Chromosome 16 changes do not always come for good

2021 ◽  
Author(s):  
Ambra Paolini ◽  
Vincenzo Nasillo ◽  
Beatrice Lusenti ◽  
Luca Roncati ◽  
Enrico Tagliafico ◽  
...  
Keyword(s):  
Chromosome 16

Congenic strains confirm aerobic running capacity quantitative trait loci on rat chromosome 16 and identify possible intermediate phenotypes

2007 ◽  
Vol 29 (1) ◽  
pp. 91-97 ◽  
Author(s):  
Justin A. Ways ◽  
Brian M. Smith ◽  
John C. Barbato ◽  
Ramona S. Ramdath ◽  
Krista M. Pettee ◽  
...  
Keyword(s):  
Quantitative Trait Loci ◽  
Quantitative Trait ◽  
Strain Differences ◽  
Proximal Portion ◽  
Chromosome 16 ◽  
Rat Strains ◽  
High Performing ◽  
Intermediate Phenotypes ◽  
Trait Loci ◽  
Inbred Rat

We previously identified two inbred rat strains divergent for treadmill aerobic running capacity (ARC), the low-performing Copenhagen (COP) and the high-performing DA rats, and used an F2(COP×DA) population to identify ARC quantitative trait loci (QTLs) on rat chromosome 16 (RNO16) and the proximal portion of rat chromosome 3 (RNO3). Two congenic rat strains were bred to further investigate these ARC QTLs by introgressing RNO16 and the proximal portion of RNO3 from DA rats into the genetic background of COP rats and were named COP.DA(chr 16) and COP.DA(chr 3), respectively. COP.DA(chr 16) rats had significantly greater ARC compared with COP rats (696.7 ± 38.2 m vs. 571.9 ± 27.5 m, P = 0.03). COP.DA(chr 3) rats had increased, although not significant, ARC compared with COP rats (643.6 ± 40.9 m vs. 571.9 ± 27.5 m). COP.DA(chr 16) rats had significantly greater subcutaneous abdominal fat, as well as decreased fasting triglyceride levels, compared with COP rats ( P < 0.05), indicating that genes responsible for strain differences in fat metabolism are also located on RNO16. While this colocalization of QTLs may be coincidental, it is also possible that these differences in energy balance may be associated with the superior running performance of COP.DA(chr 16) consomic rats.

The FRA16D common chromosomal fragile site co-localizes with a region of LOH on chromosome 16 in hepatocellular carcinoma

2001 ◽  
Vol 120 (5) ◽  
pp. A360-A361
Author(s):  
Ileana Aderca ◽  
Damian P. Montoya ◽  
Kurt A. Krummel ◽  
David M. Nagorney ◽  
David I. Smith ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Fragile Site ◽  
Chromosome 16

The fragile site on chromosome 16 (q21q22)

1980 ◽  
Vol 55 (1) ◽  
pp. 19-22 ◽  
Author(s):  
F. Shabtai ◽  
S. Bichacho ◽  
I. Halbrecht
Keyword(s):  
Fragile Site ◽  
Chromosome 16

A constitutional bws-related t(11;16) chromosome translocation occurring in the same region of chromosome 16 implicated in wilms' tumors

1995 ◽  
Vol 12 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Irene Newsham ◽  
Andrea Kindler-Röhrborn ◽  
Douglas Daub ◽  
Webster Cavenee
Keyword(s):  
Chromosome Translocation ◽  
Chromosome 16

scholarly journals Isolation and mapping of a polymorphic DNA sequence (pCJ52.209M1) on chromosome 16 [D16S151]

1989 ◽  
Vol 17 (18) ◽  
pp. 7542-7542
Author(s):  
C. Julier ◽  
Y. Nakamura ◽  
G. M. Lathrop ◽  
J.-M. Lalouel ◽  
R. White
Keyword(s):  
Dna Sequence ◽  
Chromosome 16

Localization of the active gene of aldolase on chromosome 16, and two aldolase A pseudogenes on chromosomes 3 and 10

1988 ◽  
Vol 78 (2) ◽  
pp. 167-174 ◽  
Author(s):  
S. Serero ◽  
P. Maire ◽  
Nguyen Van Cong ◽  
O. Cohen-Haguenauer ◽  
M. S. Gross ◽  
...  
Keyword(s):  
Chromosome 16 ◽  
Active Gene ◽  
Aldolase A
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