Stroke Incidence and 30-Day and Six-Month Case Fatality Rates in Udine, Italy: A Population-Based Prospective Study

2013 ◽  
Vol 8 (SA100) ◽  
pp. 100-105 ◽  
Author(s):  
Francesco Janes ◽  
Gian Luigi Gigli ◽  
Lucio D'Anna ◽  
Iacopo Cancelli ◽  
Anna Perelli ◽  
...  
2019 ◽  
Vol 48 (3-6) ◽  
pp. 149-156 ◽  
Author(s):  
Peter Appelros

Background and Purpose: A stroke incidence study in ­Örebro, situated in Southern Sweden, that was carried out in 1999 showed high incidence rates. Since then, in many Western countries, declining incidence rates have been observed. The main purpose of this study is to examine whether there have been any changes in stroke incidence in the city of ­Örebro between 1999 and 2017. Secondary purposes are to show trends in stroke severity, length of stay and case fatality (CF). Methods: The criterion of an “ideal” stroke incidence study was used in both the 1999 and the present investigation. These criteria include uniform diagnostics, case ascertainment including strokes managed outside the hospital, and the use of several overlapping sources, prospective design, well-defined denominator, and a large population. Results: The overall stroke incidence rate of first ever stroke (adjusted to the 2013 European population) dropped from 346/100,000 (95% CI 314–380) to 168/100,000 (95% CI 148–190). Stroke severity declined from a median of 6 to 4 points on the National Institute of Health Stroke scale. CF within 28 days also declined from 19 to 16% (n.s.). Median length-of-stay in hospital was 16 days in 1999, and 10 days in 2017. Twenty-one per cent of all kinds of stroke were recurrent (not included in the above results). Conclusions: During the years between 1999 and 2017, there have been reductions in stroke incidence, severity and mortality. The explanation is most likely to be found in the prevalence of risk factors and how they are treated. The use of antihypertensives and statins has increased, corresponding to lower levels of blood pressure and cholesterol in the population. The use of anticoagulants in patients with atrial fibrillation has increased. Cigarette smoking has decreased. These are encouraging results that show that preventive medication and public health measures work in practice.


2009 ◽  
Vol 8 (4) ◽  
pp. 355-369 ◽  
Author(s):  
Valery L Feigin ◽  
Carlene MM Lawes ◽  
Derrick A Bennett ◽  
Suzanne L Barker-Collo ◽  
Varsha Parag

Stroke ◽  
2015 ◽  
Vol 46 (5) ◽  
pp. 1173-1179 ◽  
Author(s):  
Anne Merete Vangen-Lønne ◽  
Tom Wilsgaard ◽  
Stein Harald Johnsen ◽  
Maria Carlsson ◽  
Ellisiv B. Mathiesen

Background and Purpose— Ischemic stroke incidence has declined in industrialized countries the last decades, with possible exception for the youngest age groups. We estimated age- and sex-specific trends in incidence and case fatality of first-ever ischemic stroke between 1977 and 2010 in a Norwegian municipality. Methods— Age-adjusted time trends in incidence from 1977 to 2010 were estimated by fractional polynomial and Poisson regression, and case fatality by logistic regression in 36 575 participants of the population-based Tromsø Study. Results— There were 1214 first-ever ischemic strokes within a total follow-up time of 611 176 person-years. The overall age- and sex-adjusted incidence decreased by 24% in 1995 to 2010. In women aged 30 to 49 years, the incidence increased significantly from 1980 to 2010. In men aged 30 to 49 years, there was a nonsignificant, rising trend from 1977 to 2010. Men aged 50 to 64 years had similar incidence in 2010 compared with 1989. From the mid-1990s to 2010, the incidence declined significantly in women aged 50 to 74 years and in men aged 65 to 74 years, but remained stable in those aged ≥75 years. Case fatality decreased significantly in men aged 30 to 84 years from 1995 to 2010, whereas there was no significant change in women. Conclusions— Age-adjusted incidence of first-ever ischemic stroke increased in young women, declined in women aged 50 to 74 years and men aged 65 to 74 years and remained stable among the oldest. Case fatality declined in men aged 30 to 84 years, but not in women.


