term Mortality Risk After Acute Pulmonary Embolism

2018 ◽  
Vol 20 (12) ◽  
Author(s):  
Rajesh Gupta ◽  
Dylan D. Fortman ◽  
Daniel R. Morgenstern ◽  
Christopher J. Cooper
Keyword(s):  
Pulmonary Embolism ◽  
Mortality Risk ◽  
Acute Pulmonary Embolism ◽  
Short And Long Term ◽  
Long Term Mortality

Short- and Long-term Mortality Risk Associated with the Use of Antipsychotics Among 26,940 Dementia Outpatients: A Population-Based Study

2014 ◽  
Vol 22 (4) ◽  
pp. 321-331 ◽  
Author(s):  
Ellen Melbye Langballe ◽  
Bo Engdahl ◽  
Hedvig Nordeng ◽  
Clive Ballard ◽  
Dag Aarsland ◽  
...  
Keyword(s):  
Mortality Risk ◽  
Population Based ◽  
Population Based Study ◽  
Short And Long Term ◽  
Long Term Mortality

Elevated asymmetric dimethylarginine levels predict short- and long-term mortality risk in critically ill patients

2013 ◽  
Vol 28 (6) ◽  
pp. 947-953 ◽  
Author(s):  
Alexander Koch ◽  
Ralf Weiskirchen ◽  
Julian Kunze ◽  
Hanna Dückers ◽  
Jan Bruensing ◽  
...  
Keyword(s):  
Critically Ill ◽  
Mortality Risk ◽  
Critically Ill Patients ◽  
Asymmetric Dimethylarginine ◽  
Short And Long Term ◽  
Long Term Mortality

scholarly journals Impacts of admission serum albumin levels on short-term and long-term mortality in hospitalized patients

QJM ◽  
2019 ◽  
Vol 113 (6) ◽  
pp. 393-398 ◽  
Author(s):  
C Thongprayoon ◽  
W Cheungpasitporn ◽  
A Chewcharat ◽  
M A Mao ◽  
S Thirunavukkarasu ◽  
...  
Keyword(s):  
Hospital Mortality ◽  
Serum Albumin ◽  
Hospital Stay ◽  
Reference Group ◽  
Albumin Level ◽  
Hospitalized Patients ◽  
Tertiary Referral Hospital ◽  
Short And Long Term ◽  
Long Term Mortality

Abstract Aim The aim of this study is to assess the association between admission serum albumin and short- and long-term mortality in all hospitalized patients. Design A single-center cohort study. Methods A retrospective cohort of all adult hospitalized patients at a tertiary referral hospital between January 2009 and December 2013 were analysed. Admission serum albumin was stratified into six groups: ≤2.4, 2.5–2.9, 3.0–3.4, 3.5–3.9, 4.0–4.4 and ≥4.5 g/dl. The outcomes of interest were in-hospital mortality, length of hospital stay and 1-year mortality. Serum albumin of 4–4.4 g/dl was selected as a reference group for outcome comparison. Results A total of 14 075 patients were studied. Admission serum albumin of ≥4.5 g/dl had the lowest in-hospital and 1-year mortality with progressively increased in-hospital mortality observed with decreased admission serum albumin. In adjusted analysis, compared with serum albumin of 4.0–4.4 g/dl, serum albumin of ≤2.4, 2.5–2.9, 3.0–3.4 and 3.5–3.9 were significantly associated with increased in-hospital and 1-year mortality. In contrast, serum albumin of ≥4.5 g/dl was significantly associated with lower 1-year mortality but not in-hospital mortality. Admission serum albumin <4.0 g/dl was significantly associated with a prolonged hospital stay, while admission serum albumin of ≥4.5 g/dl was significantly associated with shorter hospital stay, compared with serum albumin of 4.0–4.4 g/dl. Conclusion Low albumin level at admission was progressively associated with increased short- and long-term mortality in all hospitalized patients even when albumin level was considered in normal range.

scholarly journals Effect of day of the week on short- and long-term mortality after emergency general surgery

2017 ◽  
Vol 104 (7) ◽  
pp. 936-945 ◽  
Author(s):  
M. A. Gillies ◽  
N. I. Lone ◽  
R. M. Pearse ◽  
C. Haddow ◽  
L. Smyth ◽  
...  
Keyword(s):  
General Surgery ◽  
Emergency General Surgery ◽  
Short And Long Term ◽  
Day Of The Week ◽  
Long Term Mortality

scholarly journals Antipsychotics and mortality among elderly with dementia: a population based study in the Lazio region

