The nuclear hormone receptor E75A regulates vitellogenin gene (Al-Vg ) expression in the mirid bug Apolygus lucorum

2017 ◽  
Vol 27 (2) ◽  
pp. 188-197 ◽  
Author(s):  
Y.-A. Tan ◽  
X.-D. Zhao ◽  
Y. Sun ◽  
D.-J. Hao ◽  
J. Zhao ◽  
...  
Keyword(s):  
Hormone Receptor ◽  
Nuclear Hormone Receptor ◽  
Apolygus Lucorum ◽  
Vitellogenin Gene ◽  
Mirid Bug

scholarly journals Phosphorylation of the Hinge Domain of the Nuclear Hormone Receptor LRH-1 Stimulates Transactivation

2006 ◽  
Vol 281 (12) ◽  
pp. 7850-7855 ◽  
Author(s):  
Yoon-Kwang Lee ◽  
Yun-Hee Choi ◽  
Steven Chua ◽  
Young Joo Park ◽  
David D. Moore
Keyword(s):  
Hormone Receptor ◽  
Nuclear Hormone Receptor ◽  
Hinge Domain

scholarly journals Pseudoginsenoside F11, a Novel Partial PPARγAgonist, Promotes Adiponectin Oligomerization and Secretion in 3T3-L1 Adipocytes

PPAR Research ◽  
2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Guoyu Wu ◽  
Junyang Yi ◽  
Ling Liu ◽  
Pengcheng Wang ◽  
Zhijie Zhang ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Side Effects ◽  
Hormone Receptor ◽  
Adipocyte Differentiation ◽  
American Ginseng ◽  
Nuclear Hormone Receptor ◽  
Targeted Therapeutics ◽  
Panax Quinquefolium ◽  
Master Regulator

PPARγis a nuclear hormone receptor that functions as a master regulator of adipocyte differentiation and development. Full PPARγagonists, such as the thiazolidinediones (TZDs), have been widely used to treat type 2 diabetes. However, they are characterized by undesirable side effects due to their strong agonist activities. Pseudoginsenoside F11 (p-F11) is an ocotillol-type ginsenoside isolated fromPanax quinquefolium L.(American ginseng). In this study, we found that p-F11 activates PPARγwith modest adipogenic activity. In addition, p-F11 promotes adiponectin oligomerization and secretion in 3T3-L1 adipocytes. We also found that p-F11 inhibits obesity-linked phosphorylation of PPARγat Ser-273 by Cdk5. Therefore, p-F11 is a novel partial PPARγagonist, which might have the potential to be developed as a new PPARγ-targeted therapeutics for type 2 diabetes.

Inhibition of nuclear hormone receptor activity by calreticulin

Nature ◽  
1994 ◽  
Vol 367 (6462) ◽  
pp. 480-483 ◽  
Author(s):  
Shoukat Dedhar ◽  
Paul S. Rennie ◽  
Mary Shago ◽  
Chung-Yee Leung Hagesteijn ◽  
Huiling Yang ◽  
...  
Keyword(s):  
Hormone Receptor ◽  
Nuclear Hormone Receptor ◽  
Receptor Activity
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