2021 ◽  
pp. 174749302199559
Author(s):  
Eleni Karantali ◽  
Konstantinos Vemmos ◽  
Evangelos Tsampalas ◽  
Konstantinos Xynos ◽  
Persefoni Karachalia ◽  
...  

Background Stroke incidence and case-fatality are reported to decline in high-income countries during the last decades. Epidemiological studies are important for health services to organize prevention and treatment strategies. Aims The aim of this population-based study was to determine temporal trends of stroke incidence and case-fatality rates of first-ever stroke in Arcadia, a prefecture in southern Greece. Methods All first-ever stroke cases in the Arcadia prefecture were ascertained using the same standard criteria and multiple overlapping sources in three study periods: from November 1993 to October 1995; 2004; and 2015–2016. Crude and age-adjusted to European population incidence rates were compared using Poisson regression. Twenty-eight days case fatality rates were estimated and compared using the same method. Results In total, 1315 patients with first-ever stroke were identified. The age-standardized incidence to the European population was 252 per 100,000 person-years (95% CI 231–239) in 1993/1995, 252 (95% CI 223–286) in 2004, and 211 (192–232) in 2015/2016. The overall age- and sex-adjusted incidence rates fell by 16% (incidence rates ratio 0.84, 95% CI: 0.72–0.97). Similarly, 28-day case-fatality rate decreased by 28% (case fatality rate ratio = 0.72, 95% CI: 0.58–0.90). Conclusions This population-based study reports a significant decline in stroke incidence and mortality rates in southern Greece between 1993 and 2016.


Stroke ◽  
2015 ◽  
Vol 46 (suppl_1) ◽  
Author(s):  
Jane C Khoury ◽  
Samrat Yeramaneni ◽  
J. Michael Taylor ◽  
Laura Lehman ◽  
Heidi Sucharew ◽  
...  

Background: We have published rates of childhood stroke using our population-based Greater Cincinnati Northern Kentucky Stroke Study for 1993/4 and 1999. We now report population-based rates from additional study periods of 2005 and 2010, and compare rates over time periods. Methods: We identified all strokes in the Greater Cincinnati/Northern Kentucky (GCNK) region, a biracial population of 1.3 million, during 7/1/93 to 6/30/94 and calendar years 1999, 2005 and 2010. Stroke cases (both hemorrhagic and ischemic) were ascertained by screening for discharge ICD-9 codes 430 - 436 at all local hospitals, 437 - 438, 674 and 747 were also screened at the Children’s Hospital. Childhood stroke is defined as stroke in those <20 years of age at the time of onset. Incidence and overall stroke rates are estimated per 100,000, age-, sex- and race-adjusted to the 2000 US population. Results: There were 14 strokes in children in 1993/4, 24 strokes in 1999, 15 strokes in 2005 and 17 strokes in 2010. Incidence rates by study period, overall, by race, sex and stroke type are reported in the table. We do not detect any significant change in the incidence rate over time. The overall (first ever or recurrent) stroke rate age-, sex- and race-adjusted to the 2000 US population under 20 years of age for the entire study period, is 4.4/100,000 (95% confidence interval: 3.4, 5.4),. Eleven children died within 30 days yielding an all-cause case fatality rate of 16%. Among all childhood stroke cases, 9 (13%) were identified at hospitals other than the Children’s Hospital. Conclusions: The childhood stroke incidence rate of 4.1 per 100,000, in the GCNK study region has not changed significantly over 17 years Any study of pediatric stroke incidence should include screening of non-pediatric hospitals, as we found 13% of cases in adult hospitals.


