Pustulotic arthro‐osteitis with generalized pustulosis lagging 20 years behind the onset of joint symptoms

2021 ◽  
Author(s):  
Shiho Sunami ◽  
Tetsuya Honda ◽  
Yo Kaku ◽  
Yuichiro Endo ◽  
Alshimaa Mostafa ◽  
...  
Keyword(s):  
Joint Symptoms

HYPEROESTROGENISMUS AND RHEUMATOID ARTHRITIS

1960 ◽  
Vol XXXIV (I) ◽  
pp. 45-50 ◽  
Author(s):  
J. L. Kalliomäki ◽  
Lauri Rauramo
Keyword(s):  
Rheumatoid Arthritis ◽  
Cervical Cancer ◽  
Urine Samples ◽  
Menstrual Bleeding ◽  
Menstrual Phase ◽  
Joint Symptoms ◽  
The Mean

ABSTRACT The authors have endeavoured to clarify the frequency of the hyperoestrogenismus syndrome in women with rheumatoid arthritis, aged 17–38 years, by means of clinical and cytologic studies, and by hormonal analyses. The material comprises 32 patients. Of these, 30 were suitable for cytologic observation. In 5 (17 %) of these 30 patients, the hyperoestrogenismus syndrome (17 %) may be considered definitely established. Aggravation of the joint symptoms in the pre-menstrual phase was reported by 41 % of the patients. Values for excretion of oestrogen exceeding 200 mouse units/24 hours were noted one week before menstrual bleeding in 8 of 19 women; the mean for oestrogen excretion was 268 mouse units/24 hours. Gonadotrophins were studied in the same urine samples, and the mean excretion was 22 mouse units/24 hours (range 7–65 m. u.). The excretion mean for 17-ketosteroids, simultaneously studied, was 9.1 mg/24 hours (range 2.3–18.0 mg). Side-finding in the material were made: incipient cervical cancer in one patient, ovarial tumour in one, and trichomoniasis in seven.

scholarly journals Mild Joint Symptoms Are Associated with Lower Risk of Falls than Asymptomatic Individuals with Radiological Evidence of Osteoarthritis

PLoS ONE ◽  
2015 ◽  
Vol 10 (10) ◽  
pp. e0141368 ◽  
Author(s):  
Sumaiyah Mat ◽  
Pey June Tan ◽  
Chin Teck Ng ◽  
Farhana Fadzli ◽  
Faizatul I. Rozalli ◽  
...  
Keyword(s):  
Lower Risk ◽  
Radiological Evidence ◽  
Joint Symptoms ◽  
Risk Of Falls ◽  
Asymptomatic Individuals

Long-term results from a randomized blinded sham- and waitlist-controlled trial of acupuncture for joint symptoms related to aromatase inhibitors in early stage breast cancer (S1200).

2021 ◽  
Vol 39 (15_suppl) ◽  
pp. 12018-12018
Author(s):  
Dawn L. Hershman ◽  
Joseph M. Unger ◽  
Heather Greenlee ◽  
Jillian Capodice ◽  
Danika Lew ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Aromatase Inhibitors ◽  
Early Stage ◽  
Short Form ◽  
Controlled Trial ◽  
Musculoskeletal Symptoms ◽  
Long Term Results ◽  
Common Side Effect ◽  
Multicenter Randomized Controlled Trial ◽  
Joint Symptoms

