scholarly journals A new application for the valorization of pomegranate seed oil: nanoencapsulation of pomegranate seed oil into electrospun nanomats for food preservation

2021 ◽  
Author(s):  
Nazan Kutlu ◽  
Raciye Meral ◽  
Mehmet Mustafa Ekin ◽  
Yagmur Erim Kose ◽  
Zafer Ceylan
Keyword(s):  
Seed Oil ◽  
Food Preservation ◽  
Pomegranate Seed Oil ◽  
Pomegranate Seed

In Vitro Estimation of Photo-Protective Potential of Pomegranate Seed Oil and Development of a Nanoformulation

2019 ◽  
Vol 15 (1) ◽  
pp. 87-102 ◽  
Author(s):  
Surbhi Dhawan ◽  
Sanju Nanda
Keyword(s):  
Particle Size ◽  
Zeta Potential ◽  
Seed Oil ◽  
Topical Delivery ◽  
Inflammatory Activity ◽  
Pomegranate Seed Oil ◽  
Protective Potential ◽  
Release Studies ◽  
Pomegranate Seed

Background: Since ancient times, people have been using natural resources for photoprotection purposes. One such highly recognised natural agent is pomegranate seed oil, considered as wonder oil owing to the presence of several beneficial phytoconstituents. </P><P> Objective: The study aimed to establish the photoprotective potential of pomegranate seed oil through various in vitro and biochemical studies along with the formation of nanoemulsion, an efficient topical delivery system for the oil. </P><P> Method: Photo-protective potential of the oil was estimated by determining in vitro antioxidant and anti-inflammatory activity, total phenolic content, anti elastase, antihyaluronidase and anticollagenase activities of the oil. Ultrasonication method was used to formulate nanoemulsions. The optimisation was done following the central composite design. The characterisation was done by particle size analysis, zeta potential, polydispersity index, pH, viscosity, stability testing and transmission electron microscopy. The optimised nanoemulsion was loaded into a gel base for topical application and further release studies were carried out. </P><P> Results: The IC50 values of anti-elastase, anti-collagenase and anti-hyaluronidase were found to be 309 mg/ml, 4 mg/ml and 95 mg/ml respectively. The results of anti-oxidant and anti-inflammatory activity were also significant, which thereby established the photo-protective potential of the oil. The optimum batch 2 had particle size 83.90 nm, 0.237 PDI and -5.37 mV zeta potential. The morphology was confirmed by TEM. Batch 2 was incorporated into a gel base and release studies showed 74.12 % release within 7 hours. </P><P> Conclusion: Pomegranate seed oil possesses a potential photo-protective ability. Nanoemulsions proved to be a promising carrier for the topical delivery of the oil.

Evaluation of green extraction processes, lipid composition and antioxidant activity of pomegranate seed oil

2021 ◽  
Author(s):  
E. Rojo-Gutiérrez ◽  
O. Carrasco-Molinar ◽  
J. M. Tirado-Gallegos ◽  
A. Levario-Gómez ◽  
M. L. Chávez-González ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Lipid Composition ◽  
Seed Oil ◽  
Green Extraction ◽  
Pomegranate Seed Oil ◽  
Extraction Processes ◽  
Pomegranate Seed

Chemopreventive Effects of Pomegranate Seed Oil on Skin Tumor Development in CD1 Mice

2003 ◽  
Vol 6 (3) ◽  
pp. 157-161 ◽  
Author(s):  
Justin J. Hora ◽  
Emily R. Maydew ◽  
Ephraim P. Lansky ◽  
Chandradhar Dwivedi
Keyword(s):  
Seed Oil ◽  
Tumor Development ◽  
Skin Tumor ◽  
Pomegranate Seed Oil ◽  
Cd1 Mice ◽  
Pomegranate Seed

Protective effect of pomegranate seed oil on hexachlorobutadiene-induced nephrotoxicity in rat kidneys

Renal Failure ◽  
2010 ◽  
Vol 32 (5) ◽  
pp. 612-617 ◽  
Author(s):  
Mohammad Taher Bouroshaki ◽  
Hamid Reza Sadeghnia ◽  
Marjan Banihasan ◽  
Samaneh Yavari
Keyword(s):  
Protective Effect ◽  
Seed Oil ◽  
Pomegranate Seed Oil ◽  
Pomegranate Seed ◽  
Rat Kidneys

scholarly journals The Role of Pometone (Pomegranate seed oil) in Ameliorating the Deleterious Effect of Methionine Overload on Some Histological Aspects of heart and aorta in Female Rabbits (Part-II)

2014 ◽  
Vol 38 (1) ◽  
pp. 62-70
Author(s):  
Baraa Najim Al-Okaily
Keyword(s):  
Cardiac Muscle ◽  
Muscle Fiber ◽  
Seed Oil ◽  
Mononuclear Cells ◽  
Corn Oil ◽  
Control Group ◽  
Aortic Tissue ◽  
Pomegranate Seed Oil ◽  
Pomegranate Seed

This experiment was aimed to investigate the role of pomegranate seed oil (PSO) in ameliorating the deleterious effects of methionine overload on some histopathological structure of heart and aorta in adult female rabbits. Thirty-Two female rabbits divided into four groups eight animals each, and treated for 42 days daily as follows: the first groups were drenched drinking corn oil, serving as control (group C), second group (group T1) were intubated orally with methionine 100mg/kg. B.W, while the third group (groupT2) were intubated orally with methionine 100mg/kg. B.W and pomegranate seed oil (PSO) 30 mg /Kg. B.W, and the animals in group T3 were intubated orally with pomegranate seed oil 30 mg /Kg. B.W. At the end of the experiment rabbits were sacrificed. Serial sections from the heart and aorta were prepared and examined microscopically. Histological examination of heart and aorta of methionine overload treated group (T1) showed edema ,RBCs and few neutrophils infiltration ,with vacuolar degeneration of cardiac muscle cells , fragment of muscle fiber, congested blood vessels between muscle fibers. An increase in thickness of intima, erosion and mononuclear cells infiltration in sub intima of aorta were also observed. Histological sections of heart and aorta in T2 and T3 groups showed the absence of histopathological lesions in aortic tissue with moderate edema between muscle fiber of T2 group as comparing to group T1. In conclusion, the results confirm the cardioprotective role of pomegranate seed oil by ameliorating the effect of methionine overload on cardiac muscle and aorta.

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