Sodium citrate blood contamination by K2-ethylenediaminetetraacetic acid (EDTA): impact on routine coagulation testing

2014 ◽  
Vol 37 (3) ◽  
pp. 403-409 ◽  
Author(s):  
G. Lima-Oliveira ◽  
G. L. Salvagno ◽  
E. Danese ◽  
E. J. Favaloro ◽  
G. C. Guidi ◽  
...  
Keyword(s):  
Sodium Citrate ◽  
Ethylenediaminetetraacetic Acid ◽  
Blood Contamination ◽  
Coagulation Testing ◽  
Citrate Blood ◽  
Routine Coagulation

Comparison of the influence of EDTA-K3 and sodium citrate on haematology analysis in healthy dogs

2012 ◽  
Vol 15 (2) ◽  
pp. 391-392 ◽  
Author(s):  
M. Żmigrodzka ◽  
A. Winnicka ◽  
M. Guzera
Keyword(s):  
Platelet Count ◽  
Sodium Citrate ◽  
Ethylenediaminetetraacetic Acid ◽  
Haemoglobin Concentration ◽  
Healthy Dogs ◽  
Citrate Blood

Comparison of the influence of EDTA-K3 and sodium citrate on haematology analysis in healthy dogs The study was carried out on 30 clinically healthy dogs of various breeds. Haemoglobin concentration, haematocrit, platelet count and platelet haematocrit were significantly lower in citrate blood than in tripotassium ethylenediaminetetraacetic acid (EDTA-K3) blood. The study confirmed the limited usage of sodium citrate in haematology analysis, unless canine EDTA-dependent thrombocytopenia is suspected.

scholarly journals Effect of 3.2%vs3.8% Sodium Citrate Concentration on Routine Coagulation Testing

1997 ◽  
Vol 107 (1) ◽  
pp. 105-110 ◽  
Author(s):  
Dorothy M. Adcock ◽  
David C. Kressin ◽  
Richard A. Marlar
Keyword(s):  
Sodium Citrate ◽  
Citrate Concentration ◽  
Coagulation Testing ◽  
Routine Coagulation

EDTA‑dependent pseudothrombocytopenia in child (clinical case report)

2021 ◽  
pp. 51-54
Author(s):  
N. A. Sokolova ◽  
M. I. Savina ◽  
O. S. Shokhina
Keyword(s):  
Platelet Count ◽  
Clinical Case ◽  
Sodium Citrate ◽  
Ethylenediaminetetraacetic Acid ◽  
Hemorrhagic Diathesis ◽  
Platelet Dysfunction ◽  
Rare Presentation ◽  
Blood Samples ◽  
Low Platelet Count ◽  
Aggregation Of Platelets

Ethylenediaminetetraacetic acid (EDTA)-dependent pseudothrombocytopenia is the phenomenon of a spurious low platelet count due to antiplatelet antibodies that cause platelet clumping in blood anticoagulated with EDTA. The aggregation of platelets in EDTA-dependent pseudothrombocytopenia is usually prevented by other anticoagulants, such as sodium citrate. EDTA-dependent pseudothrombocytopenia has never been associated with hemorrhagic diathesis or platelet dysfunction. In this article, a 2,5-year-old boy with EDTA-dependent pseudothrombocytopenia is presented because of rare presentation. We report that EDTA can induce platelet clumping, and thus spuriously low platelet counts. However, aggregation of platelets was not detected in blood samples with sodium citrate, and platelet count was normal.

scholarly journals Influence of Centrifuge Temperature on Routine Coagulation Testing

2006 ◽  
Vol 52 (3) ◽  
pp. 537-538 ◽  
Author(s):  
Giuseppe Lippi ◽  
Gian Luca Salvagno ◽  
Martina Montagnana ◽  
Giovanni Poli ◽  
Gian Cesare Guidi
Keyword(s):  
Coagulation Testing ◽  
Routine Coagulation

Minimum citrate tube fill volume for routine coagulation testing

2013 ◽  
Vol 36 (4) ◽  
pp. 493-495 ◽  
Author(s):  
L. Pretorius ◽  
W. J. Janse van Rensburg ◽  
C. Conradie ◽  
M. J. Coetzee
Keyword(s):  
Coagulation Testing ◽  
Fill Volume ◽  
Routine Coagulation

Polymicrobial pseudobacteraemias associated with non-sterile sodium citrate blood collection tubes

1993 ◽  
Vol 25 (4) ◽  
pp. 297-299 ◽  
Author(s):  
P.G. Rathbone ◽  
V. Sinickas ◽  
V. Humphery ◽  
S. Graves ◽  
A. Hellyar
Keyword(s):  
Sodium Citrate ◽  
Blood Collection ◽  
Blood Collection Tubes ◽  
Citrate Blood

scholarly journals Preanalytical Variables in Coagulation Testing: Setting the Stage for Accurate Results

2019 ◽  
Vol 45 (05) ◽  
pp. 433-448 ◽  
Author(s):  
Robert C. Gosselin ◽  
Richard A. Marlar
Keyword(s):  
Laboratory Practice ◽  
Coagulation Assays ◽  
Practice Recommendations ◽  
Specimen Collection ◽  
Coagulation Testing ◽  
Specimen Processing ◽  
Processing And Storage ◽  
And Storage ◽  
Routine Coagulation

AbstractMany preanalytical variables may affect the results of routine coagulation assays. While advances in laboratory instrumentation have partially addressed the laboratory's ability to recognize some of these variables, there remains an increased reliance on laboratory personnel to recognize the three potential areas where coagulation testing preanalytical issues may arise: (1) specimen collection (including patient selection), (2) specimen transportation and stability, and (3) specimen processing and storage. The purpose of this article is to identify the preanalytical variables associated with coagulation-related testing and provide laboratory practice recommendations in an effort to improve the quality of coagulation testing and accuracy of result reporting.

Validation of a New Small-Volume Sodium Citrate Collection Tube for Coagulation Testing in Critically Ill Patients with Coagulopathy

2018 ◽  
Vol 64 (06/2018) ◽  
Author(s):  
Elisabeth Adam ◽  
Kai Zacharowski ◽  
Gudrun Hintereder ◽  
Florian Raimann ◽  
Patrick Meybohm
Keyword(s):  
Critically Ill ◽  
Critically Ill Patients ◽  
Sodium Citrate ◽  
Small Volume ◽  
Coagulation Testing ◽  
Collection Tube
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