Characteristic tryptic peptides and gelling properties of porcine skin gelatin affected by thermal action

2021 ◽  
Author(s):  
Xiao‐Mei Sha ◽  
Li‐Jun Zhang ◽  
Wen‐Mei Chen ◽  
Guang‐Yao Wang ◽  
Jin‐Lin Li ◽  
...  
Keyword(s):  
Thermal Action ◽  
Porcine Skin ◽  
Tryptic Peptides ◽  
Gelling Properties

THERMAL ACTION OF MICROWAVE RADIATION ON A VERY THIN CONDUCTIVE FIBER

2018 ◽  
Vol 77 (19) ◽  
pp. 1719-1727
Author(s):  
N. G. Kokodiy ◽  
М. V. Kaydash ◽  
S. V. Pogorelov
Keyword(s):  
Microwave Radiation ◽  
Thermal Action ◽  
Conductive Fiber

Acellular porcine skin and allogeneic skin as wound-covering materials for extensive deep burns:a comparative study

2013 ◽  
Vol 32 (11) ◽  
pp. 1207-1211
Author(s):  
Wu-quan LI ◽  
Xiao-chen QIU ◽  
Jun LIU ◽  
Di-nan WEI ◽  
Zong-hua CHEN ◽  
...  
Keyword(s):  
Comparative Study ◽  
Porcine Skin

Simulation of volumetric heating of a moist medium with allowance for fluid mobility

2012 ◽  
Vol 9 (1) ◽  
pp. 91-93
Author(s):  
U.R. Ilyasov ◽  
A.V. Dolgushev
Keyword(s):  
Mass Transfer ◽  
Porous Medium ◽  
Numerical Solution ◽  
Heat And Mass Transfer ◽  
Transfer Process ◽  
Thermal Action ◽  
Mass Transfer Process ◽  
Low Permeability ◽  
Volumetric Heating ◽  
Drying Regime

The problem of volumetric thermal action on a moist porous medium is considered. Numerical solution, the influence of fluid mobility on the dynamics of the heat and mass transfer process is analyzed. It is established that fluid mobility leads to a softer drying regime. It is shown that in low-permeability media, the fluid can be assumed to be stationary.

Microneedle-Assisted Percutaneous Transport of Magnesium Sulfate

2020 ◽  
Vol 17 (2) ◽  
pp. 140-147
Author(s):  
Karna B. Ghimirey ◽  
Kevin Ita
Keyword(s):  
Confocal Microscopy ◽  
Stratum Corneum ◽  
Magnesium Sulfate ◽  
Inductively Coupled Plasma ◽  
Optical Emission ◽  
Magnesium Concentration ◽  
Porcine Skin ◽  
Time Curve ◽  
Student’S T

Objective: In vitro diffusion experiments were performed to assess the permeation of magnesium sulfate across pig skin. Method: The mean thickness of the dermatomed porcine skin was 648 ± 12 µm. Magnesium concentration was measured using inductively coupled plasma-optical emission spectroscopy. Transdermal flux of magnesium sulfate across MN-treated and untreated porcine skin was obtained from the slope of the steady-state linear portion of cumulative amount versus time curve. Results: Statistical analysis of the results was done with Student’s t-test. The transdermal flux of magnesium sulfate across microneedle-treated porcine skin was 134.19 ± 2.4 µg/cm2/h and transdermal flux across untreated porcine skin was 4.64 ± 0.05 µg/cm2/h. Confocal microscopy was used to visualize the microchannels created by a solid microneedle roller (500 µm). Conclusion: From our confocal microscopy studies, it was evident that the 500 μm long microneedles disrupted the stratum corneum and created microchannels measuring 191 ± 37 µm. The increase in transdermal flux across the microneedle-treated skin was statistically significant compared to that of controls, i.e., without the application of microneedles. With the application of microneedles, the transdermal flux of magnesium permeated over 12 h was approximately 33-fold higher in comparison to passive diffusion across an intact stratum corneum.

C-Terminal amino acid sequence of chicken pepsinogen and its homology with sequences of other acid proteases

1980 ◽  
Vol 45 (4) ◽  
pp. 1144-1154 ◽  
Author(s):  
Miroslav Baudyš ◽  
Helena Keilová ◽  
Vladimír Kostka
Keyword(s):  
Amino Acid ◽  
Amino Acid Sequence ◽  
The Other ◽  
Terminal Sequence ◽  
Terminal Part ◽  
Terminal Amino Acid ◽  
Tryptic Peptides ◽  
Terminal Amino ◽  
High Degree ◽  
Terminal Amino Acid Sequence

To determine the primary structure of the C-terminal part of the molecule of chicken pepsinogen the tryptic, chymotryptic and thermolytic digest of the protein were investigated and peptides derived from this region were sought. These peptides permitted the following 21-residue C-terminal sequence to be determined: ...Ile-Arg-Glu-Tyr-Tyr-Val-Ile-Phe-Asp-Arg-Ala-Asn-Asn-Lys-Val-Gly-Leu-Ser-Pro-Leu-Ser.COOH. A comparison of this structure with the C-terminal sequential regions of the other acid proteases shows a high degree of homology between chicken pepsinogen and these proteases (e.g., the degree of homology with respect to hog pepsinogen and calf prochymosin is about 66%). Additional tryptic peptides, derived from the N-terminal part of the zymogen molecule whose amino acid sequence has been reported before, were also obtained in this study. This sequence was extended by two residues using an overlapping peptide. An ancillary result of this study was the isolation of tryptic peptides derived from other regions of the zymogen molecule.

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