Features, risk factors and clinical outcome of “very late” recurrences after surgery for localized renal carcinoma: A retrospective evaluation of a cohort with a minimum of 10 years of follow up

2015 ◽  
Vol 23 (1) ◽  
pp. 36-40 ◽  
Author(s):  
Alessandro Antonelli ◽  
Maria Furlan ◽  
Mario Sodano ◽  
Luca Cindolo ◽  
Sandra Belotti ◽  
...  
Keyword(s):  
Risk Factors ◽  
Clinical Outcome ◽  
Renal Carcinoma ◽  
Retrospective Evaluation

scholarly journals Early and Midterm Outcome of TEVAR for Thoracic Aortic Pseudoaneurysm

2021 ◽  
Author(s):  
Hui Wang ◽  
Tun Wang ◽  
Hao He ◽  
Xin Li ◽  
Yuan Peng ◽  
...  
Keyword(s):  
Risk Factors ◽  
Clinical Outcome ◽  
Cardiac Disease ◽  
Cox Regression ◽  
Cox Regression Analysis ◽  
Aortic Pseudoaneurysm ◽  
Significant Difference ◽  
Independent Risk Factors ◽  
The Mean

Abstract Backgrounds: The prognosis of thoracic aortic pseudoaneurysm (TAP) after thoracic endovascular aortic repair (TEVAR) remains unclear. This study investigates the early and midterm clinical outcome as well as relevant risk factors of TAP patients following TEVAR therapy.Methods: From July 2010 to July 2020, 37 eligible TAP patients who underwent TEVAR were selected into our research. We retrospectively explored their baseline, perioperative and follow-up data. Fisher exact test and Kaplan-Meier method were applied for comparing difference between groups. Risk factors of late survival were discerned using Cox regression analysis.Results: There were 29 men and 12 women, with the mean age as 59.5±13.0 years (range, 30-82). The mean follow-up time was 30.7±28.3 months (range, 1-89). For early result, early mortality (≦30days) happened in 3(8.1%) zone 3 TAP patients versus 0 in zone 4 (p= 0.028); acute arterial embolism of lower extremity and type II endoleak respectively occurred in 1(2.7%) case. For midterm result, survival at 3 months, 1 year and 5 years was 88.8±5.3%, 75.9±7.5% and 68.3±9.9%, which showed significant difference between zone 2/3 versus zone 4 group (56.3±14.8% versus 72.9±13.2%, p= 0.013) and emergent versus elective TEVAR groups (0.0±0.0% versus 80.1±8.0%, p= 0.049). On multivariate Cox regression, lesions at zone 2/3 (HR 4.605, 95%CI 1.095-19.359), concomitant cardiac disease (HR 4.932, 95%CI 1.086-22.403) and emergent TEVAR (HR 4.196, 95%CI 1.042-16.891) were significant independent risk factors for worse late clinical outcome. Conclusions: TEVAR therapy is effective and safe with satisfactory early and midterm clinical outcome for TAP patients. Lesions at zone 2/3, concomitant cardiac disease and emergent TEVAR were independent risk factors for midterm survival outcome.

Retrospective evaluation of occlusion of patent ductus arteriosus with hemoclips in 20 dogs

2000 ◽  
Vol 36 (6) ◽  
pp. 548-555 ◽  
Author(s):  
LB Corti ◽  
D Merkley ◽  
OL Nelson ◽  
WA Ware
Keyword(s):  
Clinical Outcome ◽  
Patent Ductus Arteriosus ◽  
Left Atrial ◽  
Ductus Arteriosus ◽  
Retrospective Evaluation ◽  
Good Clinical Outcome ◽  
Heart Size ◽  
Fractional Shortening ◽  
Patent Ductus

Twenty dogs with patent ductus arteriosus occluded with Hemoclips were evaluated with a mean follow-up time of 799.4 days (range, 83 to 3,580 days). Significant decreases were found between pre- and postsurgical means for vertebral heart size and for echocardiographic left atrial/aortic-root ratios and percent fractional shortening (%FS). Despite a good clinical outcome, six of 20 dogs had persistent cardiomyopathy of overload with diminished %FS (28% or less) at follow-up. One dog had residual ductal flow identified five days postoperatively. Subsequent evaluations in this case at 60, 144, 226, 344, and 560 days postoperatively demonstrated gradually diminishing ductal flow. The remaining 19 dogs did not recanalize.

