Pre‐transurethral prostate resection anxiety on postoperative pain and sleep quality: A correlational study

Author(s):  
Seda Atay ◽  
Aylin Aydin Sayilan
2016 ◽  
Vol 125 (6) ◽  
pp. 1513-1522 ◽  
Author(s):  
Nir Shimony ◽  
Uri Amit ◽  
Bella Minz ◽  
Rachel Grossman ◽  
Marc A. Dany ◽  
...  

OBJECTIVE The aim of this study was to assess in-hospital (immediate) postoperative pain scores and analgesic consumption (primary goals) and preoperative anxiety and sleep quality (secondary goals) in patients who underwent craniotomy and were treated with pregabalin (PGL). Whenever possible, out-of-hospital pain scores and analgesics usage data were obtained as well. METHODS This prospective, randomized, double-blind and controlled study was conducted in consenting patients who underwent elective craniotomy for brain tumor resection at Tel Aviv Medical Center between 2012 and 2014. Patients received either 150 mg PGL (n = 50) or 500 mg starch (placebo; n = 50) on the evening before surgery, 1.5 hours before surgery, and twice daily for 72 hours following surgery. All patients spent the night before surgery in the hospital, and no other premedication was administered. Opioids and nonsteroidal antiinflammatory drugs were used for pain, which was self-rated by means of a numerical rating scale (score range 0–10). RESULTS Eighty-eight patients completed the study. Data on the American Society of Anesthesiologists class, age, body weight, duration of surgery, and intraoperative drugs were similar for both groups. The pain scores during postoperative Days 0 to 2 were significantly lower in the PGL group than in the placebo group (p < 0.01). Analgesic consumption was also lower in the PGL group, both immediately and 1 month after surgery. There were fewer requests for antiemetics in the PGL group, and the rate of postoperative nausea and vomiting was lower. The preoperative anxiety level and the quality of sleep were significantly better in the PGL group (p < 0.01). There were no PGL-associated major adverse events. CONCLUSIONS Perioperative use of twice-daily 150 mg pregabalin attenuates preoperative anxiety, improves sleep quality, and reduces postoperative pain scores and analgesic usage without increasing the rate of adverse effects. Clinical trial registration no.: NCT01612832 (clinicaltrials.gov)


2020 ◽  
Vol 55 ◽  
pp. 141-146
Author(s):  
Sara Gholami ◽  
Leila Khanali Mojen ◽  
Maryam Rassouli ◽  
Bagher Pahlavanzade ◽  
Azam Shirinabadi Farahani

2015 ◽  
Vol 16 (1) ◽  
pp. 40-50
Author(s):  
Hong-Gu He ◽  
Piyanee Klainin-Yobas ◽  
Emily Neo Kim Ang ◽  
Rajammal Sinnappan ◽  
Tarja Pölkki ◽  
...  

2021 ◽  
Vol 15 (4) ◽  
pp. 484-494
Author(s):  
Dennis Boye Larsen ◽  
Mogens Laursen ◽  
Ole Simonsen ◽  
Lars Arendt-Nielsen ◽  
Kristian Kjær Petersen

Background: Chronic postoperative pain following total joint replacement (TJA) is a substantial clinical problem, and poor sleep may affect predictive factors for postoperative pain, such as pain catastrophizing. However, the magnitude of these associations is currently unknown. This exploratory study investigated (1) the relationship between preoperative sleep quality, clinical pain intensity, pain catastrophizing, anxiety, and depression and (2) their associations with chronic postoperative pain following TJA. Methods: This secondary analysis from a larger randomized controlled trial included rest pain intensity (preoperative and 12 months postoperative; visual analogue scale, VAS), preoperative Pittsburgh Sleep Quality Index (PSQI), Pain Catastrophizing Scale (PCS), Hospital Anxiety and Depression Scale (HADS) data from 74 knee and 89 hip osteoarthritis (OA) patients scheduled for TJA. Poor sleepers were identified based on preoperative PSQI scores higher than 5. Results: Poor sleepers demonstrated higher preoperative VAS, pain catastrophizing, anxiety, and depression compared with good sleepers (all p < 0.003). Preoperative PSQI (β = 0.23, p = 0.006), PCS (β = 0.44, p < 0.005), and anxiety (β = 0.18, p = 0.036) were independent factors for preoperative VAS. Preoperative VAS (β = 0.32, p < 0.005), but not preoperative sleep quality (β = −0.06, p = 0.5), was an independent factor for postoperative VAS. Conclusion: The OA patients reporting poor preoperative sleep quality show higher preoperative pain, pain catastrophizing, anxiety, and depression. High preoperative pain intensity, but not poor sleep quality, was associated with higher chronic postoperative pain intensity. Future studies are encouraged to explore associations between sleep and chronic postoperative pain.


Author(s):  
Zhi-Wen Yao ◽  
Bing-Cheng Zhao ◽  
Xiao Yang ◽  
Shao-Hui Lei ◽  
Yu-Mei Jiang ◽  
...  