Stroke ◽  
1994 ◽  
Vol 25 (3) ◽  
pp. 552-557 ◽  
Author(s):  
R Bonita ◽  
C S Anderson ◽  
J B Broad ◽  
K D Jamrozik ◽  
E G Stewart-Wynne ◽  
...  

Author(s):  
Valentina Arnao ◽  
Giuseppe Salemi ◽  
Salvatore Scondotto ◽  
Nicola Casuccio ◽  
Marianna Riolo ◽  
...  

Abstract Background The incidence of stroke in high-income countries has been on the decline; however, few epidemiological surveys have been conducted in recent years to specifically estimate the incidence along with outcome of stroke, in Italy. This study aimed to examine the incidence and case fatality rates of stroke in an elderly Italian population. Methods A cohort of 2200 people > 65 years was randomly stratified from the total elderly population of Bagheria, Italy. A 9-year prospective population-based study was performed (19,800 person/years). Results We identified 112 first-ever strokes, 53 females and 59 males: 82 (73.1%) ischemic, 13(11.6%) intracerebral haemorrhages, 6 (5.35%) subarachnoid haemorrhages, while 11(9.8%) were classified as undetermined strokes. The crude overall annual incidence was 5.65 per 1000 (95%CI: 4.61 to 6.70) for first-ever stroke. The overall crude incidence rates were 4.74 per 1000 (5.08 for males and 4.46 for females) for ischemic stroke, 0.65 (0.99 for males and 0.37 for females) for intracerebral haemorrhage, and 0.03 for subarachnoid haemorrhage. The incidence rate for first-ever stroke was 5.4 per 1000 (95% CI: 5.36 to 5.45) after adjustment for the 2015 World population and 5.56 (95% CI: 5.52 to 5.61), compared to the 2015 European population. Overall case fatality rates for first-ever stroke was 8.19% at 28 days and 24.1% at 1 year. Conclusion Our study shows that in the elderly population investigated, stroke incidence and case fatality rates resulted being lower, compared to those from Italian and most European populations. Similar to previous studies, these rates increased linearly with age and were higher in males.


2015 ◽  
Vol 10 (SA100) ◽  
pp. 96-102 ◽  
Author(s):  
Ali Shoeibi ◽  
Maryam Salehi ◽  
Amanda G. Thrift ◽  
Moira K. Kapral ◽  
Mohammad Taghi Farzadfard ◽  
...  

2020 ◽  
Vol 54 (6) ◽  
pp. 454-461
Author(s):  
Prashant Mathur ◽  
Sukanya Rangamani ◽  
Vaitheeswaran Kulothungan ◽  
Deepadarshan Huliyappa ◽  
Bhoomika Bajaj Bhalla ◽  
...  

The burden of stroke is increasing, and India lacks comparable long-term data on stroke incidence and mortality. Disease surveillance using a registry model can provide long-term data on stroke for linking with public health interventions in stroke prevention, treatment, and rehabilitation. The objectives of the National Stroke Registry Programme (NSRP), India, are to generate reliable data on the incidence of first-ever stroke events in defined populations through a population-based stroke registry (PBSR) and to describe the patterns of care and outcomes of patients with stroke in different treatment settings through a hospital-based stroke registry (HBSR). Continuous systematic collection on a standardized format of diagnostic, treatment, and outcome information on stroke events in persons of defined population (PBSR) and those who attend hospitals (HBSR) is conducted through active data abstraction from review of records from all health facilities and imaging centres that cater to stroke patients. Data are ICD coded, verified, and completed by obtaining survival status of registered patients. IT tools are used for data collection,management and analysis. The NSRP shall establish a standardized stroke surveillance system that would reliably measure stroke incidence, subtypes, treatment patterns, complications, disability, case fatality, and survival. This evidence shall inform health planning of stroke interventions and control activities. It would facilitate improvement in stroke services to improve quality of care and outcomes of stroke. A thrust for research on stroke would be encouraged based on evidence-based hypothesis generation.


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