12018 Background: Musculoskeletal symptoms are the most common side effect of aromatase inhibitors (AIs) among breast cancer (BC) survivors. We previously reported that true acupuncture (TA) resulted in better pain outcomes than either sham acupuncture (SA) or wait-list controls (WC) at 6 weeks with durable effects through 24 weeks, with minimal toxicity. We now report the 52-week outcomes. Methods: We conducted a SWOG multicenter randomized controlled trial among postmenopausal women with early-stage BC. Patients taking an AI for ≥30 days and reporting a worst pain score of ≥3 out of 10 using the Brief Pain Inventory-Worst Pain (BPI-WP) were eligible. Subjects were randomized 2:1:1 to TA vs. SA vs. WC. Both the TA and SA protocols consisted of a 12-week intervention, with 2 sessions per week for 6 weeks, followed by 1 session per week for 6 additional weeks. At 24 weeks, all subjects remained blinded to intervention arm but were offered 10 sessions of true acupuncture. Endpoints included BPI scores, the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) for hips and knees, the Modified Score for the Assessment of Chronic Rheumatoid Affections of the Hands (M-SACRAH), PROMIS Pain Inventory Short Form (PI-SF), and Functional Assessment of Cancer therapy Endocrine Symptoms (FACT-ES). Results: Among 226 patients registered, 110 were randomized to TA, 59 to SA and 57 to WC. Baseline characteristics were similar among the arms. At 52 weeks, follow-up assessments were available for 91 (82.7%) TA, 53 (89.8%) SA, and 47 (82.5%) WC patients. In a linear regression adjusting for the baseline score and stratification factors, 52-week mean BPI-WP scores were 1.08 points lower (correlating with less pain) in the TA compared to SA arm (95% CI: 0.24-1.91, p =.01), and were 0.99 points lower in the TA compared to WC arm (95% CI: 0.12-1.86, p =.03). The proportion of patients experiencing a clinically meaningful (>2) reduction (i.e. improvement) in BPI-WP was 64% for TA compared to 45% on SA and 53% on WC. Patients randomized to TA had reduced BPI pain interference at 52 weeks compared to SA (adjusted difference = 0.58, 95% CI: 0.00-1.16, p =.05) but not compared to WC (adjusted difference = 0.33, 95% CI: -0.28-0.93, p =.29). Also, at 52 weeks, patients randomized to TA had improved PROMIS PI-SF T-scores compared to SA (adjusted difference = 2.35, 95% CI: 0.07-4.63, p =.04) but not compared to WC (adjusted difference = 1.28, 95% CI: -1.09-3.66, p =.29). No statistically significant differences were observed in other measures. Conclusions: Women with breast cancer receiving AI therapy and treated with 12 weeks of TA for joint symptoms had reduced levels of worst pain compared to control patients, an effect that was durable through one year despite completion of protocol acupuncture at 12 weeks, and the offering of acupuncture to all participants at 24 weeks. Clinical trial information: NCT01535066.

Rheumatic Diseases of Childhood

1988 ◽  
Vol 10 (6) ◽  
pp. 183-190
Author(s):  
Robert M. Rennebohm
Keyword(s):  
Rheumatoid Arthritis ◽  
Adverse Effects ◽  
Juvenile Rheumatoid Arthritis ◽  
Chief Complaint ◽  
Musculoskeletal Complaints ◽  
Joint Symptoms ◽  
Rheumatic Conditions ◽  
Inflammatory Drugs ◽  
Systematic Collection ◽  
Age And Sex

The pediatrician frequently encounters children and adolescents with musculoskeletal complaints that raise the possibility of rheumatic disease. The purposes of this article are: to review an approach to the evaluation of "joint" symptoms and to review the pharmacology, use, and adverse effects of nonsteroidal anti-inflammatory drugs. RHEUMATOLOGIC HISTORY Systematic collection of the historical details is fundamental in the evaluation of "joint" complaints (Table 1). Age and Sex The child's age and sex provide initial clues. For example, suspicion that a young girl (less than 5 years of age) with knee swelling might have monoarticular juvenile rheumatoid arthritis is heightened simply because of her age and sex. (At onset of their disease, almost 20% of all patients with juvenile rheumatoid arthritis are young girls with pauciarthritis, most commonly involving the knee.) Suspicion that an older boy (10 years of age or older) with axioskeletal complaints might have an enthesopathy syndrome is increased, in part, because of his age and sex. of the age and sex predilections of various rheumatic conditions is, therefore, helpful. Chief Complaint The chief complaint is often directive. For example, the complaint "his knees hurt every night" or "his legs hurt at night" is not characteristic of children who have juvenile rheumatoid arthritis or other well-defined inflammatory arthritides.

scholarly journals Ethnicity, self-care, and use of medical care among the elderly with joint symptoms

1990 ◽  
Vol 3 (1) ◽  
pp. 19-28 ◽  
Author(s):  
Claudia J. Coulton ◽  
Sharon Milligan ◽  
Julian Chow ◽  
Marie Haug
Keyword(s):  
Medical Care ◽  
Self Care ◽  
The Elderly ◽  
Joint Symptoms

scholarly journals Prevalence and impact of joint symptoms in people with stroke aged 55 years and over

2011 ◽  
Vol 43 (3) ◽  
pp. 197-203 ◽  
Author(s):  
C Hettiarachchi ◽  
P Conaghan ◽  
A Tennant ◽  
B Bhakta
Keyword(s):  
Joint Symptoms
Sign in / Sign up

Export Citation Format

Share Document