Abstract Purpose Our study was designed to examine the possible relationship between gut microbiota, sleep disturbances, and acute postoperative pain. Methods Using 16S rRNA sequencing, we analyzed preoperative fecal samples from women undergoing breast cancer surgery. Preoperative sleep disturbance was evaluated with the Pittsburgh Sleep Quality Index (PSQI) questionnaire. Peak and average pain at rest and movement were evaluated 24 h after surgery, using a numerical rating scale (NRS). Preoperative symptoms of depression and anxiety were assessed with the Patient Health Questionnaire-9 (PHQ-9) and Generalized Anxiety Disorder-7 (GAD-7), respectively. Inflammation was measured using white blood cell and neutrophil counts, together with platelet-lymphocyte ratio, and neutrophil-lymphocyte ratio. Results Preoperative sleep disturbance was associated with more severe acute postoperative pain. At the phylum level, women with poor sleep quality had higher relative abundance of Firmicutes (p = 0.021) and lower relative abundance of Bacteroidetes (p = 0.013). At the genus level, women with poor sleep quality harbored higher relative abundance of Acidaminococcus and lower relative abundance of several genera. The genus Alloprevotella was negatively associated with peak pain at movement during the first 24 h (r = − 0.592, p < 0.001). The genus Desulfovibrio was negatively associated with symptoms of anxiety (r = − 0.448, p = 0.006). However, partial correlations suggested that the relationship between Alloprevotella and peak pain at movement during the first 24 h was not statistically significant after controlling for sleep (r = − 0.134, p = 0.443). Conclusion These findings suggest that the changed gut microbiota may be involved in sleep-pain interaction and could be applied as a potential preventive method for postoperative pain. Trial registration The present clinical study has been registered on Chinese Clinical Trial Registry (www.chictr.org.cn); the clinical trial registration number is ChiCTR1900021730; the date of registration is March 7, 2019.


2021 ◽  
Vol 10 (9) ◽  
pp. 2000
Author(s):  
Reetta M. Sipilä ◽  
Eija A. Kalso

Sleep disturbance, pain, and having a surgical procedure of some kind are all very likely to occur during the average lifespan. Postoperative pain continues to be a prevalent problem and growing evidence supports the association between pain and sleep disturbances. The bidirectional nature of sleep and pain is widely acknowledged. A decline in sleep quality adds a risk for the onset of pain and also exacerbates existing pain. The risk factors for developing insomnia and experiencing severe pain after surgery are quite similar. The main aim of this narrative review is to discuss why it is important to be aware of sleep disturbances both before and after surgery, to know how sleep disturbances should be assessed and monitored, and to understand how better sleep can be supported by both pharmacological and non-pharmacological interventions.


2020 ◽  
Vol 68 (06) ◽  
pp. 498-502
Author(s):  
Qi-Liang Zhang ◽  
Ning Xu ◽  
Shu-Ting Huang ◽  
Ze-Wei Lin ◽  
Liang-Wan Chen ◽  
...  

Abstract Background To investigate the effect of music therapy on early postoperative pain, anxiety, and sleep quality in patients after mechanical mitral valve replacement (MVR). Methods A total of 222 patients undergoing mechanical MVR were divided into two groups: the music group and the control group. The patients in the music group received 30 minutes of music therapy every day, whereas the patients in the control group had 30 minutes of quiet time. The visual analogue scale (VAS) was used to evaluate the degree of pain, and the Self-Rating Anxiety Scale (SAS) was used to evaluate the degree of early postoperative anxiety. We also recorded the sleep duration of the patients and used the Verran and Snyder-Halpern (VSH) Sleep Scale to evaluate the sleep quality of the patients. Results The VAS scores in the music group were significantly lower than those in the control group, and early postoperative anxiety in the music group was also significantly improved compared with that in the control group. The sleep duration in the music group was significantly greater than that in the control group. In the evaluation of sleep quality using the VSH Sleep Scale, the scores for sleep interruption, sleep length, sleep depth, degree of rest, and subjective sleep quality in the music group were significantly lower than those in the control group. Conclusions Music therapy can be an effective intervention to reduce early postoperative pain, relieve early postoperative anxiety, prolong sleep time, and improve the sleep quality of patients after mechanical MVR.


Medicine ◽  
2019 ◽  
Vol 98 (44) ◽  
pp. e17708 ◽  
Author(s):  
Jin-ping Wang ◽  
Su-fen Lu ◽  
Li-na Guo ◽  
Chun-guang Ren ◽  
Zong-wang Zhang

2021 ◽  
Author(s):  
Bing Li ◽  
Yao Liu ◽  
Jia Jia ◽  
Fudong Tang ◽  
Wei Zhang ◽  
...  

Abstract BackgroundTo identify the risk factors of sleep disturbances in elderly patients after thoracic surgery.MethodsWe enrolled 200 patients, all aged > 65, who underwent elective thoracic surgery and had American Society of Anesthesiology physical status II–III. We recorded general information, surgical diagnosis, type of operation, surgical duration, bleeding, nerve block, and dexmedetomidine dose given by controlled intravenous analgesia (PCIA). We used the Pittsburgh Sleep Quality Index (PSQI) at the end of PCIA to evaluate subjective sleep quality; we also recorded postoperative pain, nausea, and vomiting. We divided patients into a non-sleep disturbances group and a sleep disturbances group with PSQI \(\ge\)5 as the cutoff.ResultsA total of 76 (45%) of the patients had sleep disturbances after thoracic surgery. There were significant differences between groups in terms of chronic insomnia, hypertension, diabetes, BMI, age, surgical diagnosis, type of operation, surgical duration, bleeding, nerve block, and dexmedetomidine dose in PCIA. Logistic regression analysis revealed that chronic insomnia, BMI, diabetes, surgical diagnosis, type of operation, surgical duration, bleeding, and postoperative pain were independent risk factors of postoperative sleep disturbances. This analysis also showed that nerve block and dexmedetomidine dose in PCIA were significant protective factors of postoperative sleep disturbances.ConclusionChronic insomnia, BMI, diabetes, surgical diagnosis, type of operation, surgical duration, bleeding, and postoperative pain are independent risk factors of postoperative sleep disturbances in elderly patients. Nerve block and the dose of dexmedetomidine in PCIA are protective.Trial registrationChiCTR2000035169; retrospectively registered on 01.08.2020.


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