The China Stroke Secondary Prevention Trial (CSSPT) Protocol: A Double-Blinded, Randomized, Controlled Trial of Combined Folic Acid and B Vitamins for Secondary Prevention of Stroke

2013 ◽  
Vol 10 (2) ◽  
pp. 264-268 ◽  
Author(s):  
Xuedong Liu ◽  
Ming Shi ◽  
Feng Xia ◽  
Junliang Han ◽  
Zhirong Liu ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Folic Acid ◽  
Secondary Prevention ◽  
Controlled Trial ◽  
B Vitamins ◽  
Prevention Trial ◽  
Secondary Prevention Trial ◽  
Randomized Controlled ◽  
Double Blinded

scholarly journals Effect of Homocysteine-Lowering Treatment With Folic Acid and B Vitamins on Risk of Type 2 Diabetes in Women: A Randomized, Controlled Trial

Diabetes ◽  
2009 ◽  
Vol 58 (8) ◽  
pp. 1921-1928 ◽  
Author(s):  
Y. Song ◽  
N. R. Cook ◽  
C. M. Albert ◽  
M. Van Denburgh ◽  
J. E. Manson
Keyword(s):  
Type 2 Diabetes ◽  
Randomized Controlled Trial ◽  
Folic Acid ◽  
Controlled Trial ◽  
B Vitamins ◽  
Randomized Controlled

scholarly journals Boxing vs Sensory Exercise for Parkinson’s Disease: A Double-Blinded Randomized Controlled Trial

2021 ◽  
pp. 154596832110231
Author(s):  
Kishoree Sangarapillai ◽  
Benjamin M. Norman ◽  
Quincy J. Almeida
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Randomized Controlled Trial ◽  
Repeated Measures ◽  
Rating Scale ◽  
Controlled Trial ◽  
Motor Symptoms ◽  
Post Intervention ◽  
Randomized Controlled ◽  
Double Blinded

Background. Exercise is increasingly becoming recognized as an important adjunct to medications in the clinical management of Parkinson’s disease (PD). Boxing and sensory exercise have shown immediate benefits, but whether they continue beyond program completion is unknown. This study aimed to investigate the effects of boxing and sensory training on motor symptoms of PD, and whether these benefits remain upon completion of the intervention. Methods. In this 20-week double-blinded randomized controlled trial, 40 participants with idiopathic PD were randomized into 2 treatment groups, (n = 20) boxing or (n = 20) sensory exercise. Participants completed 10 weeks of intervention. Motor symptoms were assessed at (week 0, 10, and 20) using the Unified Parkinson’s Disease Rating Scale (UPDRS-III). Data were analyzed using SPSS, and repeated-measures ANOVA was conducted. Results. A significant interaction effect between groups and time were observed F(1, 39) = 4.566, P = .036, where the sensory group improved in comparison to the boxing group. Post hoc analysis revealed that in comparison to boxing, the effects of exercise did not wear off at washout (week 20) P < .006. Conclusion. Future rehabilitation research should incorporate similar measures to explore whether effects of exercise wear off post intervention.

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