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
A M Bargagli ◽  
S Cascini ◽  
N Agabiti ◽  
U Kirchmayer ◽  
C Marino ◽  
...  
Keyword(s):  
Mortality Risk ◽  
Index Date ◽  
Nearest Neighbor ◽  
Drug Prescription ◽  
Lazio Region ◽  
Dementia Patients ◽  
Short And Long Term ◽  
The Impact ◽  
Long Term Mortality

Abstract Background Most dementia patients experience one or more behavioral and psychological symptoms (BPSD) at some time during their illness, in particular in the middle and later stages. Antipsychotic drugs (AP) are often prescribed off-label for treating BPSD, despite concerns about safety and limited efficacy. The impact of AP on short- and long-term mortality has not been fully assessed. Objective To assess the association between the use of APs and short- and long-term mortality in a cohort of dementia patients aged ≥ 65 years residing in the Lazio region. Methods We use data from regional health information systems to conduct a retrospective age, gender and comorbidity matched cohort study with a 1:3 matching ratio to pair dementia patients new AP users with non-users. For the exposed participants, the index date was defined as the date of the first drug prescription; the same date was used for non-users matched subjects. Patients were enrolled on 31/12/2016 and followed-up from the index date through 2018. Four cohorts were enrolled to analyze mortality at 30, 60, 180 and 65 days from the index date. Adjusted estimates were obtained with propensity score matching using the Greedy Nearest Neighbor Matching algorithm. Results We enrolled 34,625 individuals (67% females, mean age 82 years) distributed as follows: 30 days cohort, 4321 users vs 12,960 non-users; 60 days cohort, 4202 users vs 12,606 non-users; 180 days cohort, 3641 users vs 19,923 non-users; 365 days cohort, 2618 users vs 7854 non-users. Multivariate analyses showed a statistically significant excess mortality at 60, 180, and 365 days since the first prescription (HR: 1.83, HR: 1.63, and HR: 1.62, respectively). Conclusions This study showed that antipsychotics increase short- and long-term mortality risk in older adults with dementia. The prescription of AP should be carefully evaluated and, if it is the best option for patient and caregiver, stringently monitored. Key messages Antipsychotic medication use is associated with an increased all-cause mortality in elderly with dementia. The mortality risk increases in 60 days after starting their use and remains elevated at 1 year.

scholarly journals Cystatin C predicts long term mortality better than creatinine in a nationwide study of intensive care patients

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Johanna Helmersson-Karlqvist ◽  
Miklos Lipcsey ◽  
Johan Ärnlöv ◽  
Max Bell ◽  
Bo Ravn ◽  
...  
Keyword(s):  
Intensive Care ◽  
Critically Ill ◽  
Risk Prediction ◽  
Cystatin C ◽  
Mortality Risk ◽  
Critically Ill Patients ◽  
Cox Regression ◽  
Sample Tube ◽  
Long Term Mortality

AbstractDecreased glomerular filtration rate (GFR) is linked to poor survival. The predictive value of creatinine estimated GFR (eGFR) and cystatin C eGFR in critically ill patients may differ substantially, but has been less studied. This study compares long-term mortality risk prediction by eGFR using a creatinine equation (CKD-EPI), a cystatin C equation (CAPA) and a combined creatinine/cystatin C equation (CKD-EPI), in 22,488 patients treated in intensive care at three University Hospitals in Sweden, between 2004 and 2015. Patients were analysed for both creatinine and cystatin C on the same blood sample tube at admission, using accredited laboratory methods. During follow-up (median 5.1 years) 8401 (37%) patients died. Reduced eGFR was significantly associated with death by all eGFR-equations in Cox regression models. However, patients reclassified to a lower GFR-category by using the cystatin C-based equation, as compared to the creatinine-based equation, had significantly higher mortality risk compared to the referent patients not reclassified. The cystatin C equation increased C-statistics for death prediction (p < 0.001 vs. creatinine, p = 0.013 vs. combined equation). In conclusion, this data favours the sole cystatin C equation rather than the creatinine or combined equations when estimating GFR for risk prediction purposes in critically ill patients.

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