Human papillomavirus-associated cutaneous disease burden in human immunodeficiency virus (HIV)-positive patients: the role of human papillomavirus vaccination and a review of the literature

2017 ◽  
Vol 57 (6) ◽  
pp. 627-634 ◽  
Author(s):  
Lindsay C. Bacik ◽  
Catherine Chung
Keyword(s):  
Human Immunodeficiency Virus ◽  
Human Papillomavirus ◽  
Disease Burden ◽  
Hiv Positive ◽  
Review Of The Literature ◽  
Human Papillomavirus Vaccination ◽  
Cutaneous Disease ◽  
Immunodeficiency Virus

scholarly journals The Role of Human Papillomavirus in Human Immunodeficiency Virus Acquisition in Men who Have Sex with Men: A Review of the Literature

Viruses ◽  
2012 ◽  
Vol 4 (12) ◽  
pp. 3851-3858 ◽  
Author(s):  
Brandon Brown ◽  
Mariam Davtyan ◽  
Jerome Galea ◽  
Erica Chow ◽  
Segundo Leon ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Human Papillomavirus ◽  
Review Of The Literature ◽  
Virus Acquisition ◽  
Immunodeficiency Virus ◽  
Sex With Men

scholarly journals Human papillomavirus type-specific risk of cervical cancer in a population with high human immunodeficiency virus prevalence: case–control study

2011 ◽  
Vol 92 (12) ◽  
pp. 2784-2791 ◽  
Author(s):  
Pontus Naucler ◽  
Flora Mabota da Costa ◽  
Joao Leopoldo da Costa ◽  
Otto Ljungberg ◽  
Antonio Bugalho ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Human Immunodeficiency Virus ◽  
Human Papillomavirus ◽  
Effect Modification ◽  
Hiv Positive ◽  
Hpv 16 ◽  
Cervical Cancer Risk ◽  
Hiv Positive Women ◽  
Immunodeficiency Virus ◽  
Hiv Negative

There are limited data on human papillomavirus (HPV) type-specific cervical cancer risk among human immunodeficiency virus (HIV)-positive women. Previous studies have suggested that HPV 16 would be relatively less important as a causative agent among HIV-positive compared with HIV-negative women. This study investigates HPV type-specific cervical cancer risk in a population in which HIV is endemic. At the Central Hospital, Maputo, Mozambique, 221 cervical cancer cases and 203 hospital-based controls were consecutively enrolled. HPV typing from cervical samples, HIV testing and recording of socio-demographic factors were performed. Logistic regression modelling was used to assess HPV type-specific risk and effect modification between HIV and HPV infection. Infection with HPV 16, 18 and ‘high-risk non-HPV 16/18 types’ (HPV 31, 33, 35, 39, 45, 51, 52, 56, 58 and 59) was associated with cervical cancer in both crude and adjusted analyses. HPV 16 and 18 were the most common types detected in cancer biopsies among both HIV-negative and HIV-positive women. There was no significant evidence of effect modification between any HPV type and HIV infection, and there were no significant differences in the HPV type-specific prevalence when cervical cancers among HIV-positive and HIV-negative women were compared. Within the limitations of the study, the relative importance of different HPV types in cervical carcinogenesis appears not to be modified greatly by HIV infection, suggesting that HPV vaccines might not need to be type-specifically modified to be suitable for populations where HIV is endemic.

scholarly journals Human papillomavirus (HPV) genotypes and HPV16 variants in human immunodeficiency virus-positive Italian women

2008 ◽  
Vol 89 (6) ◽  
pp. 1380-1389 ◽  
Author(s):  
Maria Lina Tornesello ◽  
Maria Luisa Duraturo ◽  
Paolo Giorgi-Rossi ◽  
Matilde Sansone ◽  
Roberto Piccoli ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Human Papillomavirus ◽  
High Risk ◽  
Hiv Positive ◽  
Sequencing Analysis ◽  
Hiv Positive Women ◽  
Immunodeficiency Virus ◽  
Hpv Genotypes ◽  
Italian Women ◽  
Hiv Negative

Human immunodeficiency virus (HIV)-positive women have high rates of cervical squamous intraepithelial lesions (SIL) and concurrent human papillomavirus (HPV) infections with a variety of genotypes whose oncogenic risk is poorly documented. The prevalence and persistence of HPV genotypes and HPV16 variants were analysed in 112 HIV-positive and 115 HIV-negative Italian women. HIV-positive women were more likely than HIV-negative women to be infected by HPV at the initial examination (39.3 vs 13.9 %, P<0.001) and to have a higher period prevalence of HPV infection over a 3-year follow-up (43.8 % vs 17.4 %, P<0.001), regardless of CD4+ cell counts and anti-retroviral therapy. ‘High-risk’ and ‘probable high-risk’ HPVs (types 16, 18, 31, 33, 35, 45, 52, 58 and 66), among the 20 different viral genotypes identified, were predominant in HIV-positive (33.9 %) compared with HIV-negative (13.9 %) women. Among HIV-infected women, with normal cytology as well as with SIL of any grade, the most common genotypes were HPV16 followed by HPV81, -58, -72, -33 and -62. HPV16 isolates from 18 HIV-positive and eight HIV-negative women were classified into variant lineages based on sequencing analysis of E6 and E7 genes and the long control region. Whilst the HPV16 G350 European variant was prevalent in both HIV-positive (10.7 %) and -negative women (3.5 %), HPV16 African 2 variant was only detected in HIV-positive women (3.6 %), suggesting different sexual mixing behaviours. The increased prevalence of uncommon viral genotypes and HPV16 variants in HIV-positive Italian women underscores the need to target a wide range of HPV types in cervical screening of high-risk women.

scholarly journals The role of pain in quitting among human immunodeficiency virus (HIV)–positive smokers enrolled in a smoking cessation trial

2017 ◽  
Vol 38 (3) ◽  
pp. 249-252 ◽  
Author(s):  
Carrie J. Aigner ◽  
Ellen R. Gritz ◽  
Irene Tamí-Maury ◽  
George P. Baum ◽  
Roberto C. Arduino ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Smoking Cessation ◽  
Hiv Positive ◽  
Immunodeficiency Virus
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