scholarly journals Long‐term safety and efficacy of antimuscarinic add‐on therapy in patients with overactive bladder who had a suboptimal response to mirabegron monotherapy: A multicenter, randomized study in Japan (MILAI II study)

2018 ◽  
Vol 26 (3) ◽  
pp. 342-352 ◽  
Author(s):  
Osamu Yamaguchi ◽  
Hidehiro Kakizaki ◽  
Yukio Homma ◽  
Yasuhiko Igawa ◽  
Masayuki Takeda ◽  
...  
Keyword(s):  
Overactive Bladder ◽  
Randomized Study ◽  
Safety And Efficacy

Long-Term Safety and Efficacy of Solifenacin in Children and Adolescents with Overactive Bladder

2017 ◽  
Vol 198 (4) ◽  
pp. 928-936 ◽  
Author(s):  
Donald Newgreen ◽  
Brigitte Bosman ◽  
Adriana Hollestein-Havelaar ◽  
Ellen Dahler ◽  
Robin Besuyen ◽  
...  
Keyword(s):  
Overactive Bladder ◽  
Children And Adolescents ◽  
Safety And Efficacy

scholarly journals Trabeculectomy with Ologen implant versus perfluoropropane gas bubble for open angle glaucoma in pseudophakic eyes

2021 ◽  
Vol 14 (4) ◽  
pp. 510-516
Author(s):  
Ahmed S Elwehidy ◽  
◽  
Hossam Youssef Abouelkheir ◽  
Waleed Abou Samra ◽  
Faried M Wagdy ◽  
...  
Keyword(s):  
Open Angle Glaucoma ◽  
Randomized Study ◽  
Study Groups ◽  
Gas Bubble ◽  
Open Angle ◽  
Safety And Efficacy ◽  
Group I ◽  
The Mean

AIM: To evaluate the safety and efficacy of augmented trabeculotomy with Ologen versus perfluoropropane in management of pseudophakic glaucoma. METHODS: This is a comparative randomized study included 57 pseudophakic eyes of 57 patients with medically uncontrolled open angle glaucoma (OAG). Twenty-nine patients were allocated in group I (trabeculectomy with Ologen; trab-ologen group), while 28 patients were assigned in group II (trabeculectomy with perfluoropropane gas bubble; trab-C3F8 gas bubble group). RESULTS: The intraocular pressure (IOP) was significantly reduced in both study groups at all postoperative follow up intervals (1wk, 3, 6, 12, 18, 24, 30 and 36mo, P<0.001). The differences between the mean IOP values of both groups remained statistically insignificance during the early 12 months of follow up. However, the trab-ologen group achieved a statistically significant reduction over the trab-C3F8 gas bubble group during the last 24 months of follow up. CONCLUSION: Augmentation of trabeculectomy with either Ologen implant or perfluoropropane gas bubble are associated with strict long term IOP control and evident safety in medically-uncontrolled pseudophakic eyes with OAG.

scholarly journals Long-term Safety and Efficacy of Mirabegron and Solifenacin in Combination Compared with Monotherapy in Patients with Overactive Bladder: A Randomised, Multicentre Phase 3 Study (SYNERGY II)

2018 ◽  
Vol 74 (4) ◽  
pp. 501-509 ◽  
Author(s):  
Christian Gratzke ◽  
Rob van Maanen ◽  
Christopher Chapple ◽  
Paul Abrams ◽  
Sender Herschorn ◽  
...  
Keyword(s):  
Overactive Bladder ◽  
Phase 3 ◽  
Safety And Efficacy ◽  
Multicentre Phase

683 Randomised, double-blind, active-controlled phase III study to assess the long-term safety and efficacy of mirabegron in overactive bladder (OAB)

2012 ◽  
Vol 11 (1) ◽  
pp. e683-e683a ◽  
Author(s):  
C.R. Chapple ◽  
S. Kaplan ◽  
H.D. Mitcheson ◽  
J. Klecka ◽  
J. Cummings ◽  
...  
Keyword(s):  
Overactive Bladder ◽  
Phase Iii ◽  
Double Blind ◽  
Safety And Efficacy ◽  
Phase Iii Study
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