Statins significantly alter urinary stone‐related urine biochemistry in calcium kidney stone patients with dyslipidemia

2020 ◽  
Vol 27 (10) ◽  
pp. 839-844
Author(s):  
Chan Jung Liu ◽  
Ho Shiang Huang
Keyword(s):  
Kidney Stone ◽  
Urinary Stone ◽  
Urine Biochemistry

scholarly journals Nutrition and Kidney Stone Disease

Nutrients ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 1917
Author(s):  
Roswitha Siener
Keyword(s):  
Kidney Stone ◽  
Fluid Intake ◽  
Stone Formation ◽  
Urinary Stone ◽  
Stone Disease ◽  
Urinary Stones ◽  
Dietary Therapy ◽  
Effective Prevention ◽  
Kidney Stone Disease ◽  
Nutrition And Diet

The prevalence of kidney stone disease is increasing worldwide. The recurrence rate of urinary stones is estimated to be up to 50%. Nephrolithiasis is associated with increased risk of chronic and end stage kidney disease. Diet composition is considered to play a crucial role in urinary stone formation. There is strong evidence that an inadequate fluid intake is the major dietary risk factor for urolithiasis. While the benefit of high fluid intake has been confirmed, the effect of different beverages, such as tap water, mineral water, fruit juices, soft drinks, tea and coffee, are debated. Other nutritional factors, including dietary protein, carbohydrates, oxalate, calcium and sodium chloride can also modulate the urinary risk profile and contribute to the risk of kidney stone formation. The assessment of nutritional risk factors is an essential component in the specific dietary therapy of kidney stone patients. An appropriate dietary intervention can contribute to the effective prevention of recurrent stones and reduce the burden of invasive surgical procedures for the treatment of urinary stone disease. This narrative review has intended to provide a comprehensive and updated overview on the role of nutrition and diet in kidney stone disease.

scholarly journals Biochemical urinalysis of healthy kidney and stone-generating kidney in unilateral urolithiasis

2019 ◽  
Vol 8 (2) ◽  
pp. 151-156
Author(s):  
Feramarz Mohammadalibeigi ◽  
Majid Shirani ◽  
Hamed Seyed-Salehi ◽  
Lotfollah Afzali
Keyword(s):  
Uric Acid ◽  
Kidney Stone ◽  
Stone Formation ◽  
Urinary Stone ◽  
Metabolic Factors ◽  
Cross Sectional ◽  
Urinary Sample ◽  
The Mean ◽  
The Difference ◽  
Southwest Iran

Introduction: Oxalate, calcium, uric acid, and citrate are among the most widely known biochemical factors for urinary stone formation. In most cases, urolithiasis occurs as unilateral despite the role of systemic metabolic factors in kidney stone formation. Objectives: The present research aimed to compare these urinary biochemical factors in healthy and stone-generating kidneys in patients with unilateral urolithiasis. Patients and Methods: Forty patients with unilateral urolithiasis participated in this cross-sectional, descriptive-analytical study. The patients were hospitalized in kidney surgery and kidney urology ward of Kashani hospital of Shahrekord, southwest Iran. After the implementation of crushing stone using transurethral lithotripsy (TUL), 5-10 cc of urinary sample was collected from each kidney. An AutoAnalyzer (Mindray Company, Bs–360 model) and laboratory kits (Bionic Company) were used to measure calcium, uric acid, and creatinine. Moreover, a manual method and Darman Faraz Kave company kits were applied to measure the levels of oxalate and citrate. Results on the healthy and stone-generating kidneys of each patient were separately analyzed using the Stata 13 software. Results: The difference in the mean ratio of uric acid, oxalate, and citrate to creatinine in the healthy kidneys and stone-generating kidneys was not significant. However, the mean UCa/UCr ratio in the healthy kidneys was 0.27±0.07 and relatively greater than that in the stone-generating kidneys (0.11±0.04) (P=0.06). Conclusion: The studied topical factors and secretory disorders had not any significant relationship with unilateral urolithiasis. The cause of unilateral urolithiasis should be searched in other factors such as metabolic factors, main positions of individual during 24 hours and sleeping, and anatomic disorders of kidney stone, or multifactorial.

scholarly journals Urinary stone characteristics of patients treated with extracorporeal shock wave lithotripsy in Cipto Mangunkusumo Hospital Jakarta, 2008–2014: a gender analysis

2015 ◽  
Vol 24 (4) ◽  
pp. 234-8 ◽  
Author(s):  
Endrika Noviandrini ◽  
Ponco Birowo ◽  
Nur Rasyid
Keyword(s):  
Shock Wave ◽  
Extracorporeal Shock Wave Lithotripsy ◽  
Kidney Stone ◽  
Shock Wave Lithotripsy ◽  
Urinary Stone ◽  
Urinary Stones ◽  
Extracorporeal Shock Wave ◽  
Common Location ◽  
Frequent Site ◽  
Stone Characteristics

Background: The incidence of urinary stone patient in Indonesia has increased every year in both genders. Data showed that urolithiasis was higher in male rather than female. The aimed of this study was to describe the characteristics of urinary stone found in patient who underwent extracorporeal shock wave lithotripsy (ESWL) at Cipto Mangunkusumo Hospital, Jakarta from 2008–2014. Methods: Data obtained from ESWL medical record Cipto Mangunkusumo Hospital, Jakarta from 2008–2014. We obtained 5,174 out of 6,020 data due to incompleteness data record. We sorted data records by gender, age, stone location, stone opacity, size of the stone, and history of ESWL, and analyzed by statistic tools (SPSS v 20 for Mac).Results: From 5,174 records, we found that the incidence of urinary stones was two times higher in male rather than female (66.3%:33.64%), occurred mostly in productive age (65.2% male, 65.9% female). Unilateral kidney stone was most common location found for both gender (50.2% male, 57.2% female), and most frequent site located in calyx inferior (24.8% male, 28.9% female). About 72.9% stone was radiopaque (73.7% male and 71.5% female). The mean size of the stone in male and female was 11.34±7.15 mm and 11.90±7.54 mm, respectively. This study also showed that 79.3% patients came for first ESWL.Conclusion: Urinary stone founds two times higher in male than female, and mostly occurs on their productive ages. Unilateral kidney stone in calyx inferior become the most common stone found in both gender. Most of the stone has radiopaque opacity.

Urinary stone risk factors in the descendants of patients with kidney stone disease

2018 ◽  
Vol 33 (7) ◽  
pp. 1173-1181 ◽  
Author(s):  
Thasinas Dissayabutra ◽  
Nuttiya Kalpongkul ◽  
Jakkhaphan Rattanaphan ◽  
Chanchai Boonla ◽  
Monpicha Srisa-art ◽  
...  
Keyword(s):  
Risk Factors ◽  
Kidney Stone ◽  
Urinary Stone ◽  
Stone Disease ◽  
Kidney Stone Disease

scholarly journals A clinical example of percutaneous nephrolitolapaxy of complete staghorn kidney stone in patient with lumbar renal dystopia

2021 ◽  
Vol 6 ◽  
pp. 94-98
Author(s):  
A.G. Berezhnoy ◽  
◽  
S.S. Dunaevskaya ◽  
A.V. Ershov ◽  
◽  
...  
Keyword(s):  
Kidney Stone ◽  
Urinary Stone ◽  
Upper Urinary Tract ◽  
Stone Disease ◽  
Percutaneous Surgery ◽  
Urinary Stone Disease ◽  
Shape Structure ◽  
Working Age ◽  
Renal Abnormalities ◽  
Comprehensive Study

Urinary stone disease (urolithiasis, UL) is one of the most prevalent diseases in the world affecting almost 3% of the population, mainly people of working age from 40 to 50 years, which determines the relevance of a comprehensive study of this disease. Meanwhile, few works devoted to the interrelation between UL and renal abnormalities have been published. The unusual nature of angioarchitectonics, location, shape, structure, number of kidneys and upper urinary tract make it difficult to perform both open and endoscopic surgery thus preconditioning the reduction of their effectiveness and increasing the number of complications. In recent years, the number of indications for open stone surgery has significantly decreased. Percutaneous surgery has become widely used in endourology, including treatment of abnormal kidneys. However, the issues of percutaneous nephrolitolapaxy (PCNL) in kidney abnormalities have not been completely resolved yet. The article presents a clinical case of successful percutaneous nephrolitolapaxy of complete coral-shaped kidney stone (Class 4) in a patient with lumbar renal dystopia.

scholarly journals Calcium Kidney Stones are Associated with Increased Risk of Carotid Atherosclerosis: The Link between Urinary Stone Risks, Carotid Intima-Media Thickness, and Oxidative Stress Markers

2020 ◽  
Vol 9 (3) ◽  
pp. 729
Author(s):  
Ho Shiang Huang ◽  
Pao Chi Liao ◽  
Chan Jung Liu
Keyword(s):  
Kidney Stones ◽  
Kidney Stone ◽  
Carotid Atherosclerosis ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Urinary Stone ◽  
Carotid Imt ◽  
Media Thickness ◽  
Stone Formers ◽  
Increased Risk

Previous studies have suggested that kidney stone formers are associated with a higher risk of cardiovascular events. To our knowledge, there have been no previous examinations of the relationship between carotid intima-media thickness (IMT) and urinary stone risk factors. This study was aimed toward an investigation of the association between dyslipidemia, IMT, and 24-hour urinalysis in patients with calcium oxalate (CaOx) or calcium phosphate (CaP) stones. We prospectively enrolled 114 patients with kidney stones and 33 controls between January 2016 and August 2016. All patients were divided into four groups, according to the stone compositions—CaOx ≥ 50% group, CaP group, struvite group, and uric acid stones group. Carotid IMT and the carotid score (CS) were evaluated using extracranial carotid artery doppler ultrasonography. The results of a multivariate analysis indicated that a higher serum total cholesterol (TC) and low-density lipoprotein (LDL) were all associated with lower urinary citrate and higher CS in both the CaOx ≥ 50% and CaP groups. Higher serum TC and LDL were also associated with increased serum 8-OHdG levels in both groups. The levels of carotid IMT and CS in the CaOx ≥ 50% and CaP groups were all significantly higher than in the controls. These findings suggest a strong link between dyslipidemia, carotid atherosclerosis, and calcium kidney stone disease.

scholarly journals Kidney Stone Disease: An Update on Current Concepts

2018 ◽  
Vol 2018 ◽  
pp. 1-12 ◽  
Author(s):  
Tilahun Alelign ◽  
Beyene Petros
Keyword(s):  
Kidney Stone ◽  
Stone Formation ◽  
Research Area ◽  
Urinary Stone ◽  
Stone Disease ◽  
New Drugs ◽  
Mitogen Activated Protein Kinase ◽  
World Population ◽  
Kidney Stone Disease ◽  
Increased Risk

Kidney stone disease is a crystal concretion formed usually within the kidneys. It is an increasing urological disorder of human health, affecting about 12% of the world population. It has been associated with an increased risk of end-stage renal failure. The etiology of kidney stone is multifactorial. The most common type of kidney stone is calcium oxalate formed at Randall’s plaque on the renal papillary surfaces. The mechanism of stone formation is a complex process which results from several physicochemical events including supersaturation, nucleation, growth, aggregation, and retention of urinary stone constituents within tubular cells. These steps are modulated by an imbalance between factors that promote or inhibit urinary crystallization. It is also noted that cellular injury promotes retention of particles on renal papillary surfaces. The exposure of renal epithelial cells to oxalate causes a signaling cascade which leads to apoptosis by p38 mitogen-activated protein kinase pathways. Currently, there is no satisfactory drug to cure and/or prevent kidney stone recurrences. Thus, further understanding of the pathophysiology of kidney stone formation is a research area to manage urolithiasis using new drugs. Therefore, this review has intended to provide a compiled up-to-date information on kidney stone etiology, pathogenesis, and prevention approaches.

Sign in / Sign up

Export Citation Format

Share Document