Expression of retinoid receptors in hand eczema

2020 ◽  
Vol 59 (5) ◽  
pp. 576-581 ◽  
Author(s):  
Hanan Rabea Nada ◽  
Laila Ahmed Rashed ◽  
Dina Mahmoud Mustafa Elantably ◽  
Dina Ahmed El Sharkawy
Keyword(s):  
Hand Eczema ◽  
Retinoid Receptors

Hand eczema patients’ knowledge of skin protection following a guided talk—A retrospective study with a follow‐up questionnaire

2019 ◽  
Vol 81 (2) ◽  
pp. 117-123 ◽  
Author(s):  
Yasemin Topal ◽  
Tove Agner ◽  
Janique van der Heiden ◽  
Niels E. Ebbehøj ◽  
Kim K. B. Clemmensen
Keyword(s):  
Retrospective Study ◽  
Hand Eczema ◽  
Skin Protection

The association between atopic dermatitis and hand eczema: a systematic review and meta‐analysis

2018 ◽  
Vol 178 (4) ◽  
pp. 879-888 ◽  
Author(s):  
S.M.D. Ruff ◽  
K.A. Engebretsen ◽  
C. Zachariae ◽  
J.D. Johansen ◽  
J.I. Silverberg ◽  
...  
Keyword(s):  
Systematic Review ◽  
Atopic Dermatitis ◽  
Meta Analysis ◽  
Hand Eczema

scholarly journals Functional retinoid receptors in budding ascidians

2000 ◽  
Vol 42 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Mika Kamimura ◽  
Shigeki Fujiwara ◽  
Kazuo Kawamura ◽  
Toshitsugu Yubisui
Keyword(s):  
Retinoid Receptors

scholarly journals Targeted disruption of retinoic acid receptor alpha (RAR alpha) and RAR gamma results in receptor-specific alterations in retinoic acid-mediated differentiation and retinoic acid metabolism.

1995 ◽  
Vol 15 (2) ◽  
pp. 843-851 ◽  
Author(s):  
J F Boylan ◽  
T Lufkin ◽  
C C Achkar ◽  
R Taneja ◽  
P Chambon ◽  
...  
Keyword(s):  
Retinoic Acid ◽  
Retinoic Acid Receptor ◽  
Specific Gene ◽  
Cell Type ◽  
Targeted Disruption ◽  
F9 Cells ◽  
Retinoid Receptors ◽  
Alpha Gene ◽  
Polar Derivatives ◽  
Crabp Ii

F9 embryonic teratocarcinoma stem cells differentiate into an epithelial cell type called extraembryonic endoderm when treated with retinoic acid (RA), a derivative of retinol (vitamin A). This differentiation is presumably mediated through the actions of retinoid receptors, the RARs and RXRs. To delineate the functions of each of the different retinoid receptors in this model system, we have generated F9 cell lines in which both copies of either the RAR alpha gene or the RAR gamma gene are disrupted by homologous recombination. The absence of RAR alpha is associated with a reduction in the RA-induced expression of both the CRABP-II and Hoxb-1 (formerly 2.9) genes. The absence of RAR gamma is associated with a loss of the RA-inducible expression of the Hoxa-1 (formerly Hox-1.6), Hoxa-3 (formerly Hox-1.5), laminin B1, collagen IV (alpha 1), GATA-4, and BMP-2 genes. Furthermore, the loss of RAR gamma is associated with a reduction in the metabolism of all-trans-RA to more polar derivatives, while the loss of RAR alpha is associated with an increase in metabolism of RA relative to wild-type F9 cells. Thus, each of these RARs exhibits some specificity with respect to the regulation of differentiation-specific gene expression. These results provide an explanation for the expression of multiple RAR types within one cell type and suggest that each RAR has specific functions.

scholarly journals Effect of Retinoid Status on the Messenger Ribonucleic Acid Expression of Nuclear Retinoid Receptors α, β, and γ, and Retinoid X Receptors α, β, and γ in the Mouse Testis1

Endocrinology ◽  
1997 ◽  
Vol 138 (4) ◽  
pp. 1544-1551 ◽  
Author(s):  
Ingrid C. Gaemers ◽  
Ans M. M. van Pelt ◽  
Paul T. van der Saag ◽  
Jos W. Hoogerbrugge ◽  
Axel P. N. Themmen ◽  
...  
Keyword(s):  
Ribonucleic Acid ◽  
Retinoid X Receptors ◽  
Messenger Ribonucleic Acid ◽  
Retinoid Receptors ◽  
X Receptors
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