Abstract 2942: Clinical Outcome in Patients with NonCalcified Coronary Plaque Detected by Multi Slice Computed Tomography: Risk Factors, Stenosis and 34-month Clinical Outcome.

Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Niti R Aggarwal ◽  
Thomas Knickelbine ◽  
Aaron Tande ◽  
Luke Solftus ◽  
John Lesser ◽  
...  
Keyword(s):  
Risk Factors ◽  
Computed Tomography ◽  
Clinical Outcome ◽  
Coronary Stenosis ◽  
List Type ◽  
Cardiac Events ◽  
Conventional Risk Factor ◽  
Significant Stenosis ◽  
Calcified Plaque

Background: Contrast enhanced Multislice Computed Tomography (MSCTA) can detect non-calcified plaque (NCP) in coronary arteries and associated coronary stenosis. However, the clinical impact of NCP is not well defined. This study examined the relationship of patient risk factors with NCP detected by MSCTA, and 34 month clinical follow-up. Methods: From September 2003 to June 2004, 506 patients underwent contrast MSCTA using a 16-slice CTA. Non-Calcified plaque (NCP) was defined as intraluminal density with 25 ≤ HU ≤ 130. 124 patients (25%) had coronary artery calcium scores of zero and complete conventional risk factor profiles. Of these, 111 patients were followed clinically for a mean of 34 months. Results: The CAC was zero in 124/506 (25%). Of these, 55/124 (44%) had no NCP, 63/124 (51%) had NCP but no significant stenosis, and 6/124 (5%) had NCP and stenosis by MSCTA. Patients in each group were similar in age, but differed significantly in their number of risk factors (Table 1 ). Current or former smokers were more prevalent in the group with stenosis and NCP (83.3%) compared with the other two groups (41.3%, 16.4%), p=0.023. Cardiac events at mean 34 month follow-up: No Plaque: No events NCP but no stenosis : 2/54 (4%) with events (1 sudden cardiac death, 1 VT). NCP with significant stenosis : 2/ 5( 40%) pts had revascularization (1CABG, 1 PCI). Conclusions: Patients with NCP identified with MSCT had significantly more risk factors, especially smoking. NCP without calcium can result in a significant coronary stenosis NCP detected by MSCT in pts with a CAC of 0 identified patients with late cardiac events.

scholarly journals Clinical outcome and hemodynamic performance of St. Jude Trifecta aortic prosthesis: short-term follow-up and risk factors analysis

2019 ◽  
Vol 11 (4) ◽  
pp. 1465-1474 ◽  
Author(s):  
Paolo Nardi ◽  
Calogera Pisano ◽  
Fabio Bertoldo ◽  
Sara Rita Vacirca ◽  
Monica Greci ◽  
...  
Keyword(s):  
Risk Factors ◽  
Clinical Outcome ◽  
Short Term ◽  
Aortic Prosthesis ◽  
Factors Analysis ◽  
Hemodynamic Performance

scholarly journals Clinical outcome and risk factor predictive for failure of autologous PRP injections for low-to-moderate knee osteoarthritis

2021 ◽  
Vol 29 (2) ◽  
pp. 230949902110219
Author(s):  
Mattia Alessio-Mazzola ◽  
Stefano Lovisolo ◽  
Beatrice Sonzogni ◽  
Andrea Giorgio Capello ◽  
Ilaria Repetto ◽  
...  
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Clinical Outcome ◽  
Knee Osteoarthritis ◽  
Significant Risk ◽  
Lower Grade ◽  
Knee Oa ◽  
Significant Independent Risk Factor ◽  
Grade 3

Purpose: To report the 5-year clinical efficacy of PRP intra articular injections in knee osteoarthritis (OA) and to investigate the risk factors predictive for treatment failure and poor clinical outcome. Methods: We retrospectively evaluated 118 patients treated for low to moderate knee OA demonstrated by X-Ray and magnetic resonance imaging (MRI) with autologous PRP injection from 2014 to 2018 with a mean 51.1 ± 14.8 (range 29 to 89) months follow-up. All the patients were evaluated with Lysholm and WOMAC score. The role of Kellgren Lawrence (KL) grade, patello-femoral (PF) degeneration, age, body mass index (BMI), relevant comorbilities, smoking status, gender, previous surgery or conservative measures were analyzed with univariate and multivariate analysis. Results: There was a significant improvement of all outcome measures at final follow-up and high satisfaction rate (79.7%). The overall failure rate was of 15.3% after a mean of 57.7 ± 15.1 (range 33 to 85) months. The BMI and the KL grade were identified as significant independent risk factor related to failure of autologous PRP injection. Patients under 60 reported significantly higher Tegner activity scale ( p = 0.032) at final follow-up. Patients with KL grade 3 and patients with PF MRI-KL grade 3 had significantly lower Lysholm scores ( p = 0.026 and p = 0.042 respectively) at final assessment. Younger patients with lower BMI and lower grade of radiographic OA had significantly longer therapeutic benefit ( p < 0.05). Conclusion: Intra articular PRP injections led to a significant clinical improvement in middle-aged adults with a low to moderate knee OA. BMI and high KL grade have been identified as significant risk factors predictive for failure at mid-term follow-up.

scholarly journals Clinical and Angiographic Outcome of Endovascular and Conservative Treatment for Giant Cavernous Carotid Artery Aneurysms

2014 ◽  
Vol 20 (1) ◽  
pp. 29-36 ◽  
Author(s):  
Zhenhai Zhang ◽  
Xianli Lv ◽  
Zhongxue Wu ◽  
Youxiang Li ◽  
Xinjian Yang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Carotid Artery ◽  
Conservative Treatment ◽  
Clinical Outcome ◽  
Balloon Occlusion ◽  
Parent Artery ◽  
Poor Clinical Outcome ◽  
Parent Artery Occlusion ◽  
Cavernous Carotid Artery

This study evaluated the outcome of endovascular and conservative treatment for giant cavernous carotid artery aneurysms (CCAAs). We retrospectively reviewed a series of 35 consecutive giant CCAAs treated with endovascular and conservative treatment. All patients were evaluated by balloon occlusion test (BOT) before treatment. Patients who could tolerate BOT were treated by parent artery occlusion (PAO), those who could not tolerate BOT were treated by stent/coil or conservative methods. Eight patients were treated conservatively, symptoms were worsened in four patients (50%), unchanged in three, and improved in one at 33.6±19.9 months (6∼65 months) follow-up. In 27 aneurysms treated with endovascular methods, 17 aneurysms were treated by PAO, eight aneurysms were treated with stent-assisted coil embolization, and two aneurysms were embolized with coils. The initial post-procedure angiogram revealed complete occlusion, neck remnant, and incomplete occlusion in 81.5%, 11.1%, and 7.4%, respectively. Procedure-related mortality and morbidity were 0 and 7.4%, respectively. At 33.1±17.4 months (4∼71 months) follow-up, a good clinical outcome (mRS 0–1) was observed in 25 (92.6%) patients, symptoms were resolved or improved in 20 (74.1%). Statistical analysis showed that risk factors for poor clinical outcome included age of 60 years and older (P=0.006), and conservative treatments (P=0.038). Risk factors for poor clinical outcome of giant CCAAs included conservative treatment and age older than 60 years. A symptomatic giant cavernous carotid aneurysm should be treated. The outcome of endovascular treatment of giant CCAAs is promising.

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