Acetylcholinesterase-inhibitor hydrolysates obtained from ‘in vitro’ enzymatic hydrolysis of mannoproteins extracted from different strains of yeasts

2015 ◽  
Vol 51 (2) ◽  
pp. 300-308 ◽  
Author(s):  
Pablo G. Spontón ◽  
Roque Spinelli ◽  
Silvina R. Drago ◽  
Georgina G. Tonarelli ◽  
Arturo C. Simonetta
Keyword(s):  
Enzymatic Hydrolysis ◽  
Acetylcholinesterase Inhibitor ◽  
Different Strains ◽  
Hydrolysis Of

scholarly journals Enzymatic Hydrolysis of Copoly (N-hydroxypropyl-L-glutamine/L-alanine) Fibers in vitro.

2000 ◽  
Vol 56 (2) ◽  
pp. 98-103 ◽  
Author(s):  
Kazuyuki Jokei ◽  
Takanori Hayashi ◽  
Masakazu Furuta ◽  
Masahito Oka ◽  
Toshio Hayashi
Keyword(s):  
Enzymatic Hydrolysis ◽  
Hydrolysis Of

scholarly journals Enzymatic Hydrolysis of Pneumococcal Capsular Polysaccharide Renders the Bacterium Vulnerable to Host Defense

2018 ◽  
Vol 86 (8) ◽  
Author(s):  
Dustin R. Middleton ◽  
Amy V. Paschall ◽  
Jeremy A. Duke ◽  
Fikri Y. Avci
Keyword(s):  
Enzymatic Hydrolysis ◽  
Capsular Polysaccharide ◽  
Protective Role ◽  
Pneumococcal Infections ◽  
Content Type ◽  
Drug Resistant Strains ◽  
Type 3 ◽  
Hydrolysis Of

ABSTRACTDespite a century of investigation,Streptococcus pneumoniaeremains a major human pathogen, causing a number of diseases, such as pneumonia, meningitis, and otitis media. Like many encapsulated pathogens, the capsular polysaccharide (CPS) ofS. pneumoniaeis a critical component for colonization and virulence in mammalian hosts. This study aimed to evaluate the protective role of a glycoside hydrolase, Pn3Pase, targeting the CPS of type 3S. pneumoniae, which is one of the most virulent serotypes. We have assessed the ability of Pn3Pase to degrade the capsule on a live type 3 strain. Throughin vitroassays, we observed that Pn3Pase treatment increases the bacterium's susceptibility to phagocytosis by macrophages and complement-mediated killing by neutrophils. We have demonstrated thatin vivoPn3Pase treatment reduces nasopharyngeal colonization and protects mice from sepsis caused by type 3S. pneumoniae. Due to the increasing shifts in serotype distribution, the rise in drug-resistant strains, and poor immune responses to vaccine-included serotypes, it is necessary to investigate approaches to combat pneumococcal infections. This study evaluates the interaction of pneumococcal CPS with the host at molecular, cellular, and systemic levels and offers an alternative therapeutic approach for diseases caused byS. pneumoniaethrough enzymatic hydrolysis of the CPS.

scholarly journals Generation of dipeptidyl peptidase IV (DPP-IV) inhibitory peptides during the enzymatic hydrolysis of tropical banded cricket (Gryllodes sigillatus) proteins

2018 ◽  
Vol 9 (1) ◽  
pp. 407-416 ◽  
Author(s):  
Alice B. Nongonierma ◽  
Candice Lamoureux ◽  
Richard J. FitzGerald
Keyword(s):  
Enzymatic Hydrolysis ◽  
Dipeptidyl Peptidase ◽  
Protein Hydrolysates ◽  
Dipeptidyl Peptidase Iv ◽  
Inhibitory Peptides ◽  
Dpp Iv ◽  
Gryllodes Sigillatus ◽  
Hydrolysis Of

Cricket (Gryllodes sigillatus) protein hydrolysates inhibit dipeptidyl peptidase IV (DPP-IV) in vitro.

In vitro enzymatic hydrolysis of protein and protein pattern change of soya and faba beans during germination

1992 ◽  
Vol 42 (3) ◽  
pp. 275-284 ◽  
Author(s):  
F. H. M. G. Savelkoul ◽  
H. Boer ◽  
S. Tamminga ◽  
A. J. Schepers ◽  
L. Elburg
Keyword(s):  
Enzymatic Hydrolysis ◽  
Protein Pattern ◽  
Pattern Change ◽  
Faba Beans ◽  
Hydrolysis Of

Enzymatic hydrolysis of copoly(N-hydroxypropyl-L-glutamine/L-leucine) hydrogels in vitro

1996 ◽  
Vol 7 (9) ◽  
pp. 805-816 ◽  
Author(s):  
Yasuyoshi Miyachi ◽  
Kazuyuki Joke ◽  
Masahito Oka ◽  
Toshio Hayashi
Keyword(s):  
Enzymatic Hydrolysis ◽  
Hydrolysis Of

scholarly journals Enzymatic Hydrolysis of Multi-Component Random Copolypeptides in Vitro

1993 ◽  
Vol 25 (3) ◽  
pp. 285-290 ◽  
Author(s):  
Yasuko Iizuka ◽  
Masanao Oya ◽  
Makoto Iwatsuki ◽  
Toshio Hayashi
Keyword(s):  
Enzymatic Hydrolysis ◽  
Hydrolysis Of
Sign in / Sign up

Export Citation Format